| |
|
|
|
|
|
|
|
|
1. |
Record Nr. |
UNINA9910465038903321 |
|
|
Titolo |
Next-generation sequencing : current technologies and applicaitons / / edited by Jianping Xu |
|
|
|
|
|
|
|
Pubbl/distr/stampa |
|
|
Norfolk, England : , : Caister Academic Press, , [2014] |
|
©2014 |
|
|
|
|
|
|
|
|
|
ISBN |
|
|
|
|
|
|
Descrizione fisica |
|
1 online resource (173 p.) |
|
|
|
|
|
|
Disciplina |
|
|
|
|
|
|
Soggetti |
|
Bioinformatics |
Nucleotide sequence |
Sequence alignment (Bioinformatics) |
Sequential analysis |
Electronic books. |
|
|
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Note generali |
|
Description based upon print version of record. |
|
|
|
|
|
|
Nota di bibliografia |
|
Includes bibliographical references and index. |
|
|
|
|
|
|
Nota di contenuto |
|
Contents; Current books of interest; Contributors; Preface; 1; An Overview of Next-generation Genome Sequencing Platforms; Introduction; Second generation sequencing platforms; Third-generation sequencing platforms; Concluding remarks; 2: Attomole-level Genomics with Single-molecule Direct DNA, cDNA and RNA Sequencing Technologies; Introduction; Materials; Methods; 3: SNP Assessment on Draft Genomes from Next-generation Sequencing Data; Background; Single nucleotide polymorphisms (SNPs); SNP calling with one sample on draft genomes with ACCUSA |
Head-to-head comparisons of sequenced samples with ACCUSA 2Conclusions; 4: Processing Large-scale Small RNA Datasets in Silico; Introduction; Library preparation and sequencing; Helper tools; Analysis tools; Visualization tools; Discussion; 5: Utility of High-throughput Sequence Data in Rare Variant Detection; What is a rare variant?; Why is variant detection needed?; Utility of non-HTS methods for minority and rare variant detection; Status of rare variant detection by analysis of HTS data; How much HTS data is needed to accurately detect rare variants? |
|
|
|
|
|
|
|
|
|
|
|
Testing the feasibility of analysing HTS for rare SNP detectionSources of errors; Experimental validation of correction approaches; Conclusions; 6: Detecting Breakpoints of Insertions and Deletions from Paired-end Short Reads; Introduction; Pindel: a pattern growth method to identify precise breakpoints of indels and SVs; Performance on real data (NA18507); Recent developments; Further advances of split-read approaches; Conclusion and future perspectives; 7: Novel Insights from Re-sequencing of Human Exomes Through NGS; Introduction; The protocol; Exome capture platforms and kits |
Quality control and performance evaluationBioinformatics analysis; Applications in human disease research; Perspective; 8: Insights on Plant Development Using NGS Technologies; Introduction; Use RNA-seq to dissect transcription at the cellular resolution; Use ChIP-seq to dissect transcriptional networks; Use ChIP-seq to analyse the epigenome; Conclusions and perspectives; 9: Next-generation Sequencing and the Future of Microbial Metagenomics; Introduction; Tracking microbial diversity; Applying omics technologies; Designing experiments; Modelling microbial diversity; Concluding remarks |
10: Next-generation Sequencing, Metagenomes and the Human MicrobiomeIntroduction; Marker-specific microbial community surveys; Metagenomics - high-throughput shotgun (HTS sequencing) of microbial communities; Applications of metagenomics to the study of human health and disease; Beyond the omes - systems biology views onto the host-microbiome interactions; The new generation of cloud-based informatics solutions for next-generation sequencing; Conclusion; Index |
|
|
|
|
|
|
Sommario/riassunto |
|
