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1. |
Record Nr. |
UNINA9910465429503321 |
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Titolo |
Aggressive breast cancer [[electronic resource] /] / Regina H. DeFrina, editor |
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Pubbl/distr/stampa |
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New York, : Nova Science Publishers, c2010 |
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ISBN |
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Descrizione fisica |
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1 online resource (276 p.) |
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Collana |
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Cancer etiology, diagnosis and treatments series |
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Altri autori (Persone) |
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Disciplina |
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Soggetti |
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Breast - Cancer |
Breast - Diseases |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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""AGGRESSIVE BREAST CANCER ""; ""AGGRESSIVE BREAST CANCER ""; ""CONTENTS ""; ""PREFACE""; ""RESEARCH AND REVIEW ARTICLES""; ""THE HER2 ONCOGENE IN BREAST CANCER ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""HER PROTEIN RECEPTORS: SIGNAL TRANSDUCTION AND ONCOGENESIS ""; ""Intracellular Signaling Pathways ""; ""HER-Induced Cell Cycle Progression and Survival Pathways ""; ""OVER EXPRESSION OF HER2 AND THE PROGNOSIS OF INVASIVE BREAST CANCER ""; ""HER2 as A Prognostic Factor: Node-Positive Versus Node-Negative Disease""; ""HER Status and Lymphoid Infiltration "" |
""HER2 and Progression of Early Breast Cancer Lesions to Invasive Carcinomas""""Relationship Between HER2 and Estrogen Receptor Expression ""; ""HER2 ABNORMALITIES IN OTHER TYPES OF BREAST MALIGNANCIES ