1.

Record Nr.

UNINA9910349465703321

Titolo

Advancement in the Pathophysiology of Cerebral Stroke / / edited by Ranjana Patnaik, Amit Kumar Tripathi, Ashish Dwivedi

Pubbl/distr/stampa

Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2019

ISBN

981-13-1453-5

981-13-1452-7

Edizione

[1st ed. 2019.]

Descrizione fisica

1 online resource (VIII, 189 p. 23 illus., 12 illus. in color.)

Disciplina

612

Soggetti

Human physiology

Neurosciences

Cytology

Stress (Physiology)

Radiology

Stem cells

Nanotechnology

Human Physiology

Neuroscience

Cellular Stress

Stem Cell Biology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Chapter 1. Cerebral stroke: An Introduction -- Chapter 2. Inflammation, oxidative stress, and neurodegeneration -- Chapter 3. Stroke induced blood brain barrier damage -- Chapter 4. Regulation of calcium ions in ischemic neuronal cell -- Chapter 5. Ischemic stroke induced endoplasmic reticulum stress -- Chapter 6. The role of autophagy in ischemic stroke: friend or foe?- Chapter 7. Critical role of mitochondrial autophagy in cerebral stroke -- Chapter 8. Application of neuroimaging in the identification of the pinpoint location of blockage -- Chapter 9. Emerging role of the electromagnetic field in stroke -- Chapter 10. Stem cell therapies for stroke -- Chapter 11. MicroRNA: Significance to stroke diagnosis, prognosis, and therapy -- Chapter



12. Therapeutic Aspects of Nanomedicines in Stroke Treatment -- Chapter 13. Neuroprotective potential of small molecule phytochemicals against stroke -- Chapter 14. Role of UV irradiation on neuroprotective potential of phytochemicals -- Chapter 15. Post-stroke treatment strategies, management, and rehabilitation.

Sommario/riassunto

This book provides detailed and comprehensive mechanistic insights of the various risk factors that lead to the ischemic stroke and the novel therapeutic interventions against it. The first section discusses the different ischemic cerebral stroke-induced inflammatory pathways and dysfunctionality of blood-brain barrier. The later sections of the book deals with the role of endoplasmic reticulum stress and mitophagy in cerebral stroke and introduces the different neuroimaging techniques such as Computed tomography (CT), Magnetic resonance imaging (MRI), Positron emission tomography (PET) and Single-Photon emission computed tomography (SPECT) that are used to identify the arterial blockages. The final section comprises of chapters that focus on various neuroprotective strategies and emerging therapeutic interventions for combating stroke pathophysiology. The chapters cover the role of stem cell therapy, the therapeutic effect of low-frequency electromagnetic radiations (LF-EMR), and implications of non-coding RNAs such as micro-RNAs as the biomarkers for diagnosis, prognosis, and therapy in ischemic stroke.



2.

Record Nr.

UNINA9910645987603321

Autore

Cercas Javier <1962->

Titolo

The vision and the path / European Investment Bank, Javier Cercas . Volume 11

Pubbl/distr/stampa

[s.l.] : , : European Investment Bank, , 2019

ISBN

9789286143830

9286143834

Descrizione fisica

1 online resource (44 p.)

Soggetti

Business & Economics / Finance

Economics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

What is Europe? A continent fragmented through the centuries by wars, border conflicts and cultural diversity. As Europeans, we do not have a common language or a common history, but we do have common roots, needs and ambitions. These similarities led us to fulfil what at the end of the Second World War could have been called a "reasonable utopia" - the European Union. The Spanish writer Javier Cercas investigates Europe and Europeans, our past, the conflicts, the ideologies and the people who forged Europe as we know it today. Though no final answer to all the questions can be found, the conclusion seems inevitable: Europe will be unified, naturally, sooner or later, despite all the hostility. This is the eleventh essay in the Big Ideas series created by the European Investment Bank. The EIB has invited international thought leaders to write about the most important issues of the day. These essays are a reminder that we need new thinking to protect the environment, promote equality and improve people's lives around the globe.