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Record Nr. |
UNISA996386930503316 |
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Autore |
Wild Robert <1609-1679.> |
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Titolo |
The grateful non-conformist; or A return of thanks to Sir John Baber Knight, and Doctor of Physick who sent the author ten crowns [[electronic resource]] |
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Pubbl/distr/stampa |
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London, : [s.n.], printed in the year 1665 |
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Descrizione fisica |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Attributed to Robert Wild by Wing. |
Verse - "Ten crowns at once! and to one man! and he". |
A satirical attack on Sir John Baber, M.D., who was often employed by Charles II to negotiate with puritans and other non-conformists. |
Reproductions of the originals in the British Library and Bodleian Library. |
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Sommario/riassunto |
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2. |
Record Nr. |
UNINA9910596998503321 |
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Autore |
Hunter Tony <1943-, > |
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Titolo |
Receptor tyrosine kinases [[electronic resource] ] : function, families and evolution / / Tony Hunter |
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Pubbl/distr/stampa |
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London, : Henry Stewart Talks, 2007 |
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Descrizione fisica |
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1 online resource (1 streaming video file (53 min.) : color, sound) |
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Collana |
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Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease, , 2056-452X |
The world of hormones : molecular and physiological insights, , 2056-452X |
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Soggetti |
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Hormones |
Receptor Protein-Tyrosine Kinases |
Signal Transduction |
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Lingua di pubblicazione |
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Formato |
Videoregistrazione |
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Livello bibliografico |
Monografia |
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Note generali |
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Animated audio-visual presentation with synchronized narration. |
Title from title frames. |
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Nota di contenuto |
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Contents: History of protein phosphorylation -- Protein kinase bioinformatics -- History of tyrosine phosphorylation and functions of tyrosine kinases -- Genomic catalogues of protein kinases (kinomes) -- The human kinome -- The evolution of kinomes -- The human tyrosine kinase subfamily -- Receptor and nonreceptor tyrosine kinases -- Activation of receptor tyrosine kinases by ligand-induced dimerization -- Signal transduction pathways downstream of receptor tyrosine kinases -- Insulin and IOGF-1 receptor signaling via the mTOR pathway -- mTOR-S6 kinase feedback loop leading to downregulation of the IRS1 docking protein and insulin resistance -- History of Eph receptor tyrosine kinases and their ephrin ligands -- Bidirectional signaling via Eph-ephrin interactions on neighboring cells -- Simultaneous signaling by EphAs and ephrin As in motor neurons -- Compartmentalized signaling by receptor tyrosine kinases and their ligands through localization to discrete membrane domains -- Protein kinases and human disease -- Human cancer genes and protein kinases -- Protein kinases and phosphatases and cancer -- The long road to Gleevec. |
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