1.

Record Nr.

UNINA9910566469503321

Autore

Kahn Michael

Titolo

Targeting Wnt Signaling in Cancer: Opportunities Abound If We Can Avoid the Sword of Damocles

Pubbl/distr/stampa

Basel, : MDPI - Multidisciplinary Digital Publishing Institute, 2022

Descrizione fisica

1 electronic resource (298 p.)

Soggetti

Medicine

Pharmacology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

Dysregulation of Wnt signaling is known to be associated with various cancers. As such, identification of novel Wnt pathway targets in cancer and better characterization of already-known targets present exciting, emerging opportunities for cancer treatment. In this Special Issue, we feature papers which discuss the role of Wnt signaling and associated targets in cancer metabolism, tumor immune response, and tumor microenvironment. Papers discussing a range of Wnt-mediated cancers, including those of the colon, liver, pancreas, synovium, bladder, etc., are included.