1.

Record Nr.

UNINA9910590083603321

Autore

Bhattacharjee Mrinal K.

Titolo

Chemistry of Antibiotics and Related Drugs / / by Mrinal K. Bhattacharjee

Pubbl/distr/stampa

Cham : , : Springer International Publishing : , : Imprint : Springer, , 2022

ISBN

9783031075827

9783031075810

Edizione

[2nd ed. 2022.]

Descrizione fisica

1 online resource (276 pages)

Collana

Chemistry and Materials Science Series

Disciplina

615.7922

Soggetti

Pharmaceutical chemistry

Clinical biochemistry

Microbiology

Pharmacy

Pharmacology

Medicinal Chemistry

Medical Biochemistry

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Includes index.

Nota di contenuto

Chapter 1: Introduction -- Chapter 2: Development of resistance to antibiotics -- Chapter 3: Antibiotics that inhibit cell wall synthesis -- Chapter 4: Antimetabolites: Antibiotics that inhibit nucleotide synthesis -- Chapter 5: Antibiotics that inhibit nucleic acid synthesis -- Chapter 6: Antibiotics that inhibit protein synthesis -- Chapter 7: Antibiotics that affect the membrane and other structural targets -- Chapter 8: Antifungals, Antimalarials and Antivirals -- Chapter 9: Alternative Approaches for Antibiotic Discovery -- Chapter 10: Global Action Plan and Antibiotic Stewardship.

Sommario/riassunto

This textbook builds on the success of the earlier edition, offering alternative strategies for discovering new antibiotics. It discusses how the various types of antibiotics and related drugs work to cure infections. Then it delves into the very serious matter of how bacteria are becoming resistant to these antibiotics. It also covers the global action plan on antimicrobial resistance from the World Health



Organization and discusses several Antibiotic Stewardship Programs adopted by agencies at local levels. Appropriate for a one-semester course at either the graduate or advanced undergraduate level, the book is self-contained and written in accessible language. It includes all necessary background biochemistry material and a discussion of the latest developments in the field of antibiotics. Original research works are frequently cited and experimental procedures and interpretation of results are emphasized.