Ciba Foundation Symposium on Drug Resistance in Micro-Organisms [[electronic resource] ] : mechanisms of development. / / editors for the Ciba Foundation, G.E.W. Wolstenholme and Cecilia M. O'Connor

• Record Nr.: UNINA9910643378903321
• Pubbl/distr/stampa: Boston, : Little, Brown, [1957]
• ISBN: 1-280-76861-4; 9786613679383; 0-470-71905-2; 0-470-71652-5
• Descrizione fisica: 1 online resource (384 p.)
• Collana: Ciba Foundation symposium
• Altri autori (Persone): WolstenholmeG. E. W (Gordon Ethelbert Ward); O'ConnorCecilia M <1927-> (Cecilia Mary)
• Disciplina: 600
• Soggetti: Drug resistance in microorganisms
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and indexes.
• Nota di contenuto: DRUG RESISTANCE IN MICRO-ORGANISMS; CONTENTS; Chairman's opening remarks; Aspects of the problem of drug resistance in bacteria; Discussion; Indirect selection and origin of resistance; Discussion; Genetic aspects of drug resistance; Discussion; Inheritance in single bacterial cells; Discussion; Penicillin-induced resistance to penicillin in cultures of Bacillus cereus; Discussion; Directed hereditary changes of fermentative properties of yeast by a specific substrate; Discussion; Multiple mechanisms of acquired drug resistance; Discussion; Physiological (phenotypic) mechanisms responsible for drug resistanceDiscussion; Genetic and metabolic mechanisms underlying multiple levels of sulphonamide resistance in pneumococci; Discussion; The phenotypic expression of genes determining various types of drug resistance following their inheritance by sensitive bacteria; Discussion; Specific polyhydroxy compounds as cofactors of enzymic adaptation and its inheritance; Discussion; Development of resistance to streptomycin in Serratia marcescens; Discussion; Distribution of drug-resistant individuals in cultures of Mycobacterium ; tuberculosisDiscussion; Physiological adaptation of bacteria to antibiotics; Discussion; Drug resistance of staphylococci with special reference to penicillinase production; Discussion; On the identification of genetic and non-genetic variation in bacteria; Discussion; The reactions of the mutagenic alkylating agents with proteins and nucleic acids; Discussion; Genetics of two different mechanisms of resistance to colicins: resistance by loss of specific receptors and im- munity by transfer of colicinogenic factors; DiscussionGeneral Discussion; Chairman's closing remarks