1.

Record Nr.

UNINA9910484096503321

Titolo

Non-neurogenic bladder dysfunctions / / Matteo Balzarro, Vincenzo Li Marzi, editors

Pubbl/distr/stampa

Singapore : , : Springer, , [2021]

©2021

ISBN

3-030-57393-1

Descrizione fisica

1 online resource (215 pages)

Collana

Urodynamics, Neurourology and Pelvic Floor Dysfunctions

Disciplina

616.62

Soggetti

Bladder - Diseases

Bufeta

Malalties de l'aparell urinari

Llibres electrònics

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Intro -- Foreword -- Preface -- Preface -- Contents -- 1: Physiopathology of Overactive Bladder -- 1.1  Definitions -- 1.2  Pathophysiology -- 1.3  Neurogenic Factors -- 1.4  Non-neurogenic Factors -- 1.4.1  Myogenic Factor -- 1.4.2  Urotheliogenic Factor -- 1.4.3  Bladder Outlet Obstruction -- 1.4.4  Bladder Ischemia -- 1.4.5  Inflammation -- 1.4.6  Gender -- 1.4.7  Psychological Factors -- References -- 2: Diagnosis of Overactive Bladder -- 2.1  The Initial Diagnostic Workup in the Uncomplicated OAB Patient -- 2.1.1  History -- 2.1.2  Physical Examination -- 2.1.3  Urinalysis and Urine Culture -- 2.1.4  Voiding Diaries and Pad Testing -- 2.1.5  Symptom Questionnaires and Scores -- 2.2  The Diagnostic Workup in the Complicated OAB Patient -- 2.2.1  Cystoscopy -- 2.2.2  Urinary Tract Ultrasound -- 2.2.3  Uroflowmetry -- 2.2.4  Urodynamic Test -- References -- 3: Treatment Options in Patients with Overactive Bladder: Initial and Pharmacological Management -- 3.1  Introduction -- 3.2  Initial Management of Overactive Bladder -- 3.2.1  Lifestyle Modification -- 3.3  Pharmacological Treatment of Overactive Bladder Symptoms -- 3.3.1  Antimuscarinics Drugs -- 3.3.1.1  Darifenacin Hydrobromide -- 3.3.1.2  Fesoterodine Fumarate -- 3.3.1.3  



Imidafenacin -- 3.3.1.4  Propantheline Bromide -- 3.3.1.5  Solifenacin Succinate -- 3.3.1.6  Tolterodine Tartrate -- 3.3.1.7  Trospium Chloride -- 3.3.1.8  Oxybutynin Chloride -- 3.3.1.9  Propiverine Hydrochloride -- 3.3.2  β-Adrenoceptor Agonists -- 3.3.2.1  Mirabegron -- 3.3.3  Antidepressants -- 3.3.3.1  Imipramine -- 3.4  Combination Therapy -- 3.5  Pharmacological Management of Patients with Overactive Bladder -- 3.5.1  Comorbidities -- 3.5.1.1  Glaucoma -- 3.5.1.2  Neurological Diseases -- 3.5.1.3  Cognitive Impairment -- 3.5.1.4  Associate BOO -- 3.5.1.5  Frail Older Patients -- References.

4: Treatment Options in Patients with Overactive Bladder: The Invasive Management -- 4.1  Introduction -- 4.2  Botulinum Toxin -- 4.2.1  Molecular Structure and Mechanism of Action -- 4.2.2  BoNTA Intradetrusor Injection -- 4.2.3  BoNTA Efficacy -- 4.2.4  Adverse Events -- 4.3  Sacral Neuromodulation (SNM) -- 4.3.1  Technique -- 4.3.2  Mechanism of Action -- 4.3.3  SNM Efficacy -- 4.3.4  Adverse Events -- 4.4  Percutaneous Tibial Nerve Stimulation -- 4.4.1  PTNS Technique and Efficacy -- 4.5  Major Surgery -- 4.5.1  Enterocystoplasty -- References -- 5: Bladder Outlet Obstruction and Overactive Bladder in Females -- 5.1  Lower Urinary Tract Symptoms' Epidemiology -- 5.2  Bladder Outlet Obstruction Pathophysiology -- 5.3  OAB Pathophysiology -- 5.4  Diagnosis -- 5.4.1  History -- 5.4.2  Physical Examination -- 5.4.3  Diagnostic Tools -- 5.5  Management -- 5.6  OAB Management -- 5.7  BOO Management -- References -- 6: Bladder Outlet Obstruction and Overactive Bladder in Males -- 6.1  Definition -- 6.2  Epidemiology -- 6.3  Pathophysology -- 6.4  Diagnosis -- 6.4.1  General Considerations -- 6.5  Management -- 6.5.1  General Considerations -- 6.6  Conservative Treatments -- 6.6.1  General Considerations -- 6.7  Pharmacological Treatments -- 6.7.1  General Considerations -- 6.7.2  α1-Blockers and 5α-Reductase -- 6.7.3  Antimuscarinic Agents and Beta-3 Adrenoreceptors -- 6.7.4  Phosphodiesterase 5 Inhibitors -- 6.7.5  Plant Extracts: Phytotherapy -- 6.8  Surgical Treatments -- 6.8.1  General Considerations -- References -- 7: Overactive Bladder and Female Stress Urinary Incontinence -- 7.1  An Overview on "Urethrogenic" Mixed Urinary Incontinence -- 7.2  A Counterview on "Urethrogenic" Mixed Urinary Incontinence -- References -- 8: Physiopathology of Underactive Bladder -- 8.1  Introduction and Definitions -- 8.2  Physiopathology.

