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1. |
Record Nr. |
UNISA996394983603316 |
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Titolo |
By the King. A proclamation for recalling of commissions at sea [[electronic resource]] |
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Pubbl/distr/stampa |
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London, : Printed by John Bill and Christopher Barker, printers to the Kings most excellent Majesty, 1660 |
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Descrizione fisica |
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Altri autori (Persone) |
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Charles, King of England, <1630-1685.> |
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Soggetti |
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Commissions of array - England |
Great Britain History, Naval Stuarts, 1603-1714 Early works to 1800 |
Great Britain Politics and government 1649-1660 Early works to 1800 |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Dated at end: Given at our court at Whitehal, the fifteenth of June, in the twelfth year of his Majesties reign, 1660. |
Arms 61; Steele notation: and hurt his. |
Annotation on Thomason copy: "June 16.". |
Two copies of this item are filmed consecutively at reel C18:1[42]-[43]. |
Reproduction of original in the British Library. |
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2. |
Record Nr. |
UNINA9910557746603321 |
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Autore |
Leitão Jorge H |
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Titolo |
Microbial Virulence Factors |
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Pubbl/distr/stampa |
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Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020 |
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Descrizione fisica |
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1 online resource (400 p.) |
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Soggetti |
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Biology, life sciences |
Research and information: general |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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Microbial virulence factors encompass a wide range of molecules produced by pathogenic microorganisms, enhancing their ability to evade their host defenses and cause disease. This broad definition comprises secreted products such as toxins, enzymes, exopolysaccharides, as well as cell surface structures such as capsules, lipopolysaccharides, glyco- and lipoproteins. Intracellular changes in metabolic regulatory networks, governed by protein sensors/regulators and non-coding regulatory RNAs, are also known to contribute to virulence. Furthermore, some secreted microbial products have the ability to enter the host cell and manipulate their machinery, contributing to the success of the infection. The knowledge, at the molecular level, of the biology of microbial pathogens and their virulence factors is central in the development of novel therapeutic molecules and strategies to combat microbial infections. The present collection comprises state of the art research and review papers on virulence factors and mechanisms of a wide range of bacterial and fungal pathogens for humans, animals, and plants, thus reflecting the impact of microorganisms in health and economic human activities, and the importance of the topic. |
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