Ontogeny of acquired immunity / / Ciba Foundation

• Record Nr.: UNINA9910643263703321
• Pubbl/distr/stampa: Amsterdam, [Netherlands] ; ; London, [England] ; ; New York, New York : , : Associated Scientific Publishers, , 1972; ©1972
• ISBN: 1-283-57215-X; 9786613884602; 0-470-71988-5; 0-470-71754-8
• Descrizione fisica: 1 online resource (284 p.)
• Collana: Ciba Foundation Symposium
• Disciplina: 616.07/9; 616.079
• Soggetti: Immunity
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references at the end of each chapters and index.
• Nota di contenuto: Ontogeny of Acquired Immunity; Contents; Contributors; Introduction; 1 What Precedes Clonal Selection?; THE CLONAL SELECTION THEORY; THE ANTIBODY REPERTOIRE; THE AVAILABLE REPERTOIRE; REPERTOIRE SUPPRESSION; SOURCE OF THE REPERTOIRE; BOUNDARY CONDITIONS; References; Discussion; References; 2 Immunological maturation in the foetus: modulation of the pathogenesis of congenital infectious diseases; ONTOGENESIS OF THE IMMUNE RESPONSE; IMMUNOLOGICAL SUPPRESSION OF PATHOGENICITY; THE IMMUNOLOGICAL ACTIVATION OF PATHOGENlClTY; THE IMMUNOLOGICAL MODULATION OF PATHOGENESIS; IMMUNOLOGICAL TOLERANCE IN CONGENITAL INFECTIONSUMMARY; ACKNOWLEDGEMENTS; References; Discussion; References; 3 The origins and development of lymphocyte populations; EMBRYONIC HAEMOPOIESIS: DEFINITION, DERIVATION, POTENTIALITIES AND NATUREOF STEM CELLS; LYMPHOPOIESlS IN THE CHICK EMBRYO; SUMMARY; References; Discussion; THETA SPECIFICITY; FUNCTIONAL DIFFERENCES AMONG T CELLS; ANTI-RECEPTOR ANTIBODIES; ; References; 4 Ontogeny of components of complement and lysozyme; COMPLEMENT; LYSOZYME; SUMMARY; ACKNOWLEDGEMENTS; References; Discussion; References; 5 Allotype suppression; ALLOTYPE SUPPRESSION IN HETEROZYGOTESALLOTYPE SUPPRESSION IN HOMOZYGOTES; CHARACTERISTICS OF ALLOTYPE SUPPRESSION; SUMMARY; References; Discussion; References; 6 Development of cellular immunocompetence in man; BLASTOGENIC RESPONSE OF FOETAL LYMPHOCYTES TO PHA; PHA-MEDIATED LYMPHOCYTOTOXICITY BY HUMAN FOETAL LYMPHOCYTES; DEVELOPMENT OF THE ROSETTE-FORMING CELL IN THE HUMAN FOETUS; SUMMARY; ACKNOWLEDGEMENTS; References; Discussion; References; 7 The role of serum factors ('blocking antibodies') as mediators of immunological non-reactivity to cellular antigens; 'BLOCKING ANTIBODIES' TO TUMOUR-ASSOCIATED (SPECIFIC) ANTIGENSEVIDENCE FOR 'BLOCKING ANTIBODIES' IN PREGNANT MICE; BLOCKING SERUM ACTIVITY IN MICE 'TOLERANT' OF ALLOGRAFTS; WHAT IS THE NATURE OF THE BLOCKING FACTORS AND HOW DO THEY ACT?; SUMMARY; ACKNOWLEDGEMENTS; References; Discussion; References; 8 Concerning the uterus as a graft site and the foetus as a natural parabiotic organismic homograft; ANALYSIS OF THE UTERUS AS A GRAFT SITE; STUDIES ON THE IMMUNOLOGICAL CONSEQUENCES OF A PUTATIVE NATURAL MATERNAL-FOETAL TRANSMISSION OF CELLS IN RATS; DISCUSSION; SUMMARY; ACKNOWLEDGEMENT; ReferencesDiscussion; References; 9 Bone marrow transplantation in a genetically determined anaemia in the mouse; EXPERIMENTS IN NEONATAL MICE; EXPERIMENTS IN ADULT MICE; DISCUSSION; SUMMARY; ACKNOWLEDGEMENTS; References; Discussion; References; 10 Genetic deficiencies of the complement system; GENETIC DEFICIENCIES OF COMPLEMENT COMPONENTS; DEFICIENCY OF COMPLEMENT INHIBITORS; ACKNOWLEDGEMENTS; References; Discussion; References; 11 Defects in immunological development in man; AETIOLOGICAL CONSIDERATIONS; SUMMARY; References; Discussion; References; 12 Treatment of immune deficiency disease with bone marrow stem cell concentrates