1.

Record Nr.

UNINA9910458163303321

Autore

Knowles Margaret A

Titolo

Introduction to the cellular and molecular biology of cancer [[electronic resource] /] / Margaret A. Knowles, Peter J. Selby

Pubbl/distr/stampa

New York, : Oxford University Press, 2005

ISBN

1-280-75813-9

0-19-151381-4

1-4294-2155-X

Edizione

[4th ed.]

Descrizione fisica

1 online resource (555 p.)

Altri autori (Persone)

SelbyP (Peter)

Disciplina

616.99/4071

Soggetti

Cancer - Molecular aspects

Cancer cells

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Note generali

"Oxford bioscience"--Cover.

Nota di contenuto

Contents; Contributors; 1 What is cancer?; 2 The causes of cancer; 3 Inherited susceptibility to cancer; 4 DNA repair and cancer; 5 Epigenetic events in cancer; 6 Molecular cytogenetics of cancer; 7 Oncogenes; 8 Tumour suppressor genes; 9 The cancer cell cycle; 10 Cellular immortalization and telomerase activation in cancer; 11 Growth factors and their signalling pathways in cancer; 12 Apoptosis: molecular physiology and significance for cancer therapeutics; 13 Mechanisms of viral carcinogenesis; 14 Cytokines and cancer; 15 Hormones and cancer; 16 The spread of tumours; 17 Tumour angiogenesis

18 Stem cells, haemopoiesis, and leukaemia19 Animal models of cancer; 20 The immunology of cancer; 21 The molecular pathology of cancer; 22 From transcriptome to proteome; 23 Local treatment of cancer; 24 Chemotherapy; 25 Radiotherapy and molecular radiotherapy; 26 Monoclonal antibodies and therapy; 27 Immunotherapy of cancer; 28 Cancer gene therapy; 29 Screening; 30 Conclusions and prospects; Index

Sommario/riassunto

. What is cancer?, L.M. Franks and Margaret A. Knowles. 2. The causes of cancer, Naomi Allen, Robert Newton, Amy Berrington de Gonzalez, Jane Green, Emily Banks, and Timothy J. Key. 3. Inherited Susceptibility



to Cancer, D. Timothy Bishop. 4. DNA Repair and Cancer, Beate Koberle, John P. Wittschieben, and Richard D. Wood. 5. Epigenetic Events in Cancer, Jonathan C. Cheng and Peter A. Jones. 6. Molecular Cytogenetics of Cancer, Denise. Sheer and Janet Shipley. 7. Oncogenes, Margaret A. Knowles. 8. Tumour suppressor genes, Sonia Lain and David P. Lane. 9. The cancer cell cycle, Chris J. Norbury.

2.

Record Nr.

UNINA9910466022103321

Autore

Adelson Leslie A.

Titolo

Cosmic miniatures and the future sense : Alexander Kluge's 21st-century literary experiments in German culture and narrative form / / Leslie A. Adelson

Pubbl/distr/stampa

Berlin, [Germany] ; ; Boston, [Massachusetts] : , : De Gruyter, , 2017

©2017

ISBN

3-11-052432-5

3-11-052564-X

Descrizione fisica

1 online resource (304 pages)

Collana

Interdisciplinary German Cultural Studies, , 1861-8030 ; ; Volume 22

Disciplina

791.450232092

Soggetti

Future, The, in literature

Time in literature

Experimentelle Prosa

Literarische Form

SOCIAL SCIENCE / General

Electronic books.

Lingua di pubblicazione

Inglese

Formato

Materiale a stampa

Livello bibliografico

Monografia

Nota di bibliografia

Includes bibliographical references and indexes.

Nota di contenuto

Frontmatter -- Acknowledgements -- Contents -- Introduction: Hope in Time -- Part One: Cosmic Miniatures and Critical Horizons: Exercising the Future Sense -- Part Two: Global Miniatures and Marxist Horizons: Conjunctions in Narrative Time -- Part Three: German Miniatures and Perspectival Horizons: Recalibrating Historical Voice -- Postscript: Futurity as Fairy Tale? From Flaschenpost to Nachricht and More -- Works Cited -- Alphabetical List of Kluge Titles Discussed, in



German and English -- Index of Persons -- Index of Works -- Index of Terms

Sommario/riassunto

Alexander Kluge's revolutionary storytelling for the 21st-century pivots on the production of anti-realist hope under conditions of real catastrophe. Rather than relying on possibility alone, his experimental miniatures engender counterfactual horizons of futurity that are made incrementally accessible to lived experience through narrative form. Innovative close readings and theoretical reflection alike illuminate the dimensional quality of future time in Kluge's radical prose, where off-worldly orientation and unnatural narrative together yield new sensory perspectives on associative networks, futurity, scale, and perspective itself. This study also affords new perspectives on the importance of Kluge's creative writing for critical studies of German thought (including Kant, Marx, Benjamin, and especially Adorno), Holocaust memory, contemporary globalization, literary miniatures, and narrative studies of futurity as form. Cosmic Miniatures contributes an experiential but non-empirical sense of hope to future studies, a scholarly field of pressing public interest in endangered times.