| |
|
|
|
|
|
|
|
|
1. |
Record Nr. |
UNINA9910454158603321 |
|
|
Autore |
Reed Lynn Raphael |
|
|
Titolo |
Creating gender-fair schools and classrooms [[electronic resource] ] : engendering social justice, 14-19 / / Lynn Raphael Reed and Tina Rae |
|
|
|
|
|
|
|
Pubbl/distr/stampa |
|
|
London, : Paul Chapman, 2007 |
|
|
|
|
|
|
|
ISBN |
|
1-282-56022-0 |
9786612560224 |
1-84860-563-3 |
|
|
|
|
|
|
|
|
Descrizione fisica |
|
1 online resource (311 p.) |
|
|
|
|
|
|
Collana |
|
|
|
|
|
|
Altri autori (Persone) |
|
|
|
|
|
|
Disciplina |
|
|
|
|
|
|
Soggetti |
|
Sex differences in education - Great Britain |
Discrimination in education - Great Britain - Prevention |
Multicultural education - Great Britain |
Sex differences (Psychology) in children - Great Britain |
Sex role in children - Great Britain |
Education, Secondary - Great Britain |
Electronic books. |
|
|
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Note generali |
|
Description based upon print version of record. |
|
|
|
|
|
|
Nota di bibliografia |
|
Includes bibliographical references. |
|
|
|
|
|
|
Nota di contenuto |
|
Cover; Contents; Introduction; Chapter 1; Chapter 2; Chapter 3; Chapter 4; Chapter 5; CD-Rom Worksheets |
|
|
|
|
|
|
|
|
Sommario/riassunto |
|
Gender issues related to role models, image & expectations have an effect upon the behaviour & achievement of both boys & girls. For teachers of students aged 14-19, this text provides a programme to promote gender equality & inclusivity in schools & colleges, a rationale for the programme based on social justice & a practical set of classroom activities to implement the programme. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
2. |
Record Nr. |
UNINA9910635394703321 |
|
|
Autore |
Byun Wan Gi |
|
|
Titolo |
Discovery of Small-Molecule Modulators of Protein–RNA Interactions for Treating Cancer and COVID-19 / / by Wan Gi Byun |
|
|
|
|
|
|
|
Pubbl/distr/stampa |
|
|
Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2023 |
|
|
|
|
|
|
|
ISBN |
|
9789811978142 |
9789811978135 |
|
|
|
|
|
|
|
|
Edizione |
[1st ed. 2023.] |
|
|
|
|
|
Descrizione fisica |
|
1 online resource (156 pages) |
|
|
|
|
|
|
Collana |
|
Springer Theses, Recognizing Outstanding Ph.D. Research, , 2190-5061 |
|
|
|
|
|
|
|
|
Disciplina |
|
|
|
|
|
|
Soggetti |
|
Bioengineering |
Biotechnology |
Biophysics |
Protein folding |
RNA interference |
Biological and Physical Engineering |
Chemical Bioengineering |
Protein Folding |
RNA Interference |
|
|
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Note generali |
|
"Doctoral thesis accepted by Seoul National University, Seoul, Korea (Republic of)" |
|
|
|
|
|
|
|
|
Nota di contenuto |
|
1. Introduction -- 2. Identification of Small-Molecule Inhibitors of Oncogenic Lin28–Let-7 Interaction -- 3. Discovery of Small-Molecule Modulators of Protein–RNA Interactions by Fluorescence Intensity-Based Binding Assay -- 4. Harnessing Stress Granule Formation by Small Molecules to Inhibit the Cellular Replication of SARS-CoV-2 -- Appendix. |
|
|
|
|
|
|
|
|
Sommario/riassunto |
|
This book describes the development of novel protein–RNA-binding assays and their applications in a high-throughput manner for the identification of small-molecule modulators of protein–RNA interactions to treat cancer and COVID-19. Modulating protein–RNA interactions with small molecules is expected to provide novel biological insights of the interrelation of diseases with the protein–RNA |
|
|
|
|
|
|
|
|
|
|
interactome. The modulations may also be exploited therapeutically. For these reasons, the development of a simple, reliable, and sensitive protein–RNA-binding assay is necessary for high-throughput screening to discover new effective chemical entities capable of acting on diverse protein–RNA interactions. This book discusses the discovery of small-molecule modulators targeting protein–RNA interactions that are potentially valuable to treat cancer and COVID-19 by constructing novel high-throughput screening methods. The results of this dissertation provide valuable insights into the regulation of protein–RNA interactions in chemical biology and drug development. |
|
|
|
|
|
| |