1.

Record Nr.

UNINA9910491028203321

Titolo

Atlas of clinical PET-CT in treatment response evaluation in oncology / / Stefano Fanti, Gopinath Gnanasegaran, Ignasi Carrió, editors

Pubbl/distr/stampa

Cham, Switzerland : , : Springer, , [2021]

©2021

ISBN

3-030-68858-5

Descrizione fisica

1 online resource (483 pages)

Disciplina

616.99407575

Soggetti

Cancer - Tomography

Quimioteràpia del càncer

Radioteràpia

Tomografia per emissió de positrons

Llibres electrònics

Atles (Científic)

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Intro -- Contents -- List of Contributors -- Part I: Therapy Response Evaluation: Science and Practice -- 1: Treatment Response Evaluation: Science and Practice -- 1.1  Introduction -- 1.2  Criteria for Evaluating Response -- 1.3  Traditional Response Criteria -- 1.4  Incorporation of Molecular Imaging into Response Criteria -- 1.5  Response Criteria and Immunotherapy -- 1.6  Practical Considerations -- References -- 2: CT in Treatment Response Assessment in Oncology -- 2.1  Introduction -- 2.2  Current Response Assessment Criteria for Chemotherapy and Targeted Therapies -- 2.3  Pitfalls of RECIST 1.1 -- 2.4  mRECIST in HCC -- 2.5  Lugano Classification in Lymphoma -- 2.6  Response Assessment Criteria in Immunotherapy -- 2.7  Conclusion -- References -- 3: MRI and Diffusion-Weighted MRI in Treatment Response Evaluation Overview -- 3.1  Introduction -- 3.2  Response Evaluation by Tumour Burden or Anatomical Parameters -- 3.2.1  WHO and RECIST Criteria -- 3.2.2  iRECIST -- 3.2.3  Other Response Evaluation by Anatomical MRI in Specific Disease Contexts -- 3.2.3.1  Brain Tumour -- 3.2.3.2  Hepatocellular Carcinoma (HCC) --



3.2.3.3  Rectal Cancer -- 3.3  Response Evaluation with Diffusion-Weighted Imaging (DWI) -- 3.4  Conclusion -- References -- 4: PET and PET-CT in Treatment Response Evaluation: Overview -- 4.1  Introduction: Why Is Tumor Response Assessed by Imaging? -- 4.2  Assessment of Tumor Response: When and How? -- 4.2.1  Response Assessment by FDG PET -- 4.2.1.1  Response Assessment in Lymphoma -- 4.2.2  Response Assessment with Other PET Imaging Agents -- 4.2.3  Timing of Response Assessment -- 4.3  Responders vs. Nonresponders -- 4.4  Management and Type of Treatment -- 4.5  Common Patterns, Pitfalls, Variants, Advantages, and Limitations -- 4.5.1  Standardized Imaging Protocol -- 4.5.2  Impact of Therapy on FDG Metabolism.

4.5.3  Radiation Therapy -- 4.5.4  Immunotherapy -- 4.5.5  Clinical Image Interpretation -- References -- 5: Conventional Radiological Techniques and PET-CT in Treatment Response Evaluation in Postsurgical Setting -- 5.1  Introduction -- 5.2  Computed Tomography (CT) -- 5.3  Magnetic Resonance Imaging (MRI) -- 5.4  Positron Emission Tomography (PET) -- 5.5  Other Radiotracers (Neuroendocrine Tumors, Prostate Cancer) -- 5.6  Conclusion -- References -- 6: Conventional Radiological and PET-CT Assessment of Treatment Response Evaluation in Chemotherapy Setting -- 6.1  Introduction -- 6.2  Conventional Radiological Techniques -- 6.3  PET/CT in Response Assessment to Chemotherapy -- 6.3.1  EORTC -- 6.3.2  IHP Criteria for Lymphoma -- 6.3.3  Deauville Criteria for Lymphoma -- 6.3.4  PERCIST -- 6.4  MRI and CT in Response Assessment to Chemotherapy -- 6.5  Evaluation of Response to Chemotherapy in Individual Tumours -- 6.5.1  Oesophageal and Gastric Cancer -- 6.5.2  Colorectal Cancer -- 6.5.3  Hepatocellular Carcinoma -- 6.5.4  Pancreatic Cancer -- 6.5.5  Lung Cancer -- 6.5.6  Lymphoma -- 6.5.7  Head and Neck Cancer -- 6.5.8  Breast Cancer -- 6.5.9  Other Tumours -- 6.6  Conclusion -- References -- 7: Conventional Radiological Techniques and PET-CT in Treatment Response Evaluation in Post-Radiotherapy Setting -- 7.1  Introduction -- 7.2  Functional Imaging for Disease Response Assessment to Radiotherapy -- 7.2.1  Functional, Metabolic PET Imaging -- 7.2.1.1  Glucose Metabolism -- 7.2.1.2  Tumor Hypoxia -- 7.2.1.3  Tumor Cell Proliferation -- 7.2.1.4  Apoptosis -- 7.2.1.5  Amino Acid Transport and Protein Synthesis -- 7.2.1.6  Cell Membrane Synthesis -- 7.2.1.7  Epidermal Growth Factor Receptor Status -- 7.2.2  Functional MR Imaging Techniques -- 7.2.2.1  Dynamic Contrast-Enhanced MR Imaging -- 7.2.2.2  Diffusion-Weighted MR Imaging -- 7.2.2.3  BOLD Imaging.

