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Record Nr. |
UNINA9910583012103321 |
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Titolo |
Biology and engineering of stem cell niches / / edited by Ajaykumar Vishwakarma, Jeffrey M. Karp |
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Pubbl/distr/stampa |
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London, England : , : Academic Press, , 2017 |
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©2017 |
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ISBN |
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Descrizione fisica |
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1 online resource (627 pages) : color illustrations |
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Disciplina |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references at the end of each chapters and index. |
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Nota di contenuto |
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I. Biology of stem cell niches and molecular mechanisms -- The need to study, mimic, and target stem cell niches -- Harnessing the biology of stem cells' niche -- Pluripotent stem cell microenvironment -- Regulation of hematopoietic stem cell dynamics by molecular niche signaling -- HSC niche: regulation of mobilization and homing -- Neuronal stem cells niches of the brain -- Cardiovascular stem cell niche -- Intestinal epithelial Lgr5+ stem cell niche and organoids -- The epithelial stem cell niche in skin -- The satellite cell niche in skeletal muscle -- The cancer stem cell niche -- Cellular senescence and stem cell niche -- Biochemical and physical cues in the stem cell niche directing cell fate -- Matrix chemistry controlling stem cell behavior -- Matrix growth factor and surface ligand presentation -- Effects of matrix mechanical forces and geometry on stem cell behavior -- Wettability effect on stem cell behavior -- Fluid flow control of stem cells with investigation of mechanotransduction pathways -- Hypoxia regulation of stem cell: mechanisms, biological properties, and applications -- III. Designing smart biomaterials to mimic and control stem cell niche -- Polymer design and development -- Design and development of ceramics and glasses -- Surface functionalization of biomaterials -- Biofunctional hydrogels for three-dimensional stem cell culture -- Technologies to engineer cell substrate mechanics in hydrogels -- Micro- and nanosurface patterning technologies -- Self- |
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assembled nanostructures (SANs) -- Biometric nanofibers as artificial stem cell niche -- IV. Bioengineering strategies to model synthetic stem cell niches -- Employing microfluidic devices to induce concentration gradients -- Engineering niches for embryonic and induced pluripotent stem cells -- Engineering niches for cardiovascular tissue regeneration -- Engineering niches for blood vessel regeneration -- Engineering niches for bone tissue regeneration -- Engineering vascular niche for bone tissue regeneration -- Engineering niches for cartilage tissue regeneration -- Engineering niches for stem and progenitor cell differentiation into immune cells -- Engineering niches for skin and wound healing -- Designing stem cell niche for liver development and regeneration -- Engineering the niche for intestinal regeneration. |
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