1.

Record Nr.

UNINA9910484137403321

Autore

Held Leonhard

Titolo

Likelihood and bayesian Inference : with applications in biology and medicine / / by Leonhard Held, Daniel Sabanés Bové

Pubbl/distr/stampa

Berlin, Heidelberg : , : Springer-Verlag, , 2020

ISBN

9783662607923

3-662-60792-1

Edizione

[Second edition]

Descrizione fisica

1 online resource (XIII, 402 pages, 84 illustrations)

Collana

Statistics for Biology and Health, , 2197-5671

Disciplina

570.15195

Soggetti

Biometry

Statistics

Ecology

Population genetics

Biostatistics

Statistical Theory and Methods

Bayesian Inference

Theoretical and Statistical Ecology

Population Genetics

Estadística bayesiana

Estadística matemàtica

Biometria

Estadística mèdica

Probabilitats

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Sommario/riassunto

This richly illustrated textbook covers modern statistical methods with applications in medicine, epidemiology and biology. Firstly, it discusses the importance of statistical models in applied quantitative research and the central role of the likelihood function, describing likelihood-based inference from a frequentist viewpoint, and exploring the properties of the maximum likelihood estimate, the score function, the



likelihood ratio and the Wald statistic. In the second part of the book, likelihood is combined with prior information to perform Bayesian inference. Topics include Bayesian updating, conjugate and reference priors, Bayesian point and interval estimates, Bayesian asymptotics and empirical Bayes methods. It includes a separate chapter on modern numerical techniques for Bayesian inference, and also addresses advanced topics, such as model choice and prediction from frequentist and Bayesian perspectives. This revised edition of the book “Applied Statistical Inference” has been expanded to include new material on Markov models for time series analysis. It also features a comprehensive appendix covering the prerequisites in probability theory, matrix algebra, mathematical calculus, and numerical analysis, and each chapter is complemented by exercises. The text is primarily intended for graduate statistics and biostatistics students with an interest in applications.