1.

Record Nr.

UNINA9910647773103321

Autore

Straub Rainer H.

Titolo

Early trauma as the origin of chronic inflammation : a psychoneuroimmunological perspective / / Rainer H. Straub

Pubbl/distr/stampa

Berlin, Germany : , : Springer, , [2023]

©2023

ISBN

9783662667514

9783662667507

Edizione

[1st ed. 2023.]

Descrizione fisica

1 online resource (267 pages)

Disciplina

616.0473

Soggetti

Inflammation

Psychic trauma in children

Psychoneuroimmunology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

Long shadows of early trauma - take a close look! -- What is childhood psychological trauma? -- Follow-up problems after early traumatic experiences -- Chronic immune activation -- Energy, early traumatic experiences and chronic immune activation.

Sommario/riassunto

The aim of the book is to sensitize physicians and researchers to the important long-term health effects of early, persistent, and severe trauma. The author, an internist, rheumatologist, and basic researcher in psychoneuroimmunology, shows connections between adverse childhood experiences and typical adult sequelae. After early traumatic experiences and childhood stress, there is a higher incidence of mental illness, chronic pain, sleep disorders, dental problems, obesity, cardiovascular disease, asthma, diabetes mellitus and chronic inflammation. A selection of diseases unmistakably demonstrate the long-term consequences of early childhood trauma. These childhood experiences create a kind of long-term programming that has a negative effect in adulthood. From his psychoneuroimmunological perspective, Rainer Straub identifies four factors that link the brain to the immune system and are involved in chronic immune activation: direct connectors originating in the brain, indirect connectors



functioning through hormonal and neuronal pathways, extracorporeal (the environmental factors) and pleiotropic (genetic factors) connectors. The author Prof. Rainer H. Straub, MD, is Professor of Experimental Medicine and is rheumatologist. He heads the Laboratory of Experimental Rheumatology and Neuroendocrine Immunology, Department of Internal Medicine at the University Hospital Regensburg. His nonfiction books "Understanding Aging, Fatigue, and Inflammation" (2018) and "Three Memories for the Body" (2020) have been published by Springer. The translation was done with the help of artificial intelligence. A subsequent human revision was done primarily in terms of content.