1.

Record Nr.

UNINA9910555060203321

Titolo

Cotes' lung function / / edited by Robert L. Maynard

Pubbl/distr/stampa

Hoboken, New Jersey : , : John Wiley & Sons, Inc., , [2020]

©2020

ISBN

1-118-59732-X

1-118-59733-8

1-118-59730-3

Edizione

[Seventh edition.]

Descrizione fisica

1 online resource (809 pages)

Disciplina

611.24

Soggetti

Lungs

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

How we came to have lungs and how our understanding of lung function has developed. -- Getting started. -- Development and functional anatomy of the respiratory system. -- Body size and anthropometric measurements. -- Numerical interpretation of physiological variables. -- Basic terminology and gas laws. -- Basic equipment and measurement techniques. -- Respiratory surveys : epidemiological methods. -- The application of analytical technique applied to expired air as a means of monitoring airway and lung function -- Anatomy and function of the thoracic cage and respiratory muscles. -- Lung volumes. -- Lung and chest wall elasticity. -- Forced ventilation volumes and flows. -- Theory and measurement of respiratory resistances. -- The control of airway function and the assessment of airway calibre -- Distribution, measurement and inter-relationship between ventilation and perfusion -- Transfer of gases into the blood of alveolar capillaries. -- Transfer factor for CO and NO. -- Oxygen : uptake and transport in the blood -- Carbon dioxide : gas exchange and acid base balance -- Control of respiration. -- Breathing sensation -- Breathing function in newborn babies -- Normal lung function from childhood to old age. -- Reference values for lung function in white (Caucasian) children and adults. -- Reference values for lung function in non-Caucasians. -- Physiology of exercise and



effects of lung disease on performance. -- Exercise testing and interpretation, including reference values. -- Assessment of exercise limitation, disability and residual ability. -- Exercise in children -- Breathing during sleep and its investigation. -- Hypobaria, high altitude, aviation physiology and medicine -- Immersion in water, hyperbaria and hyperoxia including oxygen therapy. -- Effects of cold and heat on the lung. -- Strategies for assessment of lung function. -- Patterns of abnormal lung function in lung disease -- Lung function patterns in asthma, chronic obstructive pulmonary disease and lung fibrosis. -- Lung function in specific respiratory and systemic diseases: a compendium. -- Pulmonary rehabilitation. -- Lung function in relation to surgery, anaesthesia and intensive care.

Sommario/riassunto

"The only text to cover lung function assessment from first principles including methodology, reference values and interpretation. Editors are amongst the world's leading authorities on lung function. Text completely re-written in a contemporary style: includes user-friendly equations and more diagrams. New material covering the latest advances in the treatment of lung function, including a stronger clinical and practical bias and more on new techniques and equipment"--



2.

Record Nr.

UNINA9910817010203321

Titolo

Boronic acids . Volume 2 Preparation and applications in organic synthesis, medicine and materials / / edited by Dennis G. Hall ; with a foreword by Akira Suszuki

Pubbl/distr/stampa

Weinheim : , : Wiley-VCH, , [2011]

ISBN

9786613916495

9781283604048

1283604043

9783527332144

3527332146

9783527639342

3527639349

9783527639328

3527639322

Edizione

[Second completely revised edition]

Descrizione fisica

1 online resource (729 pages)

Disciplina

547.05671

Soggetti

Àcids orgànics

Compostos organobòrics

Organic acids

Organoboron compounds

Organic acids - Therapeutic use

Organoboron compounds - Therapeutic use

Organic acids - Synthesis

Organoboron compounds - Synthesis

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Description based upon print version of record.

Nota di bibliografia

Includes bibliographical references and index.