8.2.1  Detrusor Muscle Activity Damage -- 8.2.2  Neurogenic Damage -- 8.2.3  Receptors Expression and Drugs -- 8.2.4  Idiopathic UAB -- 8.3  Aging -- 8.4  Fowler's Syndrome -- 8.5  Dysfunctional Voiding -- 8.6  Conclusions -- References -- 9: Diagnosis of Underactive Bladder in Male -- 9.1  Introduction -- 9.2  Clinical Findings -- 9.3  Urodynamic Testing -- 9.4  Conclusions -- References -- 10: Diagnosis of Underactive Bladder in Female -- 10.1  Diagnosis of Underactive Bladder in Females -- 10.2  Clinical Diagnosis -- 10.2.1  Medical History -- 10.2.2  Symptoms -- 10.2.3  Patient-Reported Outcomes -- 10.3  Urodynamics -- 10.3.1  Free Flow -- 10.3.2  Pressure/Flow Study -- 10.3.3  Detrusor Contraction Strength -- 10.3.3.1  Isovolumetric Detrusor Pressure -- 10.3.3.2  Watts Factor -- 10.3.3.3  Projected Isovolumetric Pressure (PIP) -- 10.3.4  Detrusor Contraction Velocity -- 10.3.5  The Role of Bladder Sensation -- 10.3.6  The Role of DO -- 10.4  Conclusion -- References -- 11: Treatment Options of Underactive Bladder -- 11.1  Conservative Management -- 11.2  Pharmacological Therapy -- 11.3  Minimally Invasive Treatment -- 11.4  Surgical Treatment -- 11.5  Conclusion -- References -- 12: Detrusor Overactivity with Detrusor Underactivity -- 12.1  Introduction -- 12.2  Etiology -- 12.3  Prevalence and Risk Factors -- 12.4  



Diagnosis -- 12.5  Treatment -- 12.6  Conclusion -- References -- 13: Defunctionalized Bladder and Kidney Transplantation -- 13.1  Introduction -- 13.2  Pathophysiology -- 13.3  Clinical and Urodynamic Characteristics -- 13.4  Outcomes and Complications -- 13.5  Conclusions -- References -- 14: Imaging in Bladder Dysfunctions -- 14.1  Introduction -- 14.2  Urogynecology -- 14.2.1  Bladder US Findings in Urogynecology -- 14.2.1.1  PVR -- 14.2.1.2  BWT -- 14.2.2  Extravesical US Findings in Urogynecology.

14.2.2.1  Urethral Hypermobility -- 14.2.2.2  Funneling -- 14.2.2.3  Pelvic Organ Prolapse (POP) -- 14.3  Male LUTS -- 14.3.1  Bladder US Findings in Male LUTS -- 14.3.1.1  PVR -- 14.3.1.2  BWT/DWT -- 14.3.1.3  UEBW -- 14.3.2  Prostate US Findings in Male LUTS -- 14.3.2.1  PCAR -- 14.3.2.2  IPP -- 14.3.2.3  PUA -- References -- 15: Female Sexuality in Pelvic Floor Disorders -- 15.1  Introduction and Epidemiology -- 15.2  Diagnosis -- 15.3  Screening Questionnaires -- 15.4  Screening for Sexual Activity and Function in Women with PFDs -- 15.5  Sexual Function in Specific Pelvic Floor Disorders -- 15.5.1  Pelvic Organ Prolapse -- 15.6  Nonsurgical Treatment of Pelvic Organ Prolapse -- 15.6.1  Pessaries -- 15.7  Surgical Treatment of Pelvic Organ Prolapse -- 15.7.1  Anterior and Posterior Repairs -- 15.7.2  Apical Repairs -- 15.8  Urinary Incontinence -- 15.9  Stress Urinary Incontinence -- 15.9.1  Pelvic Floor Physical Therapy (PFFT) -- 15.9.2  Colposuspension and Midurethral Slings -- 15.10  Urinary Urgency Incontinence and Overactive Bladder -- 15.10.1  Oral Medications -- 15.10.2  Neuromodulation -- 15.10.3  Intra-detrusor Botulinum Toxin A (Botox) -- 15.11  Anal and Fecal Incontinence -- 15.12  Surgical Treatment of Fecal Incontinence -- 15.12.1  Sphincteroplasty -- 15.12.2  Neuromodulation and Botox -- 15.13  Conclusion -- References -- Index.