1.

Record Nr.

UNINA9910627285103321

Titolo

Bacterial pili : structure, synthesis and role in disease / / edited by Michèle A. Barocchi and John L. Telford ; contributors Edward N. Baker [and nine others] ; Rachel Cutts, commissioning editor ; Emma McCann, editorial assistant

Pubbl/distr/stampa

Wallingford, England ; ; Boston, Massachusetts : , : CABI, , 2014

©2014

ISBN

1-78639-528-2

1-78924-374-2

1-78064-256-3

Descrizione fisica

1 online resource (220 p.)

Collana

Advances in molecular and cellular microbiology ; ; 27

Disciplina

579.26

Soggetti

Pili (Microbiology)

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Includes index.

Nota di contenuto

Contents; Contributors; Foreword; 1 The Vibrio cholerae Toxin Coregulated Pilus: Structure, Assembly and Function with Implications for Vaccine Design; 2 Conjugative Pili; 3 Pilus Biogenesis by the Chaperone-Usher Pathway; 4 Type 1 and P Pili of Uropathogenic Escherichia coli; 5 Type IV Pili: Functions and Biogenesis; 6 The Pseudomonas aeruginosa Type IV Pilus Assembly System in Three Dimensions; 7 Corynebacterium diphtheriae Pili: Assembly, Structure and Function; 8 Three-dimensional Structures of Pilin Subunits and their Role in Gram-positive Pilus Assembly and Stability

9 Sortase Structure and Specificity in Streptococci10 Pili of Streptococcus pyogenes; 11 The Role of Pili in the Formation of Biofilm and Bacterial Communities; 12 Fimbriae/Pili from Oral Bacteria; 13 Pilus-based Vaccine Development in Streptococci: Variability, Diversity and Immunological Responses; Index; A; B; C; D; E; F; G; H; I; L; M; N; O; P; R; S; T; U; V; Y

Sommario/riassunto

Bacterial pili play important roles as environmental sensors, in host colonization and in biofilm formation, enabling bacteria to interact with the environment, with surfaces and with other bacteria and host cells.



Most bacteria, both Gram positive and Gram negative, and almost all bacterial pathogens, are piliated. This book discusses the synthesis, structure, evolution, function and role in pathogenesis of these complex structures, and their basis for vaccine development and therapeutics for Streptococcus pathogens. It is an invaluable resource for researchers and students of medical microbi