Nota di contenuto

Boronic Acids: Preparation and Applications in Organic Synthesis, Medicine and Materials; Foreword; Contents to Volume 1; Contents to Volume 2; Preface; List of Contributors; 1 Structure, Properties, and Preparation of Boronic Acid Derivatives: Overview of Their Reactions and Applications; 1.1 Introduction and Historical Background; 1.2



Structure and Properties of Boronic Acid Derivatives; 1.2.1 General Types and Nomenclature of Boronic Acid Derivatives; 1.2.2 Boronic Acids; 1.2.2.1 Structure and Bonding; 1.2.2.2 Physical Properties and Handling; 1.2.2.3 Safety Considerations

1.2.2.4 Acidic Character1.2.2.5 Chemical Stability; 1.2.3 Boronic Acid Derivatives; 1.2.3.1 Boroxines (Cyclic Anhydrides); 1.2.3.2 Boronic Esters; 1.2.3.3 Acyloxy- and Diacyloxyboronates; 1.2.3.4 Dialkoxyboranes and Other Heterocyclic Boranes; 1.2.3.5 Diboronyl Esters; 1.2.3.6 Azaborolidines and Other Boron-Nitrogen Heterocycles; 1.2.3.7 Dihaloboranes and Dihydroalkylboranes; 1.2.3.8 Trifluoro- and Trihydroxyborate Salts; 1.3 Preparation of Boronic Acids and Their Esters; 1.3.1 Arylboronic Acids; 1.3.1.1 Electrophilic Trapping of Arylmetal Intermediates with Borates

1.3.1.2 Transmetalation of Aryl Silanes and Stannanes1.3.1.3 Coupling of Aryl Halides with Diboronyl Reagents; 1.3.1.4 Direct Boronation by Transition Metal-Catalyzed Aromatic C-H Functionalization; 1.3.1.5 Cycloadditions of Alkynylboronates; 1.3.1.6 Other Methods; 1.3.2 Diboronic Acids; 1.3.3 Heterocyclic Boronic Acids; 1.3.4 Alkenylboronic Acids; 1.3.4.1 Electrophilic Trapping of Alkenylmetal Intermediates with Borates; 1.3.4.2 Transmetalation Methods; 1.3.4.3 Transition Metal-Catalyzed Coupling between Alkenyl Halides/ Triflates and Diboronyl Reagents; 1.3.4.4 Hydroboration of Alkynes

1.3.4.5 Alkene Metathesis1.3.4.6 Diboronylation and Silaboration of Unsaturated Compounds; 1.3.4.7 Other Methods; 1.3.5 Alkynylboronic Acids; 1.3.6 Alkylboronic Acids; 1.3.7 Allylic Boronic Acids; 1.3.8 Chemoselective Transformations of Compounds Containing a Boronic Acid (Ester) Substituent; 1.3.8.1 Oxidative Methods; 1.3.8.2 Reductive Methods; 1.3.8.3 Generation and Reactions of a-Boronyl-Substituted Carbanions and Radicals; 1.3.8.4 Reactions of a-Haloalkylboronic Esters; 1.3.8.5 Other Transformations; 1.3.8.6 Protection of Boronic Acids for Orthogonal Transformations

1.4 Isolation and Characterization1.4.1 Recrystallization and Chromatography; 1.4.2 Solid Supports for Boronic Acid Immobilization and Purification; 1.4.2.1 Diethanolaminomethyl Polystyrene; 1.4.2.2 Other Solid-Supported Diol Resins; 1.4.3 Analytical and Spectroscopic Methods for Boronic Acid Derivatives; 1.4.3.1 Melting Points, Combustion Analysis, and HPLC; 1.4.3.2 Mass Spectrometry; 1.4.3.3 Nuclear Magnetic Resonance Spectroscopy; 1.4.3.4 Other Spectroscopic Methods; 1.5 Overview of the Reactions of Boronic Acid Derivatives; 1.5.1 Metalation and Metal-Catalyzed Protodeboronation

1.5.2 Oxidative Replacement of Boron

Sommario/riassunto

Following the huge success of the first edition, which has become THE reference source for everyone working in the field, this long-awaited, completely updated edition features almost 50% new content.The world-renowned chemist Prof Dennis Hall is joined by a select group of top authors to cover all modern aspects of boronic acid derivatives in one comprehensive handbook. The experimental procedures described make for extremely useful reading. From the reviews of the first edition: ""...deserves to be on the bookshelf of all synthetic chemists, whether in discovery or process chemistry.