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1. |
Record Nr. |
UNINA9911019450803321 |
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Titolo |
Adult epilepsy / / edited by Gregory D. Cascino and Joseph I. Sirven |
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Pubbl/distr/stampa |
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Chichester [England] : , : Wiley-Blackwell, , 2011 |
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©2011 |
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ISBN |
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9786613175359 |
9781119956327 |
1119956323 |
9780470975022 |
0470975024 |
9780470975039 |
0470975032 |
9781283175357 |
1283175355 |
9780470976197 |
0470976195 |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (xv, 307 p. ) : ill |
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Disciplina |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Seizure and epilepsy syndromes classification -- Epidemiology of seizure disorders -- The role of routine electroencephalography -- Neuroimaging in epilepsy -- Video-EEG monitoring data -- Etiologies of seizures -- The evaluation of nonepileptic paroxysmal events -- Mechanism of action of antiepileptic drugs -- Antiepileptic drugs : pharmacology, epilepsy indications, and selection -- Idiopathic generalized epilepsies -- Symptomatic generalized epilepsies -- Overview of diagnosis and medical treatment of partial epilepsies -- Medial temporal lobe epilepsy -- Substrate-directed epilepsy -- Non-substrate-directed partial epilepsy -- Surgical treatment. |
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Sommario/riassunto |
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Designed to provide a comprehensive but accessible introduction to epilepsy and seizure disorders, 'Adult Epilepsy' provides state-of-the-art information in a concise format useful to a wide audience, from neurology residents to epilepsy fellows and practitioners. |
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2. |
Record Nr. |
UNINA9910566471803321 |
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Autore |
Jeon Byeong Hwa |
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Titolo |
Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches |
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Pubbl/distr/stampa |
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Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022 |
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Descrizione fisica |
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1 online resource (368 p.) |
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Soggetti |
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Biotechnology |
Technology: general issues |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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Dear colleagues, This Special Issue, "Endothelial Dysfunction: From Pathophysiology to Novel Therapeutic Approaches", focuses on the pathophysiology of endothelial dysfunction, new biomarkers for endothelial dysfunction related to cardiovascular disorders or tumors, and novel therapeutic approaches for endothelial dysfunctions. Vascular endothelium is an active tissue and plays a crucial role in the maintenance of vascular homeostasis. Chronic exposure to risk factors, such as hypertension, high cholesterolemia, or oxidative stress, induces endothelial dysfunctions and results in a loss of endothelial integrity, smooth muscle cell proliferation, and macrophage recruitment. The pathophysiology of endothelial dysfunction (ED) is complex and multi-factorial factors are involved, such as oxidative stress or chronic inflammation. The primary prevention of cardiovascular risk factors and endothelial dysfunctions, as well as the early detection of or molecular imaging techniques for endothelial dysfunction, helps to prevent the development of cardiovascular |
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disorders. Novel therapeutic approaches or drug delivery systems for endothelial dysfunctions have had promising beneficial effects in preclinical or clinical levels by affecting the progression of atherosclerotic changes, tumor angiogenesis, and host-immune reactions near tumor environments. |
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