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1. |
Record Nr. |
UNINA990001156210403321 |
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Autore |
Yap, H.P. |
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Titolo |
Some Topics in Graph Theory / by Yap H.P. |
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Pubbl/distr/stampa |
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Cambridge [etc.] : Cambridge University Press, 1986 |
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Collana |
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London Mathematical Society lecture note series ; 108 |
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Collocazione |
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Materiale a stampa |
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Livello bibliografico |
Monografia |
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2. |
Record Nr. |
UNINA9910495897903321 |
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Autore |
Aguilera Peña Mario |
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Titolo |
Violencia y estrategias colectivas en la región andina : Bolivia, Colombia, Ecuador, Perú y Venezuela |
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Pubbl/distr/stampa |
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Bogotá, : Institut français d’études andines, 2015 |
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ISBN |
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Descrizione fisica |
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1 online resource (656 p.) |
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Altri autori (Persone) |
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AlbóXavier |
BarrigMaruja |
Cajías de la VegaMagdalena |
Cubides CFernando |
DaviaudSophie |
DegregoriCarlos Iván |
Ferro MedinaJuan Guillermo |
GuerreroAndrés |
Hernández ArveloMiguel Ángel |
LairEric |
MeertensDonny |
PécautDaniel |
RomeroMauricio |
Sánchez GómezGonzalo |
TheidonKimberly |
Vargas MezaRicardo |
SánchezGonzalo |
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Soggetti |
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Political violence - Andes Region |
Violence - Andes Region |
Guerrillas - Andes Region |
Insurgency - Andes Region |
Drug traffic - Andes Region |
Andes Region Politics and government |
Andes Region Social conditions |
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Materiale a stampa |
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Livello bibliografico |
Monografia |
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Sommario/riassunto |
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El área andina parece hundida en la incertidumbre: ni gobiernos democráticos, ni ensayos populistas y mucho menos proyectos autoritarios han logrado darle una perspectiva de estabilidad económica, institucional y política a la región. Muy por el contrario, afloran en ella persistentes formas de exclusión, exacerbadas por un proceso de globalización a ultranza, e inevitables expresiones de inconformidad y de violencia, de las cuales Colombia es sólo el caso extremo, en cuyo espejo se miran los demás. El propósito de este libro no es otro que el de proveer, a partir de distintos enfoques interdisciplinarios y de autores con reconocida trayectoria, en sus respectivos campos y países, nuevos elementos empíricos, nuevos enfoques analíticos y nuevas categorías que nos permitan (re)pensar algunos de los puntos nodales de la violencia colectiva en la zona andina. Para ello, el libro está organizado en torno a cinco ejes temáticos que se relacionan entre sí: dinámicas y representaciones del conflicto armado; drogas, grupos armados y privatización de la violencia; formas de acción colectiva en las comunidades indígenas; la relación justicia-violencia y la acción colectiva; y, finalmente, los roles adquiridos por las mujeres en los diferentes entornos sociopolíticos. |
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3. |
Record Nr. |
UNINA9910800113003321 |
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Autore |
Pörtner Ralf |
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Titolo |
Biopharmaceutical Manufacturing : Progress, Trends and Challenges / / edited by Ralf Pörtner |
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Pubbl/distr/stampa |
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Cham : , : Springer International Publishing : , : Imprint : Springer, , 2023 |
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ISBN |
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Edizione |
[1st ed. 2023.] |
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Descrizione fisica |
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1 online resource (497 pages) |
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Collana |
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Cell Engineering, , 2542-9515 ; ; 11 |
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Disciplina |
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Soggetti |
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Cytology |
Biomedical engineering |
Biotechnology |
Biochemical engineering |
Pharmaceutical chemistry |
Vaccines - Biotechnology |
Biomaterials |
Cell Biology |
Biomedical Engineering and Bioengineering |
Bioprocess Engineering |
Pharmaceutics |
Biomaterials-Vaccines |
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Materiale a stampa |
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Livello bibliografico |
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Nota di contenuto |
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Part I: Manufacturing of Recombinant Therapeutic Proteins -- Chapter 1. Single-Use Systems in Biopharmaceutical Manufacture: State of the Art and Recent Trends (Jossen et al.) -- Chapter 2. Recent Developments in Bioprocess Monitoring Systems (Rahmatnejad et al.) -- Chapter 3. Advances in Characterization of Industrial Bioreactors for Cell Culture Process (Fitschen et al.) -- Chapter 4. Continuous Bioprocessing for Upstream Process - Perfusion Process (Chotteau et al.) -- Chapter 5. Continuous Bioprocessing for Downstream (Gerstweiler) -- Chapter 6. Towards Digital Twin for Biopharmaceutical |
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Processes: Concept and Progress (Ding et al.) -- Chapter 7. Integrated Process and Supply Chain Design and Optimization (Triantafyllou et al.) -- Chapter 8. Production of Complex Proteins in Plants – From Farming to Manufacturing (Nausch et al.) -- Chapter 9. Manufacturing of Recombinant Proteins Using Quality by Design (QbD) Methodology: Current Trend and Challenges (Shin and Landauer) -- Chapter 10. Biopharma 4.0 for Biologics Manufacturing Under Pandemic Constraints (Schmidt et al.) -- Chapter 11. Biopharma 4.0: Digital Technologies Driving Smart Manufacturing (Nargund et al.) -- Part II: Manufacturing Aspects of Cell and Gene Therapy -- Chapter 12. Essential Aspects of Mesenchymal Stem Cell Manufacturing (Fleischhammer et al.) -- Chapter 13. Towards a Continuous Production of Human Mesenchymal Stromal Cells in a Chemically Defined Medium: Opportunities and Challenges for a Robust and Scalable Expansion Process (Tasto and Salzig) -- Chapter 14. Biomanufacturing Aspects of Gene Therapy (Warnock) -- Chapter 15. Manufacturing and Quality of Advanced Therapeutics: Cellular Therapies, CAR-T and Gene Therapies (van den Bos et al.). |
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Sommario/riassunto |
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This volume “Cell Engineerring 11 - Biopharmaceutical Manufacturing: Progress, Trends and Challenges” is a source of the latest innovative research and technical development in biomanufacturing systems. It is organised into 2 parts: 1) Manufacturing of recombinant therapeutic proteins (e.g. therapeutic antibodies, biosimilars/biogenerics) and 2) Manufacturing aspects of cell and gene therapy. Each with selected chapters on the following topics for both up- and downstream, such as: Advanced process strategies, especially continuous manufacturing, Advanced culture techniques, especially single-use systems, Process transfer, scale-up/scale-down models, Processing advances/Manufacturing productivity/efficiency, Model-assisted process understanding and development/Digital Twins, Process controls and analytics, Quality control, Quality by design, Facility design and full-scale commercial systems, manufacturing technology innovation. The book comprises contributions of experts from academia and industry active in the field of cell culture development for the production of recombinant proteins, cell therapy and gene therapy, with consideration of Digital Twin´s and facility design. The knowledge and expertise of the authors cover disciplines like cell biology, engineering, biotechnology and biomedical sciences. Inevitably, some omissions will occur in the test, but the authors have sought to avoid duplications by extensive cross-referencing to chapters in other volumes of this series and elsewhere. We hope the volume provides a useful compendium of techniques for scientists in industrial and research laboratories active in this field. |
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