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1. |
Record Nr. |
UNINA9910482992303321 |
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Autore |
Jośī R̥cā |
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Titolo |
Collagen biografts for tunable drug delivery / / Rucha Joshi |
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Pubbl/distr/stampa |
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Cham, Switzerland : , : Springer, , [2021] |
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©2021 |
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ISBN |
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Edizione |
[1st ed. 2021.] |
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Descrizione fisica |
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1 online resource (XII, 107 p. 41 illus., 30 illus. in color.) |
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Collana |
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SpringerBriefs in Applied Sciences and Technology |
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Disciplina |
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Soggetti |
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Collagen - Therapeutic use |
Biomedical materials - Therapeutic use |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Nota di contenuto |
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Introduction -- Creating Tunable Collagen Matrices - An Approach Inspired by In-Vivo Collagen Synthesis and Self-Assembly -- Application of Collagen Fibril Biografts for Enhancing Local Vascularization in an In-Vivo Chick Chorioallantoic Membrane (CAM) Model -- Appendix A: Type I Collagen Based Drug Delivery Formats -- Appendix B: State-of-the-Art Methods of Tuning Collagen Based Molecular Release. |
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Sommario/riassunto |
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This book reviews collagen-based biomaterials that have been applied broadly to tissue engineering and local drug delivery applications and lays out a landscape for developing a multifunctional biograft material from collagen polymers. The book also discusses current shortcomings in collagen based drug delivery opportunities, including poor mechanical properties, rapid proteolytic degradation, and cursory control over physical properties and molecular release profiles. Finally, a review of application of the collagen biograft materials for promoting neovascularization and tissue regeneration is presented, using examples of established in-vivo chicken egg chorioallantoic membrane (CAM) model. Use of heparin for affinity-based vascular endothelial growth factor (VEGF) retention in collagen constructs is also discussed for promoting neovascularization. Reviews state-of-the-art strategies for drug incorporation and retention in collagen ; Covers collagen based material applications for improving vascularization and tissue |
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regeneration; Illustrates how to tailor collagen architecture for soft tissue engineering and controlled drug delivery. |
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2. |
Record Nr. |
UNINA9910711504503321 |
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Titolo |
Assessing the effectiveness of the Transitional Program for Covered Business Method Patents : hearing before the Subcommittee on Courts, Intellectual Property, and the Internet of the Committee on the Judiciary, House of Representatives, One Hundred Fifteenth Congress, second session, March 20, 2018 |
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Pubbl/distr/stampa |
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Washington : , : U.S. Government Publishing Office, , 2018 |
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Descrizione fisica |
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1 online resource (iii, 18 pages) |
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Soggetti |
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Business method patents - United States |
Patent infringement - United States - Prevention |
Patent laws and legislation - United States |
Business method patents |
Evaluation |
Patent laws and legislation |
Online resources. |
Legislative hearings. |
United States |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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