1.

Record Nr.

UNINA9910639995703321

Autore

Shoyama Kikuko

Titolo

Ecosystem Service and Land-Use Changes in Asia : Implications for Regional Sustainability

Pubbl/distr/stampa

Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022

ISBN

3-0365-5855-1

Descrizione fisica

1 electronic resource (328 p.)

Soggetti

Research & information: general

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

This book highlights the role of research in Ecosystem Services and Land Use Changes in Asia. The contributions include case studies that explore the impacts of direct and indirect drivers affecting provision of ecosystem services in Asian countries, including China, India, Mongolia, Sri Lanka, and Vietnam. Findings from these empirical studies contribute to developing sustainability in Asia at both local and regional scales.



2.

Record Nr.

UNINA9910557304003321

Autore

Denora Nunzio

Titolo

Paediatric Formulation: Design and Development

Pubbl/distr/stampa

Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021

Descrizione fisica

1 online resource (205 p.)

Soggetti

Medicine

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

The development of paediatric medicines can be challenging since this is a different patient population with specific needs. A medicine designed for use in paediatric patients must consider the following aspects: patient population variability; the need for dose flexibility; route of administration; patient compliance; excipient tolerability. For example, the toxicity of excipients may differ in children compared to adults and children have different taste preferences. Globally, about 75% of drugs do not carry regulatory approval for use in children; worldwide, many medications prescribed for the treatment of paediatric diseases are used off-label, and less than 20% of package inserts have sufficient information for treating children. This book provides an update on both state-of-the-art methodology and operational challenges in paediatric formulation design and development. It aims at re-evaluating what is needed for more progress in the design and development of age-appropriate treatments for paediatric diseases, focusing on: formulation development; drug delivery design; efficacy, safety, and tolerability of drugs and excipients.