Record Nr.

UNINA9910484132203321

Titolo

Nanotechnology for bioapplications / / Bong-Hyun Jun, editor

Pubbl/distr/stampa


Singapore : , : Springer, , [2021]
©2021

ISBN

981-336-158-1

Descrizione fisica

1 online resource (vi, 292 pages) : illustrations

Collana

Advances in experimental medicine and biology ; ; Volume 1309

Disciplina

620.5

Soggetti

Nanobiotechnology

Ultraestructura (Biologia)

Llibres electrònics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references.

Nota di contenuto

Intro -- Contents -- 1: Introduction of Nanobiotechnology -- 1.1 Introduction -- 1.2 What Is Nanotechnology? -- 1.2.1 How Small Is Nano? -- 1.2.2 Nanofabrication and Analytical Tools -- 1.2.3 Exotic Properties of the Nanomaterials -- 1.3 Classification of Nanomaterials and Their Application -- 1.3.1 Metal NPs -- 1.3.2 Magnetic NPs -- 1.3.3 Quantum Dots (QDs) -- 1.3.4 Silica NPs -- 1.3.5 Carbon NPs -- 1.4 Nanotoxicology and Future Perspective -- Bibliography -- 2: General in Colloidal Nanoparticles -- 2.1 Introduction -- 2.2 Fabrication of Nanoparticles -- 2.2.1 Nucleation and Growth -- 2.2.1.1 Nucleation -- 2.2.1.2 Growth Kinetics -- 2.2.2 Size Control -- 2.2.2.1 Nucleation Control -- 2.2.2.2 Ostwald Ripening and Sintering -- 2.2.2.3 Microemulsion Method (Template-Based Method) -- 2.3 Stabilization of Nanocrystals Against Aggregation -- 2.3.1 Aggregation -- 2.3.2 Surface Charge -- 2.3.3 Electrical Double Layer -- 2.3.4 Van der Waals Attraction -- 2.3.5 DLVO (Derjaguin, Landau, Verwey, Overbeek) Theory -- 2.3.6 Steric Stabilization -- Bibliography -- 3: Silica Nanoparticles -- 3.1 Introduction -- 3.2 Synthesis of Silica Nanoparticles -- 3.2.1 Stöber Method (Nucleation and Growth) -- 3.2.2 Reverse Microemulsions -- 3.2.3 Modified Sol-Gel Method for Silica Coating -- 3.2.4 Modified Sol-Gel Method for Controlling Shape and Porosity -- 3.3 Surface Modification for Functionalization

of Silica Nanoparticles -- 3.4 Various Nanoparticles Applied to Silica -- 3.4.1 Various Silica-Coated Nanoparticles -- 3.4.2 Porous Silica Nanoparticles -- 3.4.3 Synthesis of Various Nanoparticles Using Silica as a Template -- 3.5 Various Silica-Applied Nanoparticles for Bioapplications -- 3.5.1 Biosensing and Bioimaging for Diagnostics -- 3.5.2 Drug Delivery -- 3.5.3 Multifunctional Silica Nanoparticles -- 3.6 Conclusion.

