1.

Record Nr.

UNINA9910583092503321

Titolo

Neuroimaging . Part I / / volume editors, Joseph C. Masdeu, R. Gilberto Gonzalez

Pubbl/distr/stampa

Amsterdam, Netherlands : , : Elsevier, , 2016

©2016

ISBN

0-7020-4537-3

0-444-53485-7

Descrizione fisica

1 online resource (724 p.)

Collana

Handbook of Clinical Neurology ; ; Volume 135

Disciplina

616.804754

Soggetti

Nervous system - Imaging

Nervous system - Diseases - Imaging

Nervous System Diseases - diagnosis

Neuroimaging - methods

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references at the end of each chapters and index.

Nota di contenuto

Front Cover; Neuroimaging Part I; Copyright; Handbook of Clinical Neurology 3rd Series; Foreword; Preface; Contributors; Contents of Part I; Contents of Part II; Section 1: Neuroimaging methods; Chapter 1: Computed tomography imaging and angiography - principles; Computed tomography imaging and angiography: principles; Introduction; Principles; Noncontrast computed tomography (NCCT); Computed tomography angiography (CTA); CT/CTA selected technical-clinical pearls and pitfalls; Stroke - technical pearls and pitfalls; Nontraumatic intracranial hemorrhage - technical pearls and pitfalls

New developments and future directions; Dual-energy CT (DECT); Iterative reconstruction algorithms; References; Chapter 2: MR imaging: deconstructing timing diagrams and demystifying k-space; Introduction; Spin localization; Spin synchronization; Concept of an echo and k-space; A closer look at image space and k-space; Image detection and resolution considerations; Parallel imaging; A word about contrast; k-Space mapping strategies; Conclusions; References; Chapter 3: Volumetric and fiber-tracing MRI methods for gray and



white matter; Introduction; Brain macrostructure and microstructure

Quantitative volumetric brain analysis: segmentation; Structural segmentation methods; Imaging requirements; Sources of error; Analysis of brain segmentation results; Volumetric analysis; Surface analysis; Segmentation methods: practical approaches; Segmentation workflow; Brain segmentation systems; Applications of brain segmentation analysis; Evaluation of normal aging; Neurodegenerative disease; Alzheimer's disease; Frontotemporal dementia; Epilepsy; Quantitative analysis of white-matter integrity: diffusion and tractographic analysis; Introduction; Local diffusion analysis

Regional diffusion analysis: tractography; Diffusion MRI methods; Application of diffusion MRI in the evaluation of white-matter integrity; Local dMRI measures of white-matter integrity and injury; Local measures of dMRI in demyelinating disease; Local measures of dMRI changes in normal aging; Local measures of dMRI in neurodegenerative disease; Regional measures of white-matter integrity: tractography; Tractography: axonal patterning; Tractography: brain connectivity; Tractography: applications; Diffusion MRI and tractography methods: practical approaches

Diffusion MRI and tractography workflows; Diffusion MRI and tractography systems; Future developments; Summary; References; Chapter 4: Functional magnetic resonance imaging; Introduction; Physiologic principles underlying bold fMRI; Metabolic and hemodynamic signals are surrogates for neural activity; Neurometabolic and neurovascular coupling; Synaptic activity dominantly drives signaling-related energy metabolism; Classic model: neural activity is linearly coupled to CMRGlc, CMRO2, and CBF; Experiment: at rest neural activity is linearly coupled to CMRO2, CMRGlc, and CBF

Experiment: with activation, neural activity is nonlinearly coupled to CMRGlc and CBF, but nearly linearly coupled to CMRO2