1.

Record Nr.

UNINA9910576868403321

Autore

Patricio Sánchez Arciniegas Jorge

Titolo

A Multiscale In Silico Study to Characterize the Atrial Electrical Activity of Patients With Atrial Fibrillation : A Translational Study to Guide Ablation Therapy

Pubbl/distr/stampa

Karlsruhe, : KIT Scientific Publishing, 2022

Descrizione fisica

1 electronic resource (162 p.)

Collana

Karlsruhe transactions on biomedical engineering

Soggetti

Electrical engineering

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

The atrial substrate undergoes electrical and structural remodeling during atrial fibrillation. Detailed multiscale models were used to study the effect of structural remodeling induced at the cellular and tissue levels. Simulated electrograms were used to train a machine-learning algorithm to characterize the substrate. Also, wave propagation direction was tracked from unannotated electrograms. In conclusion, in silico experiments provide insight into electrograms' information of the substrate.