Bibliography -- 4: Luminescent Nanomaterials (I) -- 4.1 Introduction -- 4.2 Basics of Fluorescence -- 4.2.1 Light and Luminescence -- 4.2.2 Fluorescence Process and Related Terminologies -- 4.2.3 Organic Dyes As Fluorophores -- 4.3 Luminescent Nanoparticles -- 4.3.1 Fluorescence Organic Dye-Incorporated Materials -- 4.3.1.1 Dye-Doped Silica Nanoparticles -- 4.3.1.2 Fluorescence-Encoded Beads -- 4.3.2 Quantum Dots (QD) -- 4.3.2.1 Fundamentals of QDs -- Quantum Confinement Effect -- Optical Properties -- Quantum Yield and Surface Structures -- 4.3.2.2 Synthesis of Quantum Dots -- 4.3.2.3 Surface Modifications -- 4.3.3 Upconversion Fluorescent Nanoparticles -- 4.3.3.1 Fundamentals of UCNPs -- 4.3.3.2 Synthesis and Surface Modification of UCNPs -- 4.3.4 Other Luminescent Nanomaterials -- 4.3.4.1 Europium-Based Materials -- 4.3.4.2 Noble Metal Nanoclusters -- 4.3.4.3 Other Carbon-Based QDs -- References -- 5: Luminescent Nanomaterials (II) -- 5.1 Sensing Mechanisms and Techniques -- 5.1.1 Förster Resonance Energy Transfer (FRET) -- 5.1.2 Time-Resolved Fluorescence (TRF) -- 5.1.3 Flow Cytometry -- 5.2 Bioanalytical and Biomedical Application -- 5.2.1 Quantum Dot -- 5.2.2 UCNPs-Based Analysis -- 5.2.3 Europium-Based Analysis -- 5.3 Bioimaging -- 5.3.1 QD-Based Bioimaging -- 5.3.2 UCNPs-Based Imaging -- 5.3.3 Europium-Activated Luminescent Nanoprobes -- 5.3.4 NIR-II Imaging -- 5.4 Therapeutics Cooperated with Luminescent Nanoparticles -- 5.4.1 Drug Delivery -- 5.4.2 Photothermal Therapy -- 5.4.3 Photodynamic Therapy -- 5.5 Conclusions and Outlook -- References -- 6: Plasmonic Nanoparticles: Basics to Applications (I) -- 6.1 Introduction -- 6.2 Synthesis of Metal Nanoparticles -- 6.2.1 General Information -- 6.2.2 Citrate Reduction Method -- 6.2.3 Reverse Micelle Method -- 6.2.4 Polyol Method.

6.3 Property of Metal Nanoparticles -- 6.3.1 General Information -- 6.3.2 Localized Surface Plasmon Resonance -- 6.3.3 Effects of Size, Shape, Composition, and Environment -- 6.3.3.1 Size-Dependent Optical Property -- 6.3.3.2 Shape-Dependent Optical Property -- 6.3.3.3 Composition-Dependent Optical Property -- 6.3.3.4 Effect of Interactions with Mediums and Between NPs -- 6.4 Metal-Enhanced Process -- 6.4.1 Surface-Enhanced Fluorescence (SEF) -- 6.4.2 Surface-Enhanced Raman Scattering (SERS) -- 6.4.3 Plasmon Resonance Energy Transfer (PRET) -- 6.5 Basics for Biomedical Application of Metal Nanoparticles -- Bibliography -- 7: Plasmonic Nanoparticles: Advanced Researches (II) -- 7.1 Advanced Synthetic Researches -- 7.2 Recent Advanced Application in Biomedical Research -- 7.2.1 In Vitro Biosensors -- 7.2.2 Intracellular Detection and Ex Vivo/In Vivo Imaging -- 7.2.3 Therapeutic Applications -- 7.3 Conclusions and Outlook -- Bibliography -- 8: Magnetic Nanoparticles -- 8.1 Introduction -- 8.2 Synthesis of Magnetic Nanoparticles -- 8.2.1 General Information -- 8.2.2 Coprecipitation -- 8.2.3 Thermal Decomposition -- 8.2.3.1 New Type of Thermal Decomposition -- 8.2.4 Microemulsion -- 8.3 Physical Properties of Magnetic Nanoparticles -- 8.3.1 Units of Magnetic Property -- 8.3.2 Hysteresis Effect, Coercivity, and Remanence -- 8.3.3 Domain Theory -- 8.3.4 Magnetic Properties of Nanoparticles -- 8.3.5 Curie Temperature -- 8.4 Magnetism -- 8.4.1 Classification of Magnetism -- 8.4.2

Ferromagnetism -- 8.4.3 Ferrimagnetism -- 8.4.4 Superparamagnetism -- 8.5 Current Trends of Magnetic Nanoparticles -- 8.5.1 Separation/Purification of Biomolecules -- 8.5.2 Hyperthermia -- 8.5.3 Drug Delivery -- 8.5.4 Magnetic Resonance Imaging (MRI) -- 8.5.5 Multifunctional Nanocomposites Possessing Magnetic Property.