High-throughput, next generation sequencing (NGS) technologies are capable of producing a huge amount of sequence data in a relatively short time and have revolutionized genome research in recent years. The powerful and flexible nature of NGS has made it an indispensable tool for a broad spectrum of biological sciences, and NGS technologies have transformed scientific research in many fields. Written by experts from around the world, this book explores the most recent advances in NGS instrumentation and data analysis. The book begins with a comprehensive description of current NGS platforms, t |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
2. |
Record Nr. |
UNINA9910502599603321 |
|
|
Autore |
Allain Thierry |
|
|
Titolo |
Entre deux rives : Villes en Méditerranée au Moyen Âge et à l’époque moderne / / Gilbert Buti, Élisabeth Malamut, Mohamed Ouerfelli, Paolo Odorico |
|
|
|
|
|
|
|
Pubbl/distr/stampa |
|
|
Aix-en-Provence, : Presses universitaires de Provence, 2021 |
|
|
|
|
|
|
|
ISBN |
|
|
|
|
|
|
Descrizione fisica |
|
1 online resource (536 p.) |
|
|
|
|
|
|
Collana |
|
|
|
|
|
|
Altri autori (Persone) |
|
AmaraAllaoua |
BlancFabien |
BramoulléDavid |
CagnanaAurora |
CalcagnoPaolo |
CanepariEleonora |
CarytsiotisMarie-Myriam |
ChalletVincent |
ConesaMarc |
DelzantJean-Baptiste |
DurandStéphane |
EychenneMathieu |
LimousinÉric |
MagdalinoPaul |
MagnaniMatteo |
MalamutÉlisabeth |
MenjotDenis |
MeouakMohamed |
Michienzi IngridHoussaye |
Otchakovsky-LaurensFrançois |
OuerfelliMohamed |
PécoutThierry |
TaharAbdelkader |
Touarigt BelkhodjaAssia |
TraversoAntonella |
TrélatPhilippe |
TroadecCécile |
ButiGilbert |
OdoricoPaolo |
|
|
|
|
|
|
|
|
Soggetti |
|
Cities and towns - Mediterranean Region - History |
|
|
|
|
|
|
|
|
|
|
Cities and towns, Medieval |
Sociology, Urban - Mediterranean Region - History |
Mediterranean Region History 1517-1789 Congresses |
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Sommario/riassunto |
|
"La Méditerranée des villes est déclinée dans une perspective braudélienne et une approche sociologique. Villes comme noeuds de communication de routes mariteles, depuis les villes portuaires du Nil et l'île-cité de Patmos jusqu'aux brillantes capitales, Constantinople ou Damas, ou de moins illustres comme Savone ou Smyrne qui eurent pourtant leur heure de gloire. D'autres villes, comme Tlemcen et Bône, se caractérisent par une sédimentation mémorielle, depuis l'Antiquité en passant par la medina médiévale jusqu'à l'époque coloniale qui bouleversa leur configuration. Avec les villes de la Méditerranée sont appréhendés leur histoire spécifique, l'ancrage du pouvoir et l'extension de leur territoire. Telle la ville-port de Gênes marquée par des emprises successives sur l'espace, mais aussi Grasse avec ses tours ou encore les villes d'Italie centrale avec le palais des seigneurs et les domus familiales. Marseille se situe dans la confrontation entre la commune et l'autorité royale: elle se veut autonome, parfois indépendante et insoumise. Rome passe d'une capitale à éclipse à une grande capitale où la centralisation, la renovatio urbis et les migrations transforment la société et le visage des quartiers périphériques. Apparaissent alors les communautés urbaines, leur vivre ensemble et leur identité. C'est l'histoire en devenir des communautés religieuses de Ciutat de Majorque. C'est le regard des nomades du Maghreb sur les villes. Ce sont les espaces de sociabilité dans les villes chypriotes. Enfin, la communauté politique peut s'écrire et perdurer, comme la Chronique de Montpellier, jusqu'à ce que guerres de religion et guerre civile brisent ce qui en faisait le ciment et la mémoire."--Page [4] of cover. |
|
|
|
|
|
|
|
| |