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Record Nr. |
UNINA9910591045403321 |
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Autore |
Affolter Jehanne |
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Titolo |
ARCHAEDYN. Dynamique spatiale des territoires de la Préhistoire au Moyen Âge. Volume 1 / Estelle Gauthier, Murielle Georges-Leroy, Nicolas Poirier, Olivier Weller |
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Pubbl/distr/stampa |
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Besançon, : Presses universitaires de Franche-Comté, 2022 |
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ISBN |
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Descrizione fisica |
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1 online resource (346 p.) |
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Altri autori (Persone) |
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AllardPierre |
BrigandRobin |
CormierLaurie Tremblay |
DavidSophie |
FavoryFrançois |
FovetÉlise |
GabillotMaréva |
GauthierEstelle |
Georges-LeroyMurielle |
GiraudJessica |
Le GoffÉmeline |
LogelThierry |
MachutPierre |
MeyerNicolas |
NouvelPierre |
NuningerLaure |
PétrequinPierre |
PoirierNicolas |
WellerOlivier |
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Soggetti |
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Environmental Studies |
Archaeology |
archéologie |
modélisation |
analyse spatiale |
Préhistoire |
époque médiévale |
archaeology |
modelling |
spatial analysis |
Prehistory |
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Medieval Period |
arqueología |
modelización |
análisis especial |
Prehistoria |
ep medieval |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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L’objectif de cet ouvrage est de publier les résultats de la recherche lancée en 2004 dans l’ACI « Espaces et territoires » et poursuivie dans le cadre de l’ANR, en 2008. Ce programme de recherche a porté sur la dynamique spatiotemporelle des territoires, abordée dans la longue durée, du Néolithique au Moyen Âge, selon différentes thématiques et dans plusieurs microrégions de France et d’Europe. Ce volume présente les résultats de deux axes de recherche : la « dynamique des finages dans la longue durée » (Antiquité, Moyen Âge) et les « dynamiques de circulation et de consommation de produits bruts et manufacturés » (Néolithique, âge du bronze). The aim of this book is to publish the results of the research launched in 2004 in the ACI "Espaces et territoires" and continued in 2008 in the framework of the ANR (French National Research Agency). This research programme focused on the spatio-temporal dynamics of territories, approached over the long term, from the Neolithic period to the Middle Ages, according to different themes and in several micro-regions of France and Europe. This volume presents the results of two lines of research: the "dynamics of finishing in the long term" (Antiquity, Middle Ages) and the "dynamics of circulation and consumption of raw and manufactured products" (Neolithic, Bronze Age). El objetivo de este libro es publicar los resultados de la investigación iniciada en 2004 en la ACI "Espacios y Territorios" y continuada en el marco de la ANR en 2008. Este programa de investigación se centró en la dinámica espacio-temporal de los territorios, abordada a largo plazo, desde el período neolítico hasta la Edad Media, según diferentes temas y en varias microrregiones de Francia y Europa. Este volumen presenta los resultados de dos líneas de investigación: la "dinámica del acabado a largo plazo" (Antigüedad, Edad Media) y la "dinámica de la circulación y el consumo de materias primas y productos manufacturados" (Neolítico, Edad de Bronce). |
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2. |
Record Nr. |
UNINA9911020276303321 |
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Titolo |
Pathway analysis for drug discovery : computational infrastructure and applications / / edited by Anton Yuryev |
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Pubbl/distr/stampa |
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Hoboken, N.J., : John Wiley & Sons, c2008 |
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ISBN |
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9786611831264 |
9781281831262 |
1281831263 |
9780470399279 |
0470399279 |
9780470399262 |
0470399260 |
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Descrizione fisica |
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1 online resource (332 p.) |
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Collana |
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Wiley series on technologies for the pharmaceutical industry |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Drug development - Data processing |
DNA microarrays - Data processing |
Computational biology |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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PATHWAY ANALYSIS FOR DRUG DISCOVERY; CONTENTS; Preface; Contributors; 1 Introduction to Pathway Analysis; 2 Software Infrastructure and Data Model for Pathway Analysis; 3 Automatic Pathway Inference in Heterogeneous Biological Association Networks; 4 Algorithmic Basis for Pathway Visualization; 5 Pathway Analysis of High-Throughput Experimental Data; 6 Integrative Pathway Analysis of Disease Molecular Data; 7 Whole-Genome Expression Profiling of Papillary Serous Ovarian Cancer: Activated Pathways, Potential Targets, and Noise; 8 Mammalian Proteome and Toxicant Network Analysis |
9 Unraveling Mechanisms of Toxicity with the Power of Pathways: ToxWiz Tool as an Illustrative Example10 Impact of Chemistry Information on Pathway Analysis; 11 Propagation of Concentration Perturbations in Equilibrium Protein Binding Networks; 12 An Adaptive System Model of the Yeast Glucose Sensor System; 13 Present and Future of Pathway Analysis in Drug Discovery; Index |
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Sommario/riassunto |
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This book introduces drug researchers to the novel computational approaches of pathway analysis and explains the existing applications that can save time and money in the drug discovery process. It covers traditional computational methods and software for pathway analysis microarray, proteomics, and metabolomics. It explains pathway reconstruction of diseases and toxic states, pathway analysis in various phases, dynamic modeling of drug responses, and more. This is a core resource for drug discovery and pharmaceutical industry researchers, chemists, and biologists and for professionals in rela |
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