| |
|
|
|
|
|
|
|
|
1. |
Record Nr. |
UNINA9910466108203321 |
|
|
Autore |
Roberts Michael F. |
|
|
Titolo |
Receptor biology / / Michael F. Roberts and Anne E. Kruhchten |
|
|
|
|
|
Pubbl/distr/stampa |
|
|
Weinheim, Germany : , : Wiley-VCH Verlag GmBH & Company KGaA, , [2016] |
|
©2016 |
|
|
|
|
|
|
|
|
|
ISBN |
|
|
|
|
|
|
Descrizione fisica |
|
1 online resource (478 p.) |
|
|
|
|
|
|
Soggetti |
|
Cell receptors |
Nuclear receptors (Biochemistry) |
Binding sites (Biochemistry) |
Ligands (Biochemistry) |
Electronic books. |
|
|
|
|
|
|
|
|
Lingua di pubblicazione |
|
|
|
|
|
|
Formato |
Materiale a stampa |
|
|
|
|
|
Livello bibliografico |
Monografia |
|
|
|
|
|
Note generali |
|
Description based upon print version of record. |
|
|
|
|
|
|
Nota di bibliografia |
|
Includes bibliographical references and index. |
|
|
|
|
|
|
Nota di contenuto |
|
Title Page; Copyright; Dedication; Table of Contents; Acknowledgments; Part I: Introduction; Chapter 1: Introduction; 1.1 Receptors and Signaling; 1.2 Types of Receptors and Hormones; 1.3 Receptors Are the Chemical Expression of Reality; Chapter 2: The Origins of Chemical Thinking; 2.1 Overview of Early Pharmacological History; 2.2 Modern Pharmacology; 2.3 Phylogenetics of Signaling; Part II: Fundamentals; Chapter 3: Membranes and Proteins; 3.1 Membranes; 3.2 The Nature and Function of Proteins; Chapter 4: Hormones as First Messengers; 4.1 Hormones and Cellular Communication |
4.2 Types of Hormones4.3 Vertebrate Hormones and Transmitters; 4.4 Analgesics and Venoms as Receptor Ligands; Chapter 5: Receptor Theory; 5.1 The Materialization of Receptors; 5.2 Receptor Mechanisms; 5.3 Binding Theory; 5.4 Visualizing Receptor Structure and Function; 5.5 Proteomics Approaches to Receptor Efficacy; 5.6 Physical Factors Affecting Receptor Binding; Part III: Receptor Types and Function; Chapter 6: Transduction I: Ion Channels and Transporters; 6.1 Introduction; 6.2 Small Molecule Channels; 6.3 Transporters; 6.4 Major Intrinsic Proteins; 6.5 Ligand-Gated Ion Channels |
|
|
|
|
|
|
|
|
|
|
Chapter 7: Transduction II: G-Protein-Coupled Receptors7.1 Introduction; 7.2 Families of G-Protein-Coupled Receptors; 7.3 Transduction Mechanisms; 7.4 The Major Families of G Protein-Coupled Receptors; Chapter 8: Transduction III: Receptor Kinases and Immunoglobulins; 8.1 Protein Kinases; 8.2 Receptors for Cell Division and Metabolism; 8.3 Receptor Serine/Threonine Kinases; 8.4 The Guanylyl Cyclase Receptor Subfamily - Natriuretic Peptide Receptors; 8.5 Non-Kinase Molecules - LDL Receptors; 8.6 Cell-Cell Contact Signaling; 8.7 Immune System Receptors, Antibodies, and Cytokines |
Chapter 9: Transduction IV: Nuclear Receptors9.1 Introduction; 9.2 Genomic Actions of Nuclear Receptors; 9.3 Actions of Receptor Antagonists; 9.4 Non-Traditional Actions of Steroid-Like Hormones and Their Receptors; Part IV: Applications; Chapter 10: Signaling Complexity; 10.1 Introduction; 10.2 Experimental Determination of Signaling Cascades; 10.3 Transduction across the Membrane; 10.4 Complexity in Cross Talk - Roles of PIP3, Akt, and PDK1; 10.5 Role in Cancer; 10.6 Signaling Mediated by Gas Molecules; Chapter 11: Cellular Interactions in Development; 11.1 Introduction |
11.2 The Origins of Multicellularity11.3 The Origin of Symmetry and Axes; 11.4 Fertilization and Organization of the Multicellular Body Plan; 11.5 Differentiation of Triploblastic Embryos - Organogenesis; 11.6 Programmed Cell Death (Apoptosis); Chapter 12: Receptor Mechanisms in Disease Processes; 12.1 Genetic Basis for Receptor Function; 12.2 Receptor Pathologies; 12.3 Signaling Mutations Leading to Cancer; Chapter 13: Receptors and the Mind; 13.1 Origins of Behavior; 13.2 Nervous Systems; 13.3 Animal Memory: Invertebrates; 13.4 Animal Memory: Vertebrates |
13.5 Receptors and Behavior: Addiction, Tolerance, and Dependence |
|
|
|
|
|
| |