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Record Nr. |
UNINA9910454078003321 |
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Titolo |
Metal ions and neurodegenerative disorders [[electronic resource] /] / editor, Paolo Zatta |
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Pubbl/distr/stampa |
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New Jersey, : World Scientific, c2003 |
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ISBN |
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1-281-95608-2 |
9786611956080 |
981-279-669-X |
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Descrizione fisica |
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1 online resource (538 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Metal ions - Physiological effect |
Molecular neurobiology |
Nervous system - Degeneration |
Neurotoxicology |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Contents ; Preface ; List of Contributors ; Chapter 1. Metal-Catalyzed Redox Activity in Neurodegenerative Disease ; 1. INTRODUCTION ; 1.1. Redox-Active Transition Metals in AD ; 1.2. Aggregation of Amyloid-B and Amyloid B Protein Precursor/Amyloid-p-Linked ROS Production |
1.3. Iron in Neurodegenerative Disease 1.4. Iron-Mediated Oxidative Stress in Parkinson's Disease ; 1.5. Manganese and Parkinson's Disease ; 1.6. Antioxidant and Transition Metal Homeostasis ; 1.7. CuZnSOD Mutations and Familial Amyotrophic Lateral Sclerosis ; 2. CONCLUSIONS |
Chapter 2. Metals Distribution and Regionalization in the Brain 1. TRACE ELEMENT DISTRIBUTION IN NORMAL HUMAN BRAIN ; 1.1. Aluminum Iron Copper and Zinc Distribution in Normal Human Brain Sites in Relation to Age ; 1.2. Aluminum ; 1.3. Iron ; 1.4. Copper |
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; 1.5. Zinc |
2. TRACE ELEMENT IMBALANCES IN NEURODEGENERATIVE DISEASES 2.1. Aluminum Iron Copper and Zinc in Alzheimer's Disease ; 2.2. Factors Affecting the Final Results ; 2.3. Aluminum Iron Copper and Zinc in Parkinson's Disease |
2.4. Aluminum Iron Copper and Zinc in Western Pacific Parkinsonism-Dementia 2.5. Aluminum Iron Copper and Zinc in Amyotrophic Lateral Sclerosis ; 3. FINAL REMARKS ; Chapter 3. The Olfactory Pathway as a Route of Entry of Metals into the Brain ; 1. INTRODUCTION |
2. ANATOMY OF THE OLFACTORY SYSTEM |
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Sommario/riassunto |
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Numerous studies have established a clear connection between neuronal oxidative stress and several neurodegenerative diseases, with consequential damages to lipids, proteins, nucleic acids, etc. In addition, several modifications indicative of oxidative stress have been described in association with neurons, neurofibrillary tangles and senile plaques in Alzheimer's disease, including advanced glycation end products and free carbonyl oxidation. Oxidative damage and antioxidant responses are now well characterized, but sources of damaging free radicals are yet to be fully understood. Evidences |
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2. |
Record Nr. |
UNINA9910633961503321 |
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Titolo |
Facial nerve palsy : a practitioner's guide / / edited by Pratap Sanchetee, Kirti Sachdev, R. Rajeswari |
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Pubbl/distr/stampa |
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London : , : IntechOpen, , 2022 |
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ISBN |
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Descrizione fisica |
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1 online resource (84 pages) |
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Disciplina |
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Soggetti |
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Facial paralysis - Treatment |
Facial paralysis - Diagnosis |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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1. Introductory Chapter: Bell's Palsy -- 2. Medical System to Evaluate the Seventh Cranial Nerve through the Main Facial Mimic Muscles -- 3. Comprehensive Rehabilitation of Patients with Facial Expression Asymmetry and Synkinesis with Botulinum Toxin Type A and Monofilament Mesothreads -- 4. Reanimation of Mouth Corner with Free Gracilis Muscle Flap -- 5. Management of Bell's Palsy with Phototherapy. |
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Sommario/riassunto |
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The 7th cranial nerve, commonly known as the facial nerve, is a compound nerve having motor, parasympathetic and sensory components. Its motor portion innervates muscles for facial movement and expression. Facial paralysis is a common clinical condition that significantly impacts a patient's quality of life. Clinical evaluation is the primary diagnostic tool, and advanced imaging techniques are usually not needed. While a majority of patients with Bell's palsy recover spontaneously, patients are generally treated with a combination of steroids, antiviral drugs, and physiotherapy. In this book, experts discuss recent advances in the diagnosis and management of 7th cranial nerve paralysis, along with surgical options. |
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