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1. |
Record Nr. |
UNINA9910455498103321 |
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Autore |
Chatterjee D |
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Titolo |
Topology [[electronic resource] ] : general and algebraic / / D. Chatterjee |
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Pubbl/distr/stampa |
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New Delhi, : New Age International (P) Ltd., Publishers, c2007 |
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ISBN |
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1-282-12890-6 |
9786612128905 |
81-224-2704-9 |
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Descrizione fisica |
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1 online resource (176 p.) |
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Disciplina |
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Soggetti |
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Topology |
Algebraic topology |
Topological spaces |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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Cover; Preface; Contents; Part I; Chapter 1 Sets, Relations and Functions; Chapter 2 Topologies of R and R2; Chapter 3 Metric Space; Chapter 4 Topological Spaces; Chapter 5 Separation Axioms; Chapter 6 Compactness; Chapter 7 Connectedness; Part II; Chapter 1 Algebraic Preliminaries; Chapter 2 Homotopy Theory; Chapter 3 Compact Open Topology; Chapter 4 Higher Homotopy Groups; Chapter 5 Surfaces, Manifolds and CW Complexes; Chapter 6 Simplicial Homology Theory; Chapter 7 Singular Homology Theory; Chapter 8 Manifold Analysis; Chapter 9 Fibre Bundles; Bibliography |
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Sommario/riassunto |
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About the Book: This book provides exposition of the subject both in its general and algebraic aspects. It deals with the notions of topological spaces, compactness, connectedness, completeness including metrizability and compactification, algebraic aspects of topological spaces through homotopy groups and homology groups. It begins with the basic notions of topological spaces but soon going beyond them reaches the domain of algebra through the notions of homotopy, homology and cohomology. How these approaches work in |
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harmony is the subject matter of this book. The book finally arrives at the |
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2. |
Record Nr. |
UNINA9910639877503321 |
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Autore |
Macheras P (Panos) |
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Titolo |
Revising Oral Pharmacokinetics, Bioavailability and Bioequivalence Based on the Finite Absorption Time Concept / / by Panos Macheras, Athanasios A. Tsekouras |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
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ISBN |
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Edizione |
[1st ed. 2023.] |
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Descrizione fisica |
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1 online resource (137 pages) |
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Collana |
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Biomedical and Life Sciences Series |
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Disciplina |
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Soggetti |
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Pharmaceutical chemistry |
Pharmacology |
Pharmacy |
Biomedical engineering |
Pharmaceutics |
Biomedical Engineering and Bioengineering |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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Part I: Oral Pharmacokinetics -- Chapter 1. From Bateman (1908) To Dost (1953) -- Chapter 2. The Unphysical Hypothesis Of Infinite Absorption Time -- Chapter 3. The Finite Absorption Time (Fat) Concept -- Chapter 4. The Rise Of Physiologically Based Finite Time Pharmacokinetic (Pbftpk) Models -- Part II: Bioavailability-Bioequivalence -- Chapter 5. History Of The Bioavailability-Bioequivalence Concepts -- Chapter 6. Therapeutic Equivalence Based On Bioequivalence Studies -- Chapter 7. Bioavailability Under The Prism Of Finite Absorption Time -- Chapter 8. Bioequivalence Under The Prism Of Finite Absorption Time. |
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Sommario/riassunto |
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This book casts new light on the field of oral drug absorption. It outlines both the concept of the past and the novel concept of Finite |
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Absorption Time (FAT). In addition, the authors explore the correlated need for re-definition of bioavailability, bioequivalence providing a plethora of experimental data. Accordingly, this book is intended for academics/students or scientists working in pharmaceutical industries, regulatory agencies, and contract research organizations. It can be used for teaching purposes in under- and post-graduate courses dealing with biopharmaceutics, pharmacokinetics and biomedical engineering. This excellent text serves as a historical review of drug absorption kinetics and its application to bioavailability and bioequivalence. However, its main thrust is the application of the authors' innovative new approaches to modifying these processes utilizing concepts of finite absorption time (FAT) and physiologically based finite time pharmacokinetic (PBFTPK) models. The work described in detail is based on the innovative experimental studies, many in depth examples and simulations, and the authors' outstanding theoretical contributions to our understanding of drug gastrointestinal absorption, and drug pharmacokinetics. I found the book to be an enjoyable and enlightening read. Professor Leslie Benet, Department of Bioengineering & Therapeutic Sciences, Schools of Pharmacy & Medicine, University of California, San Francisco, USA. |
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