1.

Record Nr.

UNINA9910797714103321

Autore

Coates A. J (Anthony Joseph), <1940->

Titolo

The ethics of war / / A.J. Coates

Pubbl/distr/stampa

Manchester : , : Manchester University Press, , 1997

Baltimore, Md. : , : Project MUSE, , 2017

©1997

ISBN

1-78499-602-5

9781784996659

1-78499-665-3

9780719040450

9780719040467

Descrizione fisica

1 online resource (403 pages) : illustrations

Disciplina

172/.42

Soggetti

Just war doctrine

War - Moral and ethical aspects

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references (p. [295]-304) and index.

Nota di contenuto

Front matter -- Contents -- Preface to the second edition -- Acknowledgements -- Introduction to the second edition -- Introduction to the first edition -- Part I: Images of war -- 1 Realism -- 2 Militarism -- 3 Pacifism -- 4 The just war -- Part II: Principles and concepts of the just war -- 5 Legitimate authority -- 6 Just cause -- 7 Proportionality and the recourse to war -- 8 Last resort -- 9 Proportionality and the conduct of war -- 10 Noncombatant immunity -- 11 Peacemaking -- Part III: Terrorism and counterterrorism -- 12 On defining terrorism -- 13 Terrorism -- 14 Counterterrorism -- References -- Index

Sommario/riassunto

The ethics of war explores the moral limits and possibilities of conflict. The argument proceeds from a just war standpoint which balances rules or principles against the moral capacities and dispositions of belligerents and the particular circumstances in which they act. In this enlarged second edition, a new introduction reflects on the impact of changes to just war thinking and to the practice of war since the book's



original publication. The common criticism that traditional just war theory is incoherent, outmoded and in need of radical revision is resisted, and instead, a case is made for an ethics of war rooted in the historic tradition of just war. The concept of just war is compared with realism, militarism and pacifism; the principles of just recourse and just conduct are examined with the aid of real life examples; and a new third part addresses some of the ethical problems raised by terrorism and counterterrorism.

2.

Record Nr.

UNINA9910557761103321

Autore

Dansette Patrick M

Titolo

Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity 2.0

Pubbl/distr/stampa

Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2021

Descrizione fisica

1 online resource (286 p.)

Soggetti

Research and information: general

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

This book, "Cytochromes P450: Drug Metabolism, Bioactivation and Biodiversity", presents five papers on human cytochrome P450 (CYP) and P450 reductase, three reviews on the role of CYPs in humans and their use as biomarkers, six papers on CYPs in microorganisms, and one study on CYP in insects.  The first paper reports the in silico modeling of human CYP3A4 access channels. The second uses structural methods to explain the mechanism-based inactivation of CYP3A4 by mibefradil, 6,7-dihydroxy-bergamottin, and azamulin. The third article compares electron transfer in CYP2C9 and CYP2C19 using structural and biochemical methods, and the fourth uses kinetic methods to study electron transfer to CYP2C8 allelic mutants. The fifth article characterizes electron transfer between the reductase and CYP using in silico and in vitro methods, focusing on the conformations of



the reductase.  Then, two reviews describe clinical implications in cardiology and oncology and the role of fatty acid metabolism in cardiology and skin diseases. The second review is on the potential use of circulating extracellular vesicles as biomarkers.  Five papers analyze the CYPomes of diverse microorganisms: the Bacillus genus, Mycobacteria, the fungi Tremellomycetes, Cyanobacteria, and Streptomyces. The sixth focuses on a specific Mycobacterium CYP, CYP128, and its importance in M. tuberculosis.  The subject of the last paper is CYP in Sogatella furcifera, a plant pest, and its resistance to the insecticide sulfoxaflor.