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Record Nr. |
UNINA9910557255903321 |
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Autore |
Gaspar Joana M |
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Titolo |
Obesity and Diabetes: Implications for Brain-Immunometabolism |
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Pubbl/distr/stampa |
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Descrizione fisica |
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1 online resource (204 p.) |
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Soggetti |
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Neurosciences |
Science: general issues |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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Obesity is a major worldwide health problem, reached epidemic proportions that affects both developed and developing countries. Obesity increases the risk for a wide metabolic conditions including type 2 diabetes. Additionally, a relationship between obesity, diabetes and cognitive function, as well as risk of dementias have come to attention. The link between these pathologies is the activation of the inflammatory process. Obesity is considered as a chronic low grade inflammatory disease that affects numerous tissues including the brain. The consumption of large amounts of dietary fats, particularly saturated fatty acids can impair hypothalamic neuronal metabolism and circuitries that control whole-body energy homeostasis, consequently leading to obesity. Homeostatic control of brain metabolism is essential for neuronal activity. Neuroendocrine signals play a major role in the regulation of brain metabolism and also peripheral energy balance. Brain inflammation is a major cause for brain metabolic dysfunction and it is known to impair the control of whole-body energy homeostasis and also brain activity in several metabolic and neurodegenerative disorders. Metabolic diseases, inflammation, and brain diseases are likely linked, however a clear mechanistic understanding has remained elusive. This Research Topic collects articles on the neurometabolic changes in the brain induced by inflammatory processes associated with obesity and chronic metabolic |
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2. |
Record Nr. |
UNINA9910955505503321 |
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Titolo |
Intersubjectivity and objectivity in Adam Smith and Edmund Husserl : a collection of essays / / Christel Fricke, Dagfinn Føllesdal (eds) |
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Pubbl/distr/stampa |
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Frankfurt, : Ontos Verlag, 2012 |
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ISBN |
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3-86838-145-7 |
3-11-032594-2 |
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Descrizione fisica |
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1 online resource (319 p.) |
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Collana |
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Philosophische Forschung ; ; Bd. 8 |
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Altri autori (Persone) |
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FrickeChristel |
FøllesdalDagfinn |
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Disciplina |
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Soggetti |
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Intersubjectivity |
Objectivity |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references. |
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Nota di contenuto |
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Frontmatter -- Contents -- Preface -- Introduction -- 1. A Phenomenological Approach to Intersubjectivity in the Sciences / Kjosavik, Frode -- 2. Husserl's Approaches to Volitional Consciousness / Peucker, Henning -- 3. "We-Subjectivity": Husserl on Community and Communal Constitution / McIntyre, Ronald -- 4. Husserl on Understanding Persons / Beyer, Christian -- 5. Imagination and Appresentation, Sympathy and Empathy in Smith and Husserl / Drummond, John J. -- 6. Mengzi (Mencius), Adam Smith and Edmund Husserl on Sympathy and Conscience / Kern, Iso -- 7. Overcoming Disagreement - Adam Smith and Edmund Husserl on Strategies of Justifying Descriptive and Evaluative Judgments / Fricke, Christel -- 8. Intersubjectivity and Moral Judgment in Adam Smith's Theory of Moral Sentiments / Brown, Vivienne -- 9. Sympathy in Hume and Smith: A Contrast, Critique, and Reconstruction / Fleischacker, Sam -- Contributors |
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Sommario/riassunto |
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Can we have objective knowledge of the world? Can we understand |
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what is morally right or wrong? Yes, to some extent. This is the answer given by Adam Smith and Edmund Husserl. Both rejected David Hume's skeptical account of what we can hope to understand. But they held his empirical method in high regard, inquiring into the way we perceive and emotionally experience the world, into the nature and function of human empathy and sympathy and the role of the imagination in processes of intersubjective understanding. The challenge is to overcome the natural constraints of perceptual and emotional e |
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