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1. |
Record Nr. |
UNINA9910557793503321 |
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Autore |
Rein Theo |
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Titolo |
Molecular Psychiatry |
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Pubbl/distr/stampa |
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Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
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Descrizione fisica |
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1 online resource (288 p.) |
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Soggetti |
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Medicine and Nursing |
Mental health services |
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Lingua di pubblicazione |
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Materiale a stampa |
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Livello bibliografico |
Monografia |
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The book highlights important aspects of Molecular Psychiatry, including molecular mechanisms, animal models, biomarkers, advanced methods, drugs and antidepressant response, as well as genetics and epigenetics. Molecular mechanisms are a vital part of the search for the biological basis of psychiatric disorders, providing molecular hints that can later be tested as biomarkers or targets for drug development. Animal models represent a commonly used approach to aid in this bench-to-bed translation; the examples here are social defeat stress and the Roman High-Avoidance (RHA) and the Roman Low-Avoidance (RLA) rats. For biomarkers, psychiatric disorders pose a particular challenge due to the tissue specificity of many currently investigated biomarkers; i.e., not all blood-based measures directly represent changes in the brain. The Ebook includes five articles focused on the challenges of identifying clinically and biologically relevant biomarkers for psychiatric disorders. Scientific progress typically is fostered by the development of new methods. The application of machine learning methods for the proper analysis of Big Data and induced pluripotent stem cells are examples outlined in this Ebook. Furthermore, three articles are devoted to the understanding of the mechanisms of actions of existing drugs with the ultimate goal of identifying ways to predict treatment response in patients. Finally, three articles deepen the insight |
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into the genetics and epigenetics of psychiatric disorders. |
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2. |
Record Nr. |
UNINA9910557526303321 |
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Autore |
Diaconu Camelia |
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Titolo |
Interdisciplinary Medicine |
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Pubbl/distr/stampa |
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Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021 |
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Descrizione fisica |
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1 online resource (282 p.) |
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Livello bibliografico |
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Sommario/riassunto |
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Dear Colleagues, The rapidly changing field of medicine and healthcare is increasingly adopting scientific and technological innovations, making interdisciplinary collaborations especially important. In this context, medical disciplines are becoming increasingly interlinked with other specialities and fields. A more interdisciplinary approach to the patient is needed, especially for complex patients with numerous comorbidities, most of whom are usually elderly and fragile. The greatest challenges to human health lie at the intersection of different medical fields. An interdisciplinary medical team is increasingly necessary with the rapid expansion of medical knowledge. Given the importance of interdisciplinarity in the field of medicine and research, the international journal Medicina-Lithuania has launched this Special Issue. The Special Issue has attracted the interest of different groups of researchers, and very interesting articles from different countries. Reviews or original articles dealing with interdisciplinary medical problems, as well as articles providing an up-to-date overview of the diagnostic protocols and treatments for patients with multiple comorbidities have been published. I thank all the authors for sharing their research and wish all readers a fruitful and stimulating read! Assoc. Prof. Dr. Camelia |
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