1.

Record Nr.

UNINA9910821337803321

Autore

Barrington Robert <1966->

Titolo

Understanding corruption : how corruption works in practice / / Robert Barrington [and 3 others]

Pubbl/distr/stampa

Newcastle Upon Tyne : , : Agenda Publishing, , 2022

ISBN

1-78821-446-3

Descrizione fisica

xv, 263 pages

Altri autori (Persone)

David-BarrettElizabeth <1975->

PowerSam

HoughDan

Soggetti

corruption

case study

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references and index.

Sommario/riassunto

"Corruption takes many different forms and the systems that enable it are complex and challenging. To best understand corruption, one needs to examine how it operates in practice. Understanding Corruption tells the story of how corruption happens in the real world, illustrated through detailed case studies of the many different types of corruption that span the globe. Each case study follows a tried and tested analytical approach that provides key insights into the workings of corruption and the measures best used to tackle it. The case studies examined include examples of corporate bribery, political corruption, facilitation payments, cronyism, state capture, kleptocracy, asset recovery, offshore secrecy, reputation laundering and unexplained wealth, and actors include businesses, governments, politicians, governing bodies and public servants."--Publisher.



2.

Record Nr.

UNINA9910585945403321

Autore

Hussain Hidayat

Titolo

Theme Issue Honoring Prof. Dr. Ludger Wessjohann’s 60th Birthday: Natural Products in Modern Drug Discovery

Pubbl/distr/stampa

Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022

Descrizione fisica

1 online resource (360 p.)

Soggetti

Chemistry

Organic chemistry

Research and information: general

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

Nature continuously produces biologically useful molecules and provides humankind with life-saving drugs or therapies. Natural products (NPs) offer a vast, unique and fascinating chemical diversity and these molecules have evolved for optimal interactions with biological macromolecules. Moreover, natural products feature pharmacologically active pharmacophores which are pharmaceutically validated starting points for the development of new lead compounds. Over half of all approved (from 1981 to 2014) small-molecule drugs derived from NPs, including unaltered NPs, NPs synthetic derivatives and synthetic natural mimics, originated from a NPs pharmacophore or template. According to the FDA, NPs and their derivatives represent over one-third of all FDA-approved new drugs, in particular for anticancer/antibiotic lead compounds, which are remarkably enriched with NPs.