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1. |
Record Nr. |
UNINA990000862220403321 |
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Autore |
Capobussi, Paolo |
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Titolo |
Comunicare con il modem : uso e applicazi oni / P. Capobussi |
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Pubbl/distr/stampa |
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Milano : Gruppo Edit. Jackson S.P.A, 1990 |
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ISBN |
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Descrizione fisica |
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Disciplina |
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Locazione |
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Collocazione |
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Materiale a stampa |
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Livello bibliografico |
Monografia |
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2. |
Record Nr. |
UNISA990001593290203316 |
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Autore |
FREYRE, Gilberto |
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Titolo |
Padroni e schiavi / Gilberto Freyre ; introduzione di Braudel ; traduzione di A. Pascetto |
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Pubbl/distr/stampa |
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Descrizione fisica |
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XV, 548 p. ; in 8°, 22 cm |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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3. |
Record Nr. |
UNINA9910619465503321 |
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Autore |
Allison Simon J |
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Titolo |
Novel Anti-cancer Agents and Cellular Targets and Their Mechanism(s) of Action |
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Pubbl/distr/stampa |
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MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
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ISBN |
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Descrizione fisica |
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1 online resource (206 p.) |
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Soggetti |
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History of engineering & technology |
Technology: general issues |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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Patient outcomes remain poor for many cancers despite improvements in treatments and new molecular-targeted biomedicines for certain cancer types or subtypes. Dose-limiting toxicity, a narrow therapeutic index, and the development of resistance to traditional anti-cancer agents are well-established. It is apparent that inherent and acquired drug resistance are major challenges with molecular-targeted agents and that on- as well as off-target side effects can still occur. Other issues include drug metabolism by the body and safely supplying a sufficient amount of active drug to the tumor cells. There is a clear and urgent need for new molecular targets and drugs that specifically target cancer cells in different ways to existing approved drugs. This book, through a collection of eight research articles and two review articles from the Biomedicines themed Special Issue 'Novel Anti-Cancer Agents and Cellular Targets and Their Mechanism(s) of Action', provides a snapshot of some of the diverse and exciting research approaches being taken by the cancer research community in trying to address some of these therapeutic challenges. |
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