1.

Record Nr.

UNINA9910482992303321

Autore

Jośī R̥cā

Titolo

Collagen biografts for tunable drug delivery / / Rucha Joshi

Pubbl/distr/stampa

Cham, Switzerland : , : Springer, , [2021]

©2021

ISBN

3-030-63817-0

Edizione

[1st ed. 2021.]

Descrizione fisica

1 online resource (XII, 107 p. 41 illus., 30 illus. in color.)

Collana

SpringerBriefs in Applied Sciences and Technology

Disciplina

610.284

Soggetti

Collagen - Therapeutic use

Biomedical materials - Therapeutic use

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di contenuto

Introduction -- Creating Tunable Collagen Matrices - An Approach Inspired by In-Vivo Collagen Synthesis and Self-Assembly -- Application of Collagen Fibril Biografts for Enhancing Local Vascularization in an In-Vivo Chick Chorioallantoic Membrane (CAM) Model -- Appendix A: Type I Collagen Based Drug Delivery Formats -- Appendix B: State-of-the-Art Methods of Tuning Collagen Based Molecular Release.

Sommario/riassunto

This book reviews collagen-based biomaterials that have been applied broadly to tissue engineering and local drug delivery applications and lays out a landscape for developing a multifunctional biograft material from collagen polymers. The book also discusses current shortcomings in collagen based drug delivery opportunities, including poor mechanical properties, rapid proteolytic degradation, and cursory control over physical properties and molecular release profiles. Finally, a review of application of the collagen biograft materials for promoting neovascularization and tissue regeneration is presented, using examples of established in-vivo chicken egg chorioallantoic membrane (CAM) model. Use of heparin for affinity-based vascular endothelial growth factor (VEGF) retention in collagen constructs is also discussed for promoting neovascularization. Reviews state-of-the-art strategies for drug incorporation and retention in collagen ; Covers collagen based material applications for improving vascularization and tissue



regeneration; Illustrates how to tailor collagen architecture for soft tissue engineering and controlled drug delivery.

2.

Record Nr.

UNINA9910711504503321

Titolo

Assessing the effectiveness of the Transitional Program for Covered Business Method Patents : hearing before the Subcommittee on Courts, Intellectual Property, and the Internet of the Committee on the Judiciary, House of Representatives, One Hundred Fifteenth Congress, second session, March 20, 2018

Pubbl/distr/stampa

Washington : , : U.S. Government Publishing Office, , 2018

Descrizione fisica

1 online resource (iii, 18 pages)

Soggetti

Business method patents - United States

Patent infringement - United States - Prevention

Patent laws and legislation - United States

Business method patents

Evaluation

Patent laws and legislation

Online resources.

Legislative hearings.

United States

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"Serial no. 115-54."