1.

Record Nr.

UNINA9910678587003321

Titolo

New advances in neglected tropical diseases / / Marcia Aparecida Speranca, editor

Pubbl/distr/stampa

[London] : , : IntechOpen, , 2023

ISBN

1-80355-346-4

Descrizione fisica

1 online resource (132 pages)

Disciplina

616.9883

Soggetti

Neglected Diseases - prevention & control

Neglected Diseases - diagnosis

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

Advances in the understanding of neglected tropical diseases (NTDs) are inspiring the scientific community to investigate their eco-epidemiology and physiopathology, and to employ new biotechnological tools to fight against these devasting and complex infectious diseases which are associated with poverty. The topics covered include the employment of digital PCR and next-generation sequencing strategies to diagnose NTDs in hosts and reservoirs in urban and rural areas, and new findings on insects' reproductive biology that are enabling different vector control strategies. Eco-epidemiology of arboviruses in Latin America and physiopathology of Burili disease caused by Mycobacterium ulcerans are discussed, as is molecular characterization of Plasmodium vivax circumsporozoite protein (CSP) and its use in the epidemiology of malaria and vaccine development. Finally, the origin and pathogenic role of a serine protease inhibitor of Trypanosoma cruzi (TcISP2), the causative agent of Chagas disease, are explored.