1.

Record Nr.

UNINA9910557565803321

Autore

Eun-Hyung Lee F

Titolo

Advances in Plasma Cells in Health and Disease

Pubbl/distr/stampa

Frontiers Media SA, 2020

Descrizione fisica

1 online resource (139 p.)

Soggetti

Immunology

Medicine and Nursing

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact



2.

Record Nr.

UNINA9910896531203321

Titolo

Chemistry and Biology of O-GlcNAcylation / / edited by Wen Yi

Pubbl/distr/stampa

Singapore : , : Springer Nature Singapore : , : Imprint : Springer, , 2024

ISBN

981-9748-64-X

Edizione

[1st ed. 2024.]

Descrizione fisica

1 online resource (178 pages)

Disciplina

572.68

Soggetti

Medicine - Research

Biology - Research

Cytology

Biomedical Research

Cell Biology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

Chapter 1. Chemical tools for decoding the functions of O-GlcNAcylation -- Chapter 2. Profiling O-GlcNAcylation with mass spectrometry -- Chapter 3. O-GlcNAcylation and cell metabolism -- Chapter 4. O-GlcNAcylation and transcriptional regulation and epigenetics -- Chapter 5. O-GlcNAcylation and signal transduction -- Chapter 6. O-GlcNAcylation and stem cells -- Chapter 7. O-GlcNAcylation and immune regulation -- Chapter 8. O-GlcNAcylation and neuronal development, neurodegeneration and neurological disorders.

Sommario/riassunto

O-linked N-acetylglucosamine (O-GlcNAc) is a prevalent post-translational modification of numerous intracellular proteins. This modification has recently emerged as a key regulator of various important biological processes, including gene transcription, stress response, metabolic homeostasis, and immune regulation. Given the critical role of O-GlcNAc in normal physiology, increasing evidence has now demonstrated that deregulation of O-GlcNAc is closely associated with the development and progression of various diseases, including neurodegeneration, cardiovascular disease, and cancer. This book provides a comprehensive overview of the current progress and understanding of this modification in biology, and likely provides new



research directions in the future.