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1. |
Record Nr. |
UNINA9910719767203321 |
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Autore |
Edgerton Robert H. |
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Titolo |
Available energy and environmental economics / / Robert H. Edgerton |
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Pubbl/distr/stampa |
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Lexington, MA : , : Lexington Books, , 2023 |
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Descrizione fisica |
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Disciplina |
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Soggetti |
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Power resources - Environmental aspects |
Thermodynamics |
Power (Mechanics) |
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Materiale a stampa |
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Livello bibliografico |
Monografia |
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2. |
Record Nr. |
UNINA9910595075203321 |
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Autore |
Ruchala Marek |
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Titolo |
Novel Methods of Diagnostics of Thyroid and Parathyroid Lesions |
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Pubbl/distr/stampa |
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Descrizione fisica |
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1 online resource (148 p.) |
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Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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Thyroid nodular disease is one of the most frequent endocrine diseases. The prevalence of thyroid focal lesions detected by imaging techniques, according to studies on different populations, ranges from |
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10 to 70%. In a population of women over 50 years of age, approximately half of them will have a thyroid focal lesion. However, only 18% of thyroid nodules are diagnosed as malignant. Thyroid nodular disease is the most frequently diagnosed endocrine pathology, while thyroid cancer constitues the most common endocrine malignancy and is reponsible for about 67% of deaths due to neoplasms derived from endocrine organs. The incidence of thyroid cancer has risen by about 240% in the last three decades. Due to the increased availability of imaging techniques, recently, a rise in the detectability of thyroid cancer at the stage of microcarcinoma has been observed. Diagnostic and therapeutic decisions in patients with thyroid nodules require an interdisciplinary consensus between endocrinologists and physicians of other specialities (radiologists, pathologists, surgeons, oncologists). This book focuses on current trends in novel techniques of thyroid nodule diagnostics before they are implemented in the current guidelines on the management of thyroid nodular disease. |
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3. |
Record Nr. |
UNINA9910566462203321 |
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Autore |
Marchini Antonio |
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Titolo |
Oncolytic Virus Immunotherapy |
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Pubbl/distr/stampa |
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Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
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Descrizione fisica |
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1 online resource (366 p.) |
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Soggetti |
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Clinical and internal medicine |
Medicine and Nursing |
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Lingua di pubblicazione |
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Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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Dear Readers, Oncolytic Viruses (OV) are self-propagating agents that can selectively induce the lysis of cancer cells while sparing normal tissues. OV-mediated cancer cell death is often immunogenic and |
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triggers robust anticancer immune responses and immunoconversion of tumor microenvironments. This makes oncolytic virotherapy a promising new form of immunotherapy and OVs ideal candidates for combination therapy with other anticancer agents, including other immunotherapeutics. There are more than 40 OVs from nine different families in clinical development and many more at the preclinical stage. Each OV has its own unique characteristics, its pros and cons. Although herpes simplex virus is currently the lead clinical agent, a real champion among the OVs has not yet emerged, justifying the continuous development and optimization of these agents. This book, "Oncolytic Virus Immunotherapy", summarizes the state-of-the-art and gives a comprehensive overview of the OV arena with a particular focus on new trends, directions, challenges, and opportunities. |
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