8.5.5.1 Multimodal Imaging -- 8.5.5.2 Theragnosis/Theragnostics -- Bibliography -- 9: Lithography Technology for Micro- and Nanofabrication -- 9.1 Introduction -- 9.2 Conventional Lithography -- 9.2.1 Photolithography -- 9.2.2 High-Energy Beam Lithography -- 9.2.2.1 Electron Beam Lithography -- 9.2.2.2 Focused Ion Beam Lithography -- 9.3 Unconventional Lithography -- 9.3.1 Nanoimprint Lithography (NIL) -- 9.3.1.1 Thermal NIL -- 9.3.1.2 UV-NIL -- 9.3.2 Deformation of Material-Based Lithography -- 9.3.2.1 Wrinkling -- 9.3.2.2 Cracking -- 9.3.2.3 Collapsing -- 9.3.3 Colloidal Lithography -- 9.3.3.1 Self-Assembly of Colloidal Particles -- 9.3.3.2 Colloidal Particle-Based Patterning -- 9.4 Overlook and Conclusions -- Bibliography -- 10: Bioapplications of Nanomaterials -- 10.1 Overview -- 10.2 Pharmaceutical Applications -- 10.2.1 Drug Delivery and Targeting Strategies -- 10.3 Biosensing and Biochips -- 10.3.1 SERS-Based Intracellular Biosensing -- 10.3.1.1 Gaseous Sensing -- 10.3.1.2 pH Sensing -- 10.3.1.3 Reactive Oxygen Species (ROS) -- 10.3.1.4 Redox Potential Sensing -- 10.3.2 Detection of Biomolecules by SERS -- 10.3.2.1 Proteins -- 10.3.2.2 DNA -- 10.3.2.3 Metabolite -- 10.3.2.4 Pathogens -- 10.4 Gene Delivery -- 10.5 Bioimaging -- 10.5.1 SERS-Based Cellular Imaging -- 10.5.2 Imaging of Cell Surface Species -- 10.5.3 Endocytic Pathway -- 10.5.4 Cell Cycle and Apoptotic Process -- 10.5.5 Cell Secretion -- 10.6 Cancer Diagnostics and Therapeutics -- Bibliography -- 11: Carbon Nanomaterials for Biomedical Application -- 11.1 Introduction -- 11.2 Properties of Carbon-Based Nanomaterials -- 11.2.1 Graphite and Fullerene -- 11.2.2 Carbon Nanotube -- 11.2.3 Graphene and Derivatives -- 11.3 Surface Functionalization of Carbon Nanomaterials -- 11.3.1 Noncovalent Surface Chemistry.

11.3.2 Covalent Surface Chemistry -- 11.4 Carbon Nanomaterials for Biological Applications -- 11.4.1 In Vitro Sensing Elements and Diagnostics -- 11.4.2 Graphene Nanopore and Graphene Liquid Cell -- 11.4.3 Functional 3D Carbon Nanomaterials -- 11.4.4 Photothermal Therapy -- 11.4.5 Tissue Engineering Using Carbon Materials -- 11.5 Conclusions and Outlook -- References -- 12: Optical and Electron Microscopy for Analysis of Nanomaterials -- 12.1 Introduction -- 12.2 Optical Microscopy -- 12.3 Electron Microscopy (EM) -- 12.3.1 Transmission Electron Microscopy (TEM) -- 12.3.2 Scanning Electron Microscopy (SEM) -- 12.4 Scanning Probe Microscopy (SPM) -- 12.4.1 Scanning Tunneling Microscopy (STM) -- 12.4.2 Atomic Force Microscopy (AFM) -- 12.4.3 Near-Field Scanning Optical Microscopy (NSOM) -- 12.5 Outlook and Summary -- References -- 13: Conclusion and Perspective -- 13.1 Conclusion -- 13.2 Perspective.