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Record Nr. |
UNINA9910553076503321 |
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Titolo |
Xenopus : from basic biology to disease models in the genomic era / / edited by Abraham Fainsod, Sally A. Moody |
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Pubbl/distr/stampa |
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Boca Raton : , : Taylor & Francis, , 2022 |
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©2022 |
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Descrizione fisica |
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1 online resource (360 pages) |
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Disciplina |
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Soggetti |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Section I. -- 1. A quick history of Xenopus. -- 2. The study of cell division controla and DNA replication in Xenopus egg extracts. -- 3. Maternal gene control of embryogenesis: germ cell determination and germ layer formation. -- 4. Signaling components in dorsal-ventral patterning and the Organizer. -- 5. Signaling pathways in anterior-posterior patterning. -- 6. Wnt signaling in tissue differentiation and morphogenesis. -- 7. Multiple functions of Notch signaling during early embryogenesis. -- 8. The development and evolution of the vertebrate neural crest: Insights from Xenopus. -- 9. The use of Xenopus oocytes to study the biophysics and pharmacological properties of receptors and channels. -- Section II. -- 10. The continuing evolution of the Xenopus genome. -- 11. Dynamics of chromatin remodeling during Xenopus development. -- 12. Gene regulatory networks controlling Xenopus embryogenesis. -- 13. The development of high-resolution proteomic analyses in Xenopus. -- 14. Advances in genome editing tools. -- Section III. -- 15. Formation of the left-right axis: insights from the Xenopus model. -- 16. Discovering the function of congenital heart disease genes. -- 17. Craniofacial development and disorders - contributions of Xenopus. -- 18. Modeling digestive and respiratory system development and disease in Xenopus. -- 19. Functional neurobiology and insights into human disease. -- 20. Leaping towards the understanding of spinal cord regeneration. -- 21. Studying tumor formation and regulation in Xenopus. -- 22. Xenopus: a model to study |
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