1.

Record Nr.

UNINA9910557291103321

Autore

Ferraris Davide Maria

Titolo

Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment

Pubbl/distr/stampa

Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020

Descrizione fisica

1 online resource (128 p.)

Soggetti

Biology, life sciences

Research & information: general

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis (MTB) and it represents a persistent public health threat for a number of complex biological and sociological reasons. According to the most recent Global Tuberculosis Report (2019) edited by the World Health Organization (WHO), TB is considered the ninth cause of death worldwide and the leading cause of mortality by a single infectious agent, with the highest rate of infections and death toll rate mostly concentrated in developing and low-income countries. We present here the editorial section to the Special Issue entitled "Mycobacterium tuberculosis Pathogenesis, Infection Prevention and Treatment" that includes 7 research articles and a review. The scientific contributions included in the Special Issue mainly focus on the characterization of MTB strains emerging in TB endemic countries as well as on multiple mechanisms adopted by the bacteria to resist and to adapt to antitubercular therapies.



2.

Record Nr.

UNINA9910557787803321

Autore

Kurlyandskaya Galina V

Titolo

Biosensors with Magnetic Nanocomponents

Pubbl/distr/stampa

Basel, Switzerland, : MDPI - Multidisciplinary Digital Publishing Institute, 2020

Descrizione fisica

1 online resource (170 p.)

Soggetti

History of engineering and technology

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

The selective and quantitative detection of biocomponents is greatly requested in biomedical applications and clinical diagnostics. Many traditional magnetic materials are not suitable for the ever-increasing demands of these processes. The push for a new generation of microscale sensors for bioapplications continues to challenge the materials science community to develop novel nanostructures that are suitable for such purposes. The principal requirements of a new generation of nanomaterials for sensor applications are based on well-known demands: high sensitivity, small size, low power consumption, stability, quick response, resistance to aggressive media, low price, and easy operation by nonskilled personnel. There are different types of magnetic effects capable of creating sensors for biology, medicine, and drug delivery, including magnetoresistance, spin valves, Hall and inductive effects, and giant magnetoimpedance. The present goal is to design nanomaterials both for magnetic markers and sensitive elements as synergetic pairs working in one device with adjusted characteristics of both materials. Synthetic approaches using the advantages of simulation methods and synthetic materials mimicking natural tissue properties can be useful, as can the further development of modeling strategies for magnetic nanostructures.