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Record Nr. |
UNINA9910483977303321 |
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Titolo |
Immunotherapy - a novel facet of modern therapeutics / / edited by Sujata P. Sawarkar, Vandana S. Nikam, Shariq Syed |
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Pubbl/distr/stampa |
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Singapore : , : Springer, , [2021] |
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©2021 |
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ISBN |
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Edizione |
[1st ed. 2021.] |
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Descrizione fisica |
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1 online resource (VIII, 262 p. 15 illus., 12 illus. in color.) |
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Disciplina |
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Soggetti |
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Cancer - Research |
Human physiology |
Immunotherapy |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Chapter 1. Immunotherapy – a Concept -- Chapter 2. Immunotherapy in Cancer - Immune Checkpoint Inhibitors; changing Oncology treatment paradigm -- Chapter 3. Vaccines as Immunotherapy -- Chapter 4. Immunotherapy for Autoimmune Diseases -- Chapter 5. Immunotherapy in neurodegenerative disorders -- Chapter 6. Companion diagnostics and clinical biomarkers for immunotherapy -- Chapter 7. Novel Drug Delivery Systems for Immunotherapeutics -- Chapter 8. Discovery, Screening Methods, Design Considerations and Scale-up aspects of Immunotherapeutic Drugs -- Chapter 9. Pharmacokinetics, Pharmacodynamics, and Toxicology aspects of Immunotherapeutics -- Chapter 10. Regulatory Affairs and Intellectual Property Rights in Immunotherapeutics -- Chapter 11. Future immunotherapy challenges and perspectives. . |
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Sommario/riassunto |
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This book illustrates the significance and relevance of immunotherapy in modern-day therapeutics. Focusing on the application of immunotherapy in oncology, neurodegenerative and autoimmune diseases, it discusses the drug delivery systems, and pre-clinical and clinical methodologies for immunotherapy-based drugs. It also comprehensively reviews various aspects of immunotherapy, such as regulatory affairs, quality control, safety, and pharmacovigilance. |
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Further, the book discusses the in vitro validation of therapeutic strategies prior to patient application and management of immunotherapy-related side effects and presents case studies demonstrating the design and development (pre-clinical to clinical) of immunotherapy for various diseases. It also describes various design considerations and the scale-up synthesis of immunotherapeutics and screening methods. Lastly, it explores the important aspect of cost-effectiveness and rational immunotherapy strategies. . |
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