Plasmids : biology and impact in biotechnology and discovery / / edited by Marcelo Tolmasky, Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University, Fullerton, and Juan Carlos Alonso, Centro Nacional de Biotecnología, CSIC, Departamento de Biotecnología Microbiana, Madrid, Spain

• Record Nr.: UNINA9910555296403321
• Pubbl/distr/stampa: Washington, District of Columbia : , : ASM Press, , 2015; ©2015
• ISBN: 1-68367-339-5; 1-68367-097-3; 1-55581-898-6
• Descrizione fisica: 1 online resource (720 p.)
• Disciplina: 572.8/69
• Soggetti: Plasmids
• Lingua di pubblicazione: Inglese
• Formato: Materiale a stampa
• Livello bibliografico: Monografia
• Note generali: Description based upon print version of record.
• Nota di bibliografia: Includes bibliographical references and index.
• Nota di contenuto: ""Cover ""; ""Half Title ""; ""Title Page ""; ""Copyright ""; ""Dedication ""; ""Contents""; ""Contributors""; ""Preface""; ""I. Introduction""; ""Chapter 1: Historical Events That Spawned the Field of Plasmid Biology""; ""INTRODUCTION""; ""BIRTH OF THE FIELD OF PLASMID BIOLOGY""; ""EARLY STRUCTURAL STUDIES AND GENETIC MAPPING OF PLASMIDS""; ""RECOGNITION OF PLASMID REPLICATION AND PARTITIONING SYSTEMS""; ""LANDMARKS LEADING TO PLASMID-MEDIATED CONJUGATIVE TRANSFER""; ""FUNCTIONAL ATTRIBUTES REQUIRED FOR PLASMID PERSISTENCE AND SURVIVAL""; ""RECONSTRUCTION OF PLASMIDS FOR BIOTECHNOLOGY AND BIOMEDICAL APPLICATIONS""""CONCLUSION AND FUTURE OF PLASMID BIOLOGY""; ""References""; ""II. Plasmid Replication Systems and Their Control""; ""Chapter 2: Iteron Plasmids""; ""INTRODUCTION""; ""STRUCTURE OF THE ORIGIN OF REPLICATION INITIATION""; ""Rep PROTEIN STRUCTURE""; ""MECHANISM OF ITERON PLASMID DNA REPLICATION INITIATION""; ""CONTROL MECHANISMS OF REPLICATION IN ITERON-CONTAINING PLASMIDS""; ""CONCLUSIONS""; ""References""; ; ""Chapter 3: Mechanisms of Theta Plasmid Replication""; ""INTRODUCTION""; ""REPLICATION INITIATION""; ""THETA PLASMID REPLICATION""""COMPARISON OF THE THETA AND STRAND-DISPLACEMENT MODES OF PLASMID REPLICATION""; ""REGULATION OF REPLICATION INITIATION""; ""CONCLUDING REMARKS""; ""References""; ""Chapter 4: Plasmid Rolling-Circle Replication""; ""GENERAL ASPECTS OF PLASMID ROLLING-CIRCLE REPLICATION""; ""THE DOUBLE-STRAND ORIGIN""; ""THE REPLICATION INITIATOR REP PROTEINS""; ""CONTROL OF RCR""; ""THE SINGLE-STRAND ORIGIN""; ""HOST PROTEINS INVOLVED IN RCR""; ""CONCLUDING REMARKS""; ""References""; ""Chapter 5: Replication and Maintenance of Linear Phage-Plasmid N15""; ""THE FAMILY OF LINEAR N15-LIKE PHAGE-PLASMIDS""""ORGANIZATION OF THE GENOMES""; ""CONTROL OF LYSOGENY AND PLASMID REPLICATION""; ""PLASMID PROPHAGE PARTITIONING SYSTEM""; ""GENERATION OF COVALENTLY CLOSED TELOMERES""; ""REPLICATION MECHANISM""; ""BIOTECHNOLOGICAL APPLICATIONS""; ""ORIGIN OF N15-LIKE PHAGE-PLASMIDS""; ""References""; ""Chapter 6: Plasmid Replication Control by Antisense RNAs""; ""INTRODUCTION""; ""ANTISENSE-RNA-MEDIATED TRANSCRIPTIONAL ATTENUATION: THE inc18 AND THE pT181 FAMILIES""; ""INHIBITION OF PRIMER FORMATION: THE ColE1 REPLICON""; ""INHIBITION OF PSEUDOKNOT FORMATION: THE IncI /IncB CASE""""TRANSLATIONAL INHIBITION""; ""THE ColE2 CASE""; ""COMPARISON BETWEEN REGULATORY sRNAs INVOLVED IN PLASMID REPLICATION CONTROL AND THOSE ACTING ON CHROMOSOMALLY ENCODED TARGETS""; ""References""; ""Chapter 7: Topological Behavior of Plasmid DNA""; ""TOPOLOGY OF CIRCULAR DNA""; ""ENZYMES OF DNA TOPOLOGY""; ""DYNAMIC TOPOLOGICAL EQUILIBRIUM""; ""SUPERCOIL-SENSITIVE DNA STRUCTURE""; ""CONSTRAINED AND UNCONSTRAINED PLASMID TOPOLOGY IN VIVO""; ""PROTEINS THAT CONSTRAIN TOPOLOGY IN E. COLI""; ""VARIATION OF CONSTRAINED AND UNCONSTRAINED SUPERCOILING IN VIVO ""