7.2.2.4  MR Spectroscopy -- 7.2.3  Functional Imaging with Perfusion CT -- 7.2.4  Emerging Integrated Hybrid Imaging Techniques -- 7.2.4.1  Integrated PET/CT Perfusion Imaging -- 7.2.4.2  Integrated PET-MR Imaging -- 7.3  Assessment of Treatment Response After Radiotherapy -- 7.3.1  Anatomic Response Criteria (WHO, RECIST) -- 7.3.1.1  WHO Criteria -- 7.3.1.2  RECIST v1.1 -- 7.3.1.3  Limitations of Anatomic Response Criteria -- 7.3.2  Metabolic Response Criteria -- 7.3.2.1  Qualitative Assessment -- 7.3.2.2  Quantitative Assessment (PERCIST v1.0) -- 7.4  Current Uses of FDG PET/CT in Treatment Response Following Radiation Therapy -- 7.4.1  Head and Neck Cancer -- 7.4.2  Esophageal Carcinoma -- 7.4.3  Rectal Carcinoma -- 7.4.4  Brain Tumors -- 7.4.5  Cervical Carcinoma -- 7.4.6  Lung Carcinoma -- 7.4.7  Hepato-Pancreatico-Biliary Tumors, Particularly Pancreatic Carcinoma and Liver Metastases (Postselective Internal Radiotherapy Treatment) -- References -- 8: Conventional Radiological Techniques and PET-CT in Treatment Response Evaluation in Immunotherapy



Settings -- 8.1  Introduction -- 8.2  Management: Type of Treatments/Regimes -- 8.2.1  Melanoma -- 8.2.2  NSCLC -- 8.2.3  Other Solid Tumors -- 8.3  Pathophysiology -- 8.4  Assessment of Treatment Response -- 8.4.1  Anatomic Response Assessment -- 8.4.2  Metabolic Response Criteria -- 8.4.3  Responders Vs. Non-Responders -- 8.4.4  Pitfalls and beyond (Pseudo-, Hyper-Progression, irAEs, Brain Mets, Cost-Effectiveness) -- References -- 9: Treatment Response Evaluation of Bone Metastases Using 18F-NaF -- 9.1  Introduction -- 9.2  Management and Types of Treatments -- 9.2.1  Baseline 18F-Fluoride PET/CT -- 9.2.1.1  Prostate Cancer -- 9.2.1.2  Breast Cancer -- 9.2.1.3  Lung Cancer -- 9.2.1.4  Thyroid Cancer -- 9.2.1.5  Renal Cell Cancer.

9.3  Assessment of Treatment Response (Postsurgical, Post Chemotherapy, Post Radiotherapy, Neoadjuvant, and Immunotherapy Settings) -- 9.3.1  Interim 18F-Fluoride PET/CT -- 9.3.1.1  Prostate Cancer -- 9.3.1.2  Breast Cancer -- 9.3.2  Follow-Up 18F-Fluoride PET/CT -- 9.3.2.1  Prostate Cancer -- 9.3.2.2  Breast Cancer -- 9.3.2.3  Multiple Myeloma -- 9.3.2.4  Metastatic Primary Bone Tumors -- 9.3.3  Conclusions -- 9.4  Common Patterns, Pitfalls, Variants, Advantages, and Limitations -- References -- 10: Reporting Post-Therapy Scans -- 10.1  Introduction -- 10.2  Patient Preparation -- 10.3  Clinical Details -- 10.4  Questions to Ask Patient -- 10.5  When to Scan -- 10.6  What to Look for in the Scans -- 10.7  How to Describe, Report Post-Therapy Finding Scores, Criteria, etc. (Post-Surgical, Post-Chemotherapy, Post-Radiotherapy, and Post-Immunotherapy Settings) -- 10.8  Common and Less Common Findings -- 10.9  How to Interpret the Findings: Dos and Don'ts -- 10.9.1  What to Do -- 10.9.2  What Not to Do -- 10.10  What to Advise the Referrers -- References -- Part II: Therapy Response Evaluation: Clinical Atlas -- 11: 18F-FDG PET/CT in Treatment Response Evaluation in Head and Neck Cancer -- 11.1  Case 1 -- 11.2  Case 2 -- 11.3  Case 3 -- 11.4  Case 4 -- 11.5  Case 5 -- 11.6  Case 6 -- 11.7  Case 7 -- 11.8  Case 8 -- 11.9  Case 9 -- 11.10  Case 10 -- 11.11  Case 11 -- 11.12  Case 12 -- 11.13  Case 13 -- 11.14  Case 14 -- 11.15  Case 15 -- Suggested Reading -- Case 3 -- 12: PET/CT in Treatment Response Evaluation: Lung Cancer -- 12.1  Introduction -- References -- 13: 18F-FDG PET/CT and Non 18F-FDG-PET/CT in Treatment Response Evaluation in Neuro-Oncology -- 13.1  Introduction -- 13.2  PET Tracers Used in Neuro-Oncology -- 13.3  Case 1 -- 13.4  Case 2 -- 13.5  Case 3 -- 13.6  Case 4 -- 13.7  Case 5 -- 13.8  Case 6 -- 13.9  Case 7 -- 13.10  Case 8.

13.11  Case 9 -- 13.12  Case 10 -- 13.13  Case 11 -- 13.14  Case 12 -- 13.15  Case 13 -- 13.16  Case 14 -- 13.17  Case 15 -- References -- 14: PET/CT in the Assessment of Treatment Response in Hepatobiliary, Gall Bladder and Pancreatic Malignancies -- 14.1  Introduction -- 14.2  Case 1 -- 14.3  Case 2 -- 14.4  Case 3 -- 14.5  Case 4 -- 14.6  Case 5 -- 14.7  Case 6 -- 14.8  Case 7 -- 14.9  Case 8 -- 14.10  Case 9 -- 14.11  Case 10 -- 14.12  Case 11 -- 14.13  Case 12 -- 14.14  Case 13 -- 14.15  Case 14 -- 14.16  Case 15 -- 14.17  Case 16 -- 14.18  Case 17 -- 14.19  Case 18 -- Suggested Reading -- Introduction -- Case 1 -- Case 2 -- Case 3 -- Case 4 -- Case 6 -- Case 7 -- Case 8 -- Case 11 -- 15: 18F-FDG PET/CT in Treatment Response Evaluation: Gastroesophageal Cancer -- 15.1  Introduction -- 15.2  Case No. 1: Radiation-Induced Esophagitis -- 15.3  Case No. 2: Radiation-Induced Pneumonitis -- 15.4  Case No. 3: Post Transthoracic Esophagectomy (TTE) Appearance -- 15.5  Case No. 4: Aspiration Pneumonia -- 15.6  Case No. 5: Recurrent Aspiration Pneumonia -- 15.7  Case No. 6: Tracheoesophageal Fistula (TOF) -- 15.8  Case No. 7: Upper Esophageal Mass with Complete Response Post CTRT -- 15.9  



Case No. 8: Post CTRT Complete Response with Inflammatory Changes in the Esophagus -- 15.10  Case No. 9: Complete Response on PET/CT with Microscopic Residual Disease on Histopathology -- 15.11  Case No. 10: Posttreatment Changes Vs. Residual Disease -- 15.12  Case No. 11: Partial Response to Treatment -- 15.13  Case No. 12: Stable Disease with Radiation-Induced Esophagitis -- 15.14  Case No. 13: GE Junction Mass with Partial Response -- 15.15  Case No. 14: Complete Response -- 15.16  Case No. 15: Coexisting Malignancy and Granulomatous Infection -- 15.17  Case No. 16: Esophageal Primary with Coexisting Tuberculous Infection in the Lungs.

15.18  Case No. 17: GE Junction and Proximal Stomach Mass with Partial Response.