1.

Record Nr.

UNINA9910554822903321

Titolo

Advances in metallodrugs : preparation and applications in medicinal chemistry / / edited by Shahid-ul-Islam, Athar Adil Hashmi, Salman Ahmad Khan

Pubbl/distr/stampa

Hoboken, NJ : , : Wiley, , ℗2020

ISBN

1-119-64100-4

1-119-64101-2

1-119-64086-5

Descrizione fisica

1 online resource (427 pages)

Collana

Emerging trends in medicinal and pharmaceutical chemistry

Disciplina

615.19

Soggetti

Metals - Therapeutic use

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

Includes index.

Sommario/riassunto

"Over the past few decades, medicinal inorganic chemistry as an interdisciplinary sub-area of bioinorganic chemistry has received the growing attention of researchers in the search for promising antimicrobial, antimalarial, antiviral, and antitumor chemotherapeutic agents. An excellent compilation of reports on metal complexes has revealed the potency of metal complexes as better therapeutic agents. Metal-containing drugs have several promising advantages over organic ligands and have gained the trust of researches after the worldwide approval of the drug cisplatin. Their distinct mechanism of action makes them perfect candidates as alternatives to the conventional drugs to which resistance has already been shown. In this direction, a huge number of transition metal complexes have been synthesized and evaluated for their biological profiles"--