1.

Record Nr.

UNINA9910463162303321

Autore

Garofalo Denise A

Titolo

Building communities : social networking for academic libraries / / Denise A. Garofalo

Pubbl/distr/stampa

Philadelphia, PA : , : Chandos Pub. an imprint of Woodhead Pub., , 2013

ISBN

1-78063-401-3

Edizione

[1st edition]

Descrizione fisica

1 online resource (243 p.)

Collana

Chandos Publishing social media series, , 2050-6813

Disciplina

302.3

Soggetti

Online social networks

Academic libraries - Information technology

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Cover; Building Communities : Social networking for academic libraries; Copyright; Dedication; Contents; List of figures; Acknowledgements; About the author; 1. The whats and whys of social networking for academic libraries; Background; Role on campus; Why social media for academic libraries?; Rewards of social media participation; 2. How to approach the implementation of social media technologies; Planning; Community-building; Survey of academic librarians using social media; 3. Case studies of academic libraries and social media networking; Libraries

Analysis of the experiences shared in case studies4. First steps; Strategy for implementing social media; Skill set defined; Sample social media policies; 5. Make the connection: posting on social media; Just DO it; Basic Facebook how-to section; Basic Twitter How-to Section; 6. Evaluating the impact of social media in academic libraries; How to evaluate; What to evaluate and what tools to use; Mid-course adjustments; 7. Closing thoughts; Appendix 1: Survey questions; Appendix 2: Case study questions; Appendix 3: Tools and resources; Glossary; References; Bibliography; Index

Sommario/riassunto

Social media is here to stay. A robust social media campaign can provide academic libraries with a means to showcase library resources, highlight content and events, and attract students to sample what the



library has to offer. Building Communities is a handbook to implement social media technologies for academic libraries. It is a guide to planning and implementing a successful social media campaign and evaluating its impact. This title covers: the beginning of social networking in the academic context; how to implement use of social media technologies; and evaluating their use. The final sec

2.

Record Nr.

UNINA9910677693003321

Titolo

Bacterial toxins : tools in cell biology and pharmacology / / Klaus Aktories (Ed.)

Pubbl/distr/stampa

London, [England] : , : Chapman & Hall, , 1997

©1997

ISBN

1-281-84256-7

9786611842567

3-527-61461-3

3-527-61460-5

Descrizione fisica

1 online resource (336 p.)

Collana

Laboratory Companion

Disciplina

579.3165

615.95293

Soggetti

Bacterial toxins

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"With 42 Figures"--Title page.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Nota di contenuto

Bacterial Toxins; Contents; CHAPTER 1 . Cholera Toxin: Mechanism of Action and Potential Use in Vaccine Development; 1.1 Introduction; 1.2 Molecular Aspects of Cholera Toxin Action; 1.2.1 Structure and Relationship to Other Toxins; 1.2.2 Toxin Entry into Cells and Events Leading to Pathogenesis; 1.2.3 Enzymology of Cholera Toxin; 1.2.4 In Vitro Stimulation of Cholera Toxin Activity by ARF; 1.3 Practical Aspects of Cholera Toxin Use; 1.3.1 Vaccine and Vaccine Development; 1.3.2 Cholera Toxin as a Molecular Tool; 1.4 Summary

CHAPTER 2 . Cholera Toxin and Escherichia coli Heat-labile Enterotoxin: Biochemical Methods for Assessing Enzymatic Activities2.1



Introduction; 2.2 General Information on CT. LT. ARF and Reagents; 2.2.1 Sources, Purification, and Activation of CTA and LTA; 2.2.2 Sources and Purification of ARF; 2.2.3 Reagents and Materials; 2.2.4 Stock Solutions; 2.3 Assay 1 : The Gsa Assay; 2.3.1 Additional Reagents and Materials Required; 2.3.2 Protocol; 2.4 Assay 2: The Agmatine Assay; 2.4.1 Additional Reagents and Materials Required; 2.4.2 Protocol; 2.5 Assay 3: Auto-ADP-ribosylation Assay

2.5.1 Additional Reagents and Materials Required2.5.2 Protocol; 2.6 Assay 4: NAD Glycohydrolase Assay; 2.6.1 Additional Reagents and Materials Required; 2.6.2 Protocol; 2.7 Comments and Considerations; 2.7.1 Appropriate Controls and Analysis of Data; 2.7.1.1 Controls; 2.7.1.2 Data analysis; 2.7.2 Optimization Interfering Substances, Troubleshooting, and Assay; 2.7.2.1 Interfering substances; 2.7.2.2 Troubleshooting; 2.7.2.3 Assay optimization; 2.7.3 Consideration for the Use of ARF; 2.7.3.1 Lipid/Detergent and Nucleotide Requirements; 2.7.3.2 Development of other Assay Conditions

CHAPTER 3 . Pertussis Toxin3.1 Introduction; 3.2 Genetic Regulation of Pertussis Toxin Production; 3.3 Biogenesis of Pertussis Toxin; 3.4 Receptor-binding and Translocation; 3.5 ADP-ribosyltransferase Activity and Enzyme Mechanism; 3.6 Biological Activities and Role of Pertussis Toxin in Pathogenesis; CHAPTER 4 . Pertussis Toxin as a Cell Biology Tool; 4.1 Introduction; 4.2 Pertussis Toxin as a Tool to Modify Cellular Functions; 4.2.1 Cell Culture of Bordetella pertussis; 4.2.2 Source of Pertussis Toxin and Preparation of Solution

4.2.3 Treatment of Mammalian Cell Cultures with Pertussis Toxin4.3 Pertussis Toxin as a Tool to Study Cellular Components; 4.3.1 Activation of Pertussis Toxin for in in vitro ADP- ribosylation; 4.3.2 Preparation of Cell Homogenates and Fractions; 4.3.3 ADP-ribosylation of Membrane Proteins by Pertussis Toxin; 4.3.4 ADP-ribosylation of Proteins by Pertussis Toxin; 4.3.5 Preparation of Samples for SDS-PAGE; 4.3.6 Cleavage of ADP-ribose from Ga Subunits; 4.4 SDS-Gel Electrophoresis; 4.5 Reagents and Chemicals; CHAPTER 5 . Clostridium botulinum ADP-ribosyltransferase C3; 5.1 Introduction

5.2 The Family of C3-like Transferases

Sommario/riassunto

This is a survey of well characterized and recently discovered bacterial protein toxins. Leading investigators of the respective toxins review the various molecular mechanisms of action, ranging from toxin-induced ADP-ribosylation up to membrane perforation by pore-forming toxins. Thy also describe the consequences on host physiology before focusing on potential applications as cell biological and pharmacological tools for research and medical applications. Detailed descriptions of the methodology include the engineering and use of modified and chimeric toxins for better performance.A soli