1.

Record Nr.

UNINA9910555074303321

Autore

Machin David <1939->

Titolo

Sample sizes for clinical, laboratory and epidemiology studies / / David Machin, [and three others]

Pubbl/distr/stampa

Hoboken, New Jersey : , : Wiley, , [2018]

ISBN

1-118-87493-5

1-118-87492-7

1-118-87490-0

Edizione

[Fourth edition.]

Descrizione fisica

1 online resource (409 pages)

Collana

THEi Wiley ebooks.

Disciplina

615.5072/4

Soggetti

Clinical trials

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Ranking the Multiple Endpoints2.5 Repeated Significance Tests; Bonferroni Correction; 2.6 Epidemiological Studies; 2.7 The Protocol and Publication; 2.8 Ethical Issues and Sample Size; References; Chapter 3 Binary Outcomes; 3.1 Introduction; 3.2 Comparing Proportions; Effect Size; Analysis; χ2 Test; Fisher's Exact Test; 3.3 One Proportion Known; χ2 Test; 3.4 Bibliography; 3.5 Examples and Use of the Tables; Table 3.1 and Equations 3.2 and 3.3; Table 3.1 and Equations 3.2, 3.3, 3.4 and 3.5; Equations 3.2 and 3.5; Table 3.2 and Equations 3.1, 3.2, 3.3 and 3.4; Equations 3.1, 3.3 and 3.4.

Sommario/riassunto

"Sample Size Tables for Clinical Studies provides the statistical tools - equations, formulae and numerical tables - statisticians and researchers need to design and plan valid clinical studies and to accurately analyse publishable results. It explains the sample size considerations that are important when designing and planning any type of clinical study. It clearly outlines the methodologies employed, within the context of clinical studies and trials, and provides relevant practical examples. Each chapter provides and explains sets of sample size tables. They also include Bibliography and References sections directed towards further guidance on the principles discussed and more detailed explanations"--Provided by publisher.