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1. |
Record Nr. |
UNINA9910674051303321 |
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Autore |
Jang Gilsoo |
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Titolo |
Power Electronics Applications in Renewable Energy Systems |
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Pubbl/distr/stampa |
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Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
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Descrizione fisica |
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1 electronic resource (258 p.) |
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Soggetti |
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Technology: general issues |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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The renewable generation system is currently experiencing rapid growth in various power grids. The stability and dynamic response issues of power grids are receiving attention due to the increase in power electronics-based renewable energy. The main focus of this Special Issue is to provide solutions for power system planning and operation. Power electronics-based devices can offer new ancillary services to several industrial sectors. In order to fully include the capability of power conversion systems in the network integration of renewable generators, several studies should be carried out, including detailed studies of switching circuits, and comprehensive operating strategies for numerous devices, consisting of large-scale renewable generation clusters. |
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2. |
Record Nr. |
UNINA9910357822903321 |
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Titolo |
HCV: The Journey from Discovery to a Cure : Volume I / / edited by Michael J. Sofia |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2019 |
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ISBN |
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Edizione |
[1st ed. 2019.] |
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Descrizione fisica |
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1 online resource (viii, 463 pages) |
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Collana |
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Topics in Medicinal Chemistry, , 1862-2461 ; ; 31 |
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Disciplina |
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Soggetti |
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Medicinal chemistry |
Virology |
Medical biochemistry |
Bioorganic chemistry |
Pharmaceutical technology |
Medicinal Chemistry |
Medical Biochemistry |
Bioorganic Chemistry |
Pharmaceutical Sciences/Technology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Identification of the virus, the medical need and clearing the blood supply -- Mapping the HCV genome -- The molecular virology of HCV -- The development of the HCV replicon system -- The Evolution of IFN therapy for HCV -- Evolution of HCV NS5B Non-Nucleoside Inhibitors -- Evolution of HCV NS5B Nucleoside & Nucleotide Inhibitors -- Discovery and Development of Sofosbuvir -- Discovery of Beclabuvir -- Discovery of Dasabuvir -- Evolution of HCV NS3/4 protease inhibitors -- Discovery and Development of Telaprevir -- Discovery and Development of Boceprevir -- Discovery and Development of Asunaprevir.-Discovery and Development of Grazoprevir -- Discovery and Development of Simeprevir -- Discovery and Development of Paritaprevir & Glecaprevir. |
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Sommario/riassunto |
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Hepatitis C is a liver disease caused by the hepatitis C virus (HCV) and infects approximately 75 million individuals worldwide. It is also one of |
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the major causes of liver cancer and liver transplants. The elucidation of the HCV genome, and the development of a whole cell system to study the virus spurred the search for novel direct acting antiviral drugs to cure this disease. This global effort culminated in the development of direct acting antiviral drugs that led to cure rates approaching 100% in all patient populations after only 8-12 weeks of therapy. These efforts resulted in one of the greatest achievements in public health and provides the potential for eliminating HCV as a major disease worldwide. This volume is aimed at a broad audience of academic and industrial scientists interested in the discovery and development of drugs to treat viral diseases and those interested in reading about one of the most unique accomplishments in biomedical research. The volume will provide a one of a kind reference work that highlights the many efforts, from the discovery of the HCV virus, to the invention of breakthrough medicines and their use in the real world to cure patients. It is the companion book to the volume "HCV: The Journey from Discovery to a Cure - Volume II". |
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