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1. |
Record Nr. |
UNINA9910810531803321 |
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Autore |
Apelgren Janne |
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Titolo |
Around the world in 80 dinners / / Janne Apelgren, Joanna Savill |
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Pubbl/distr/stampa |
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Carlton, Victoria, Australia : , : Melbourne University Press, , 2016 |
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ISBN |
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Descrizione fisica |
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1 online resource (401 pages) |
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Disciplina |
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Soggetti |
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Restaurants |
Voyages and travels |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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2. |
Record Nr. |
UNINA9910823465003321 |
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Autore |
Levitan Irena |
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Titolo |
Cholesterol Regulation of Ion Channels and Receptors |
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Pubbl/distr/stampa |
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ISBN |
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9786613721150 |
9781280879845 |
128087984X |
9781118342305 |
1118342305 |
9781118342312 |
1118342313 |
9781118342282 |
1118342283 |
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Edizione |
[1st ed.] |
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Descrizione fisica |
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1 online resource (324 p.) |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Cholesterol - metabolism |
Cholesterol -- metabolism |
Ion Channels - metabolism |
Ion Channels -- metabolism |
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Membrane Proteins - metabolism |
Membrane Proteins -- metabolism |
Cholesterol - Metabolism |
Ion channels - Metabolism |
Membrane proteins - Metabolism |
Proteins |
Membrane Glycoproteins |
Sterols |
Membrane Transport Proteins |
Metabolism |
Cholestenes |
Amino Acids, Peptides, and Proteins |
Carrier Proteins |
Cholestanes |
Membrane Lipids |
Lipids |
Steroids |
Pharmaceutical Preparations |
Polycyclic Compounds |
Cholesterol |
Ion Channels |
Membrane Proteins |
Human Anatomy & Physiology |
Health & Biological Sciences |
Animal Biochemistry |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di contenuto |
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CHOLESTEROL REGULATION OF ION CHANNELS AND RECEPTORS; CONTENTS; FOREWORD; PREFACE; CONTRIBUTORS; I CHOLESTEROL REGULATION OF MEMBRANE PROPERTIES; 1 CHOLESTEROL TRAFFICKING AND DISTRIBUTION BETWEEN CELLULAR MEMBRANES; 1.1 CHOLESTEROL-AN ESSENTIAL LIPID FOR NORMAL CELL FUNCTION; 1.2 CHOLESTEROL METABOLISM, SENSING, AND DISTRIBUTION BETWEEN CELLULAR MEMBRANES; 1.3 HOW DOES CHOLESTEROL ENTER MAMMALIAN CELLS?; 1.4 VESICULAR CHOLESTEROL TRAFFICKING ALONG THE ENDOCYTIC AND SECRETORY PATHWAY; 1.5 NONVESICULAR CHOLESTEROL TRANSPORT; 1.6 CHOLESTEROL EFFLUX FROM CELLS; REFERENCES |
2 CHOLESTEROL REGULATION OF MEMBRANE PROTEIN FUNCTION BY CHANGES IN BILAYER PHYSICAL PROPERTIES-AN ENERGETIC PERSPECTIVE2.1 INTRODUCTION; 2.2 CHOLESTEROL REGULATION OF MEMBRANE PROTEINS: POSSIBLE MECHANISMS; 2.3 PROTEIN REGULATION BY CHOLESTEROL-INDUCED CHANGES IN BILAYER PHYSICAL PROPERTIES; 2.4 CHOLESTEROL-INDUCED CHANGES IN DGIII bilayer - QUANTITATIVE ESTIMATES; 2.5 METHODS FOR IDENTIFYING PROTEIN REGULATION BY CHANGES IN BILAYER PHYSICAL PROPERTIES; |
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2.6 CHOLESTEROL REGULATION OF MEMBRANE PROTEINS IN LIVING CELLS |
2.7 PHYSIOLOGICAL ROLE OF CHOLESTEROL-INDUCED CHANGES IN BILAYER PHYSICAL PROPERTIES2.8 CONCLUSION; REFERENCES; II CHOLESTEROL REGULATION OF ION CHANNELS; 3 INSIGHTS INTO STRUCTURAL DETERMINANTS OF CHOLESTEROL SENSITIVITY OF KIR CHANNELS; 3.1 INTRODUCTION; 3.2 CHOLESTEROL SUPPRESSES Kir2 ACTIVITY IN VITRO AND IN VIVO; 3.3 EVIDENCE FOR SPECIFIC STEROL-PROTEIN INTERACTIONS IN THE REGULATION OF Kir CHANNELS; 3.4 STRUCTURAL DETERMINANTS OF CHOLESTEROL SENSITIVITY OF Kir2 CHANNELS; 3.5 PHYSIOLOGICAL IMPACT OF CHOLESTEROL-INDUCED SUPPRESSION OF KIR2 CHANNELS |
3.6 CONCLUDING REMARKS AND FUTURE DIRECTIONSACKNOWLEDGMENTS; REFERENCES; 4 ROLE OF LIPID RAFTS IN THE REGULATION OF STORE-OPERATED CA2+ CHANNELS; 4.1 INTRODUCTION; 4.2 MOLECULAR COMPONENTS OF SOCE; 4.3 LIPID RAFT DOMAINS AND CAVEOLAE; 4.4 THE ROLE OF LIPID RAFT DOMAINS IN THE REGULATION OF TRPC1; 4.5 MOLECULAR COMPLEXITY IN THE REGULATION OF SOCE; 4.6 CONCLUSIONS; REFERENCES; 5 CHOLESTEROL REGULATION OF CARDIAC ION CHANNELS; 5.1 INTRODUCTION; 5.2 EFFECT OF CHOLESTEROL ON CARDIAC EXCITABILITY; 5.3 MECHANISMS OF CHOLESTEROL EFFECTS ON ION CHANNELS |
5.4 CHOLESTEROL AS A TARGET FOR THERAPEUTIC AGENTSREFERENCES; 6 DIFFERENTIAL CONTRIBUTION OF BK SUBUNITS TO NONGENOMIC REGULATION OF CHANNEL FUNCTION BY STEROIDS; 6.1 BK CHANNELS AND STEROIDS; 6.2 CONCLUSIONS; ACKNOWLEDGMENTS; REFERENCES; 7 REGULATION OF K+ CHANNELS BY CHOLESTEROL-RICH MEMBRANE DOMAINS IN THE IMMUNE SYSTEM; 7.1 POTASSIUM CHANNELS IN THE IMMUNE SYSTEM; 7.2 REGULATION OF POTASSIUM CHANNELS BY MEMBRANE CHOLESTEROL AND LIPID RAFT MICRODOMAINS; 7.3 LOCALIZATION OF MAJOR VOLTAGE-DEPENDENT Kv1.3 AND Kv1.5 CHANNELS IN CHOLESTEROL-RICH MEMBRANE MICRODOMAINS IN LEUKOCYTES |
7.4 MECHANISMS OF ION CHANNEL REGULATION: THE IMMUNOLOGICAL SYNAPSE |
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Sommario/riassunto |
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Examines new research on the role of cholesterol in regulating ion channels and receptors and its effect on health Drawing together and analyzing all the latest research findings, this book explores the role of cholesterol in the regulation of ion channels and receptors, including its pathological effects. It is the first book to comprehensively describe the complex mechanisms by which cholesterol regulates two major classes of membrane proteins. Moreover, it sheds new light on how cholesterol affects essential cellular functions such as the contraction of the heart, propagatio |
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3. |
Record Nr. |
UNINA9910484919803321 |
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Titolo |
Software Process and Product Measurement : International Conferences IWSM 2009 and Mensura 2009 Amsterdam, The Netherlands, November 4-6, 2009. Proceedings / / edited by Alain Abran, René Braungarten, Reiner R. Dumke, Juan J. Cuadrado-Gallego, Jacob Brunekreef |
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Pubbl/distr/stampa |
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Berlin, Heidelberg : , : Springer Berlin Heidelberg : , : Imprint : Springer, , 2009 |
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ISBN |
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Edizione |
[1st ed. 2009.] |
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Descrizione fisica |
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1 online resource (XIII, 347 p.) |
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Collana |
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Programming and Software Engineering, , 2945-9168 ; ; 5891 |
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Classificazione |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Software engineering |
Computer science |
Computer systems |
Electronic digital computers - Evaluation |
Computer programming |
Software Engineering |
Theory of Computation |
Computer System Implementation |
System Performance and Evaluation |
Programming Techniques |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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International conference proceedings. |
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Nota di contenuto |
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IWSM / Mensura 2009 Proceedings -- Ensuring Reliability of Information Provided by Measurement Systems -- Analysis of the Functional Size Measurement Methods Usage by Polish Business Software Systems Providers -- Leveraging People-Related Maturity Issues for Achieving Higher Maturity and Capability Levels -- A General Model for Measurement Improvement -- What Are the Significant Cost Drivers for COSMIC Functional Size Based Effort Estimation? -- Analysis of the Risk Assessment Methods – A Survey -- Cockpit Based Management Architectures -- A Case Study in COSMIC Functional Size Measurement: The Rice Cooker Revisited -- Functional Size of a Real- |
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Time System -- A Prototypical Simulation Model to Analyze the Business Process Performance -- Improvement Opportunities and Suggestions for Benchmarking -- Functional Size Measurement Quality Challenges for Inexperienced Measurers -- Applying Test Case Metrics in a Tool Supported Iterative Architecture and Code Improvement Process -- Towards an Early Software Effort Estimation Based on Functional and Non-Functional Requirements -- Formalization Studies in Functional Size Measurement: How Do They Help? -- Using Models to Develop Measurement Systems: A Method and Its Industrial Use -- Evaluating Process Quality Based on Change Request Data – An Empirical Study of the Eclipse Project -- Empirical Evaluation of Hunk Metrics as Bug Predictors -- Using Support Vector Regression for Web Development Effort Estimation -- A Comparison of Neural Network Model and Regression Model Approaches Based on Sub-functional Components -- Formal Definition of Measures for BPMN Models -- Using Tabu Search to Estimate Software Development Effort -- An Experimental Study on the Reliability of COSMIC Measurement Results -- Assessing the Documentation Development Effort inSoftware Projects. |
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Sommario/riassunto |
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This book constitutes the refereed proceedings of two joint events - the International Workshop on Software Measurement, IWSM 2009 and the International Conference on Software Process and Product Measurement, Mensura 2009, held in Amsterdam, The Netherlands, in November 2009. The 24 revised full papers presented were carefully reviewed and selected from numerous submissions for inclusion in the book. This book considers issues such as the applicability of measures and metrics to software, the efficiency of measurement programs in industry and the theoretical foundations of software engineering. |
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