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Record Nr. |
UNINA9910488694203321 |
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Autore |
Singer Michael C. |
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Titolo |
Innovations in modern endocrine surgery / / Michael C. Singer, David J. Terris |
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Pubbl/distr/stampa |
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Cham, Switzerland : , : Springer, , [2021] |
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©2021 |
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ISBN |
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Descrizione fisica |
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1 online resource (292 pages) |
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Disciplina |
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Soggetti |
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Endocrine glands - Surgery |
Cirurgia endocrina |
Llibres electrònics |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Intro -- Preface -- Contents -- Contributors -- Part I: Diagnosis and Preoperative Work-up of Thyroid Disease -- Chapter 1: Ultrasound for Thyroid Nodule Risk Stratification -- Introduction -- Ultrasound Setting and Image Acquisition -- Gray-scale Ultrasound Characteristics of Thyroid Nodules -- Doppler Flow in Thyroid Nodule Evaluation -- Elastography -- Risk Stratification System -- Conclusion -- References -- Chapter 2: Molecular Assessment of Thyroid Nodules -- Introduction -- Cytological Nomenclature of Thyroid Nodules -- Current Trends in the Management of Indeterminate Nodules and Guideline Recommendations -- Machinery of Genomics to Phenotype: DNA, mRNA, ncRNA, and Protein -- Genomics of Thyroid Cancer -- Papillary Thyroid Cancer -- Follicular Adenoma and Follicular Thyroid Cancer -- Hürthle Cell Cancer -- Medullary Thyroid Cancer -- Genomics in Cytologically Indeterminate Results -- Commercially Available Thyroid Nodule Molecular Tests -- Afirma® Gene Expression Classifier and Afirma Gene Sequencing Classifier -- ThyroSeq -- ThyGeNEXT+ThyraMIR -- How to Use Molecular Testing Results to Guide Surgery -- Molecular Diagnostics Beyond Bethesda III/IV Nodules -- Future Directions -- Guiding Initial Management and Subsequent Follow-Up Strategies in Malignant Cases -- Prognostics of Benign Nodules -- Summary -- References -- Chapter |
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3: Active Surveillance for Thyroid Cancer -- Introduction -- Incidence of Thyroid Cancer -- Cost of Thyroid Cancer Care -- Complications of Thyroid Surgery -- Reducing Thyroid Cancer Diagnosis -- Active Surveillance -- Clinical Data -- Adoption/Implementation of Active Surveillance -- Cost-Effectiveness -- Future Directions -- Conclusions -- References -- Chapter 4: Hemithyroidectomy for Differentiated Thyroid Cancer -- Historical Context and Overview -- Oncologic Outcomes Following Hemithyroidectomy. |
Clinical Framework to Guide Decision-Making Processes Regarding the Extent of Initial Surgery for Differentiated Thyroid Cancer -- Step 1: Preoperative Evaluation -- Step 2: Intra-operative Evaluation -- Step 3: Postoperative Evaluation -- Follow-Up Recommendations Following Hemithyroidectomy -- Conclusions -- References -- Chapter 5: Neoadjuvant Therapy for Anaplastic Thyroid Carcinoma -- Introduction -- Clinical Presentation, Histopathology, and Staging of Advanced ATC -- Molecular Pathogenesis -- Neoadjuvant Therapy -- External Beam Radiation -- Cytotoxic Chemotherapy -- BRAF-Directed Therapy -- Conclusion -- References -- Chapter 6: Nonoperative Thyroid Ablation Techniques for Benign Thyroid Nodules -- Introduction -- HIFU Ablation -- Nodule Selection -- Before Ablation -- Evidence Supporting the Role of HIFU -- Clinical Application -- Efficacy of HIFU Ablation -- Safety of HIFU Ablation -- Radiofrequency Ablation (RFA) -- Nodule Selection -- Preoperative Evaluation and Preparation -- RFA -- Moving Shot Technique -- Efficacy of RFA Ablation -- Safety of RFA -- Discussion -- Conclusion -- References -- Part II: Diagnosis and Preoperative Work-up of Parathyroid Disease -- Chapter 7: Localization Studies for Hyperparathyroidism -- Introduction -- Historical Perspectives on Parathyroid Localization -- The Role of Imaging in Parathyroid Surgery -- Anatomical Imaging Modalities -- Ultrasonography -- Description of Technology and Technique -- Four-Dimensional Computed Tomography -- Magnetic Resonance Imaging -- Functional Imaging Modalities -- Nuclear Scintigraphy -- SPECT/SPECT-CT -- PET/CT -- Invasive Techniques -- Fine-Needle Aspiration Biopsy -- Selective Venous Sampling and Selective Arteriography -- Choice of Imaging Modalities -- Conclusion -- References -- Chapter 8: Subtle Variants of Hyperparathyroidism: Normohormonal Hyperparathyroidism. |
Introduction -- Incidence and Etiology -- Presentation -- Biochemical Profile and Interpretation -- Localization Studies -- Intraoperative Findings and Decision-Making -- Long-Term Success and Outcomes -- Conclusions and Future Investigation -- References -- Chapter 9: Subtle Variants of Hyperparathyroidism: Normocalcemic Hyperparathyroidism -- Introduction -- Pathophysiology -- Diagnostic Criteria -- Epidemiology -- Clinical Features and Course of Disease -- Nonspecific Symptoms -- Natural History of NCHPT -- Management of NCHPT -- Surgical Management of NCHPT -- Outcomes After Parathyroidectomy -- Conclusion -- References -- Chapter 10: Indications for Parathyroidectomy -- Parathyroid-Related Hypercalcemia -- Effects of PTH-Mediated Hypercalcemia -- When to Intervene -- Indications for Surgery -- References -- Part III: Surgical Adjuncts -- Chapter 11: Intermittent Neuromonitoring of the Recurrent Laryngeal Nerve -- Introduction -- Background -- Challenges in IONM Adoption -- IONM Application in Present-Day Clinical Practice -- Application of Intraoperative Nerve Monitoring -- Negative Predictive Value (NPV) -- Positive Predictive Value (PPV) -- Technique -- Equipment -- Anesthesia Considerations -- IONM Data Gathering -- Electromyography (EMG) Waveform: Amplitude, Latency, and Threshold -- Loss of Signal -- Establishing an Adequate Baseline -- Evaluation |
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of Equipment Malfunction -- True Loss of Signal -- Troubleshooting a LOS -- False Negative vs. False Positive Results -- Management Strategies -- Staged Surgery -- Recent Advances in IONM and Future Directions -- Continuous Vagal Monitoring -- Superior Laryngeal Nerve (SLN) Monitoring -- Intraoperative Identification of Nonrecurrent Laryngeal Nerve -- Conclusion -- References -- Chapter 12: Continuous Neuromonitoring of the Recurrent Laryngeal Nerve -- Introduction -- Rationale for Use of c-IONM. |
Standardized Approach to c-IONM -- Interpretation of c-IONM EMG Data -- Impending Neural Injury -- Artifact -- Signal Recovery -- False Positive and False Negative Events -- Staged Thyroidectomy with c-IONM -- Safety of c-IONM -- c-IONM vs. i-IONM -- Future Perspectives -- References -- Chapter 13: Neuromonitoring of the Superior Laryngeal Nerve -- Introduction -- Injury to the EBSLN and Its Consequences -- Fundamentals of EBSLN Preservation: How It Was Done Prior to IONM -- IONM and EBSLN Preservation -- Benefits of IONM -- Conclusion -- References -- Chapter 14: Advanced Energy Devices -- Introduction -- Bipolar Vessel Sealing Systems -- Other Vessel Sealing Systems -- Ultrasonic Devices -- Challenges, Obstacles, and Misconceptions of Advanced Energy Devices -- Energy Devices in Remote Access Thyroid Surgery -- Future Directions: Radiofrequency Ablation -- Conclusion -- References -- Chapter 15: Parathyroid Gland Fluorescence Imaging -- The Need for Parathyroid Gland Identification and Assessment of Viability -- Parathyroid Gland Identification and Detection -- ICG -- Autofluorescence Imaging -- The Future of Fluorescence Imaging -- References -- Chapter 16: Intraoperative PTH Monitoring -- Historical Perspective -- Technical Considerations -- Assay Characteristics -- Source of Blood Samples -- Modern Application -- Previously Proposed Algorithms for Intraoperative Application of the PTH Assay -- Modern ioPTH Interpretation -- Interpretation of ioPTH in Renal Patients -- Novel Uses -- Tissue Aspirates: Preoperative and Intraoperative -- Bilateral IJ Sampling -- Final Considerations and Future Possibilities -- Changing Phenotype -- Faster Alternatives to the Rapid ioPTH -- References -- Part IV: Surgical Techniques -- Chapter 17: Minimally Invasive Video-Assisted Parathyroidectomy (MIVAP) and Minimally Invasive Video-Assisted Thyroidectomy (MIVAT). |
Minimally Invasive Video-Assisted Parathyroidectomy (MIVAP) -- Introduction -- The Technique -- Indications for MIVAP -- Advantages and Key Points of the Technique -- Limits and Drawbacks -- Minimally Invasive Video-Assisted Thyroidectomy (MIVAT) -- The Technique -- Indications -- Advantages of MIVAT -- Conclusion -- References -- Chapter 18: Robotic Transaxillary Thyroidectomy -- Introduction -- Patient Selection, Indications, and Contraindications -- Surgical Technique -- Postoperative Care and Complications -- Advantages and Disadvantages -- Future Directions -- References -- Chapter 19: Transoral Thyroidectomy -- Introduction -- Remote-Access Thyroid Surgery -- Overview -- Limitations of the Previously Described Remote-Access Thyroid Surgery -- Development of Transoral Thyroid Surgery -- The Value of Avoiding a Cervical Incision -- The Role of Robotic Surgical Systems in Transoral Thyroid Surgery -- Surgical Technique -- Limitations of TOETVA -- Future Directions -- References -- Part V: Postoperative Management -- Chapter 20: Ambulatory Endocrine Surgery -- Introduction -- Potential Benefits of Ambulatory Endocrine Surgery -- Ambulatory Thyroid Surgery -- Challenges and Risks of Ambulatory Thyroid Surgery -- Recurrent Laryngeal Nerve Injury and Risk of Aspiration -- Post-Thyroidectomy Neck Hematoma and Risk of Asphyxiation -- Hypoparathyroidism and Risk of Severe |
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Hypocalcemia and Tetany -- Postoperative Pain, Nausea, and Vomiting -- Ambulatory Parathyroid Surgery -- Conclusion -- References -- Chapter 21: Postoperative Calcium Management -- Introduction -- Patient and Disease Predisposing Risk Factors -- Signs and Symptoms of Hypocalcemia -- Monitoring of Postoperative PTH and Calcium Levels -- Prognostication of Postoperative Hypoparathyroidism/Hypocalcemia -- Management of Postoperative Hypoparathyroidism/Hypocalcemia -- Hungry Bone Syndrome. |
Conclusion. |
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