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1. |
Record Nr. |
UNINA9910571775203321 |
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Autore |
Maraschio Nicoletta |
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Titolo |
Lingua italiana tra passato e futuro / / Nicoletta Maraschio |
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Pubbl/distr/stampa |
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Firenze : , : Firenze University Press, , 2015 |
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Descrizione fisica |
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1 online resource (68 pages) |
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Collana |
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Disciplina |
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Soggetti |
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Italian language - History |
Italian language - Dialects |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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This book outlines a short profile of Italy's linguistic history, and discusses some current problems related to globalization, the values of the mother tongue and multilingualism, and the need to re-found the Italian and European linguistic policy on a new basis. Contemporary Italian is a particularly stratified cultural asset in which, alongside the many new elements, one can grasp the clear and precious signs of a very strong connection with the past. Today, in the European scene, Italy indeed stands out for its accentuated multilingualism and the long duration of its national language. On the one hand, the extraordinary animal and plant biodiversity in the country corresponds to an extraordinary cultural and linguistic diversity; on the other, the Italians feel that the language used by Dante, Petrarca and Boccaccio still belongs to them, and has fundamental traits coinciding with their own. Such richness is particularly appreciated abroad (as evidenced by the growing demand for Italian speakers in the world) and deserves to be better acknowledged by the younger generations. It also deserves to be protected and valued with appropriate tools, starting with a decisive rethinking of the country's linguistic policy. |
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2. |
Record Nr. |
UNINA9910298280803321 |
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Titolo |
Targeted Genome Editing Using Site-Specific Nucleases : ZFNs, TALENs, and the CRISPR/Cas9 System / / edited by Takashi Yamamoto |
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Pubbl/distr/stampa |
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Tokyo : , : Springer Japan : , : Imprint : Springer, , 2015 |
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ISBN |
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Edizione |
[1st ed. 2015.] |
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Descrizione fisica |
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1 online resource (206 p.) |
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Disciplina |
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Soggetti |
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Transgenic organisms |
Developmental biology |
Cytology |
Animal genetics |
Plant genetics |
Transgenics |
Developmental Biology |
Cell Biology |
Animal Genetics and Genomics |
Plant Genetics and Genomics |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references at the end of each chapters. |
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Nota di contenuto |
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Preface -- Part 1 Basics of Genome Editing -- 1 Genome Editing Using Zinc-Finger Nucleases (ZFNs) and Transcription Activator-Like Effector Nucleases (TALENs) (Hiroshi Ochiai and Takashi Yamamoto)-. 2 CRISPR/Cas9: The Leading Edge of Genome Editing Technology (Tetsushi Sakuma and Takashi Yamamoto)-. Part 2 Genome Editing in Cultured Cells and Various Organisms -- 3 Editing in Cultured Human Cells: From Cell Lines to iPS Cells (Hongmei Lisa Li and Akitsu Hotta)-. 4 Genome Editing in Nematode (Takuma Sugi)-. 5 Highly Efficient Targeted Gene Disruption in the Silkworm, Bombyx mori, Using Genome Editing Tools (Takaaki Daimon)-. 6 Genome Editing in Sea |
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Urchin (Naoaki Sakamoto)-. 7 Genome Editing in Ascidians (Nicholas Treen and Yasunori Sasakura)-. 8 Genome Editing in Zebrafish and Medaka (Atsuo Kawahara, Taijiro Yabe, Satoshi Ansai, Shinji Takada, and Masato Kinoshita)-. 9 Genome Editing Using Site-Specific Nucleases in Amphibians (Ken-ichi T. Suzuki and Toshinori Hayashi)-. 10 Genome Editing in Mice Using CRISPR/CasĀ (Samantha AM Young, Mark Baker, and Masahito Ikawa)-. 11 Genome Editing in Mice Using TALENs (Tomomi Aida)-. 12 Engineered Nucleases Lead to Genome Editing Revolution in Rats (Kazuto Yoshimi, Takehito Kaneko, Birger Voigt, and Tomoji Mashimo)-. 13 Genome Editing in Higher Plants (Yuriko Osakabe and Keishi Osakabe). |
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Sommario/riassunto |
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This book serves as an introduction to targeted genome editing, beginning with the background of this rapidly developing field and methods for generation of engineered nucleases. Applications of genome editing tools are then described in detail, in iPS cells and diverse organisms such as mice, rats, marine invertebrates, fish, frogs, and plants. Tools that are mentioned include zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and CRISPR/Cas9, all of which have received much attention in recent years as breakthrough technologies. Genome editing with engineered nucleases allows us to precisely change the target genome of living cells and is a powerful way to control functional genes. It is feasible in almost all organisms ranging from bacteria to plants and animals, as well as in cultured cells such as ES and iPS cells. Various genome modifications have proven successful, including gene knockout and knock-in experiments with targeting vectors and chromosomal editing. Genome editing technologies hold great promise for the future, for example in biomedical research, clinical medicine, and generation of crops and livestock with desirable traits. A wide range of readers will find this book interesting, and with its focus on applications in a variety of organisms and cells, the book will be valuable for life scientists in all fields. |
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