1.

Record Nr.

UNISA996466173503316

Titolo

Communicability, Computer Graphics, and Innovative Design for Interactive Systems [[electronic resource] ] : First International Symposium, CCGIDIS 2011, Córdoba, Spain, June 28-29, 2011, Revised Selected Papers / / edited by Francisco Cipolla Ficarra, Kim Veltman, Miguel Cipolla-Ficarra, Andreas Kratky

Pubbl/distr/stampa

Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2012

ISBN

3-642-33760-0

Edizione

[1st ed. 2012.]

Descrizione fisica

1 online resource (X, 145 p. 76 illus.)

Collana

Information Systems and Applications, incl. Internet/Web, and HCI ; ; 7545

Disciplina

006.6

Soggetti

User interfaces (Computer systems)

Multimedia systems 

Application software

Computer graphics

Architecture, Computer

User Interfaces and Human Computer Interaction

Media Design

Information Systems Applications (incl. Internet)

Computer Graphics

Computer System Implementation

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Bibliographic Level Mode of Issuance: Monograph

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

 communicability -- computer graphics -- innovative design of interactive systems.

Sommario/riassunto

This book constitutes the refereed proceedings of the First International Symposium on Communicability, Computer Graphics and Innovative Design for Interactive Systems, held in Córdoba, Spain, in June 2011. The 13 revised full papers presented were carefully reviewed and selected from various submissions. They examine latest breakthroughs and future trends within the communicability, computer graphics, and innovative design of interactive systems.



2.

Record Nr.

UNINA9910647231703321

Titolo

Frontiers of Targeted Therapy and Predictors of Treatment Response in Systemic Sclerosis / / by Michal Tomcik editor

Pubbl/distr/stampa

[Place of publication not identified] : , : MDPI - Multidisciplinary Digital Publishing Institute, , 2023

ISBN

3-0365-6122-6

Descrizione fisica

1 online resource (218 pages)

Disciplina

616.544

Soggetti

Systemic scleroderma

Scleroderma, Systemic - diagnosis

Scleroderma, Systemic - therapy

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

About the Editor vii -- Preface to "Frontiers of Targeted Therapy and Predictors of Treatment Response in Systemic Sclerosis " ix -- Frontiers of Targeted Therapy and Predictors of Treatment Response in Systemic Sclerosis 1 -- Therapeutic Options for Systemic Sclerosis: Current and Future Perspectives in Tackling -- Immune-Mediated Fibrosis 5 -- Targeting Systemic Sclerosis from Pathogenic Mechanisms to Clinical Manifestations: Why -- IL-6-37 -- Novel Concepts in Systemic Sclerosis Pathogenesis: Role for miRNAs 55 -- MiRNAs in Systemic Sclerosis Patients with Pulmonary Arterial Hypertension: Markers and Effectors 73 Inhibition of Hsp90 Counteracts the Established Experimental Dermal Fibrosis Induced by Bleomycin 91 -- Plasma Metabolomic Profiling Reveals Four Possibly Disrupted Mechanisms in Systemic Sclerosis 109 -- Autoantibodies as Biomarker and Therapeutic Target in Systemic Sclerosis 125 Emerging Evidence and Treatment Perspectives from Randomized Clinical Trials in Systemic Sclerosis: Focus on Interstitial Lung Disease 155 -- Clinical Predictors of Lung-Function Decline in Systemic-Sclerosis-Associated Interstitial Lung -- Disease Patients with Normal Spirometry 173 -- Treatment and Systemic Sclerosis Interstitial Lung Disease Outcome: The Overweight Paradox 185 -- Bisphosphonates for the Treatment of Calcinosis Cutis-A Retrospective Single-Center Study 199.



Sommario/riassunto

Systemic sclerosis (scleroderma) is an incurable connective tissue disease with an unclear etiology characterized by vasculopathy, dysregulation of the immune response, and progressive tissue fibrosis affecting the skin, lungs, digestive tract, heart, and kidneys. The collection of six original research manuscripts and five review articles included in this book highlights the most recent advances in this field and provides further elucidation of the pathogenesis, natural disease course, and treatment of this challenging disease.