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Record Nr. |
UNINA9910830054303321 |
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Titolo |
Somatostatin and its receptors [[electronic resource]] |
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Pubbl/distr/stampa |
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Chichester ; ; New York, : Wiley, 1995 |
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ISBN |
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1-282-13793-X |
9786612137938 |
0-470-51473-6 |
0-470-51474-4 |
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Descrizione fisica |
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1 online resource (285 p.) |
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Collana |
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Ciba Foundation symposium ; ; 190 |
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Altri autori (Persone) |
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Disciplina |
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591.192456 |
612.4/05 |
612.405 |
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Soggetti |
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Somatostatin |
Somatostatin - Receptors |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Symposium on Somatostatin and its receptors, held at the Ciba Foundation, London 12-14 July 1994. |
Editors: Derek J. Chadwick (organizer) and Gail Cardew. |
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Nota di bibliografia |
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Includes bibliographical references and indexes. |
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Nota di contenuto |
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SOMATOSTATIN AND ITS RECEPTORS; Contents; Participants; Introduction; Regulation of somatostatin gene transcription by cAMP; Processing and intracellular targeting of prosomatostatin-derived peptides: the role of mammalian endoproteases; Anatomical localization and regulation of somatostatin gene expression in the basal ganglia and its clinical implications; Molecular biology of somatostatin receptors; Characterization of somatostatin receptor subtypes; Regulation of somatostatin receptor mRNA expression; Transient expression of somatostatin receptors in the brain during development |
Expression of sstrl and sstr2 in rat hypothalamus: correlation with receptor binding and distribution of growth hormone regulatory peptidesInteraction of somatostatin receptors with G proteins and cellular effector systems; Somatostatin modulates voltage- dependent Ca2+ channels in GH3 cells via a specific Go splice variant; A tyrosine |
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phosphatase is associated with the somatostatin receptor1; Function and regulation of somatostatin receptor subtypes; Somatostatin receptors: clinical implications for endocrinology and oncology |
Somatostatin analogues and multiple receptors: possible physiological rolesFinal discussion; Summary; Appendix; Index of contributors; Subject index |
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Sommario/riassunto |
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This book describes a diverse analysis of the five somatostatin receptors; somatostatin gene regulation; promatostatin processing; mechanisms of signal transduction; and the design and use of somatostatin analogues, including their possible clinical implications. The book will provide a comprehensive summary of the cellular and molecular biology of somatostatin and its recently isolated receptors. The book will review the design and use of specific somatostatin analogues both biochemically to characterize the specific functions of somatostatin and clinically in the treatment of various tumors. |
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2. |
Record Nr. |
UNINA9910592984003321 |
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Autore |
Growiec Jakub |
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Titolo |
Accelerating Economic Growth : Lessons From 200,000 Years of Technological Progress and Human Development / / by Jakub Growiec |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022 |
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ISBN |
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9783031071959 |
9783031071942 |
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Edizione |
[1st ed. 2022.] |
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Descrizione fisica |
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1 online resource (181 pages) |
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Collana |
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Frontiers in Economic History, , 2662-978X |
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Disciplina |
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Soggetti |
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Economic history |
Economic development |
Technological innovations |
Technology |
History |
Economic History |
Economic Growth |
Economic Development, Innovation and Growth |
Economics of Innovation |
History of Technology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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Chapter 1. Introduction -- Part I. The Drive for Development -- Chapter 2. Enter local control -- Chapter 3. The force unleashed -- Part II. The Growth Mechanism -- Chapter 4. Hardware and software -- Chapter 5. Mechanization, automation and the labor market -- Chapter 6. Scale of operations -- Part III. The Great Leaps -- Chapter 7. Accelerating growth in the past -- Chapter 8. Accelerating growth in the future -- Part IV. Lessons for the Digital Era -- Chapter 9. Side effects of growth -- Chapter 10. Challenges of the digital era -- Chapter 11. Bracing for artificial general intelligence. |
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Sommario/riassunto |
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What made it possible for the human species to conquer the world, build a global digital economy, and still want more? What drives technological progress and economic growth in the long run and on a global scale? And how will technological progress, economic growth, and the overall prosperity of human civilization unfold in the future? This book sheds new light on these big questions by incorporating findings from physics, anthropology, psychology, history, philosophy, and computer science in a brand-new theory of economic growth. Looking back across the millennia, it identifies five major technological revolutions which have transformed humankind’s capacity to process energy and information—the cognitive, agricultural, scientific, industrial, and digital revolutions—and characterizes the new avenues of economic development which they have opened while also exponentially accelerating growth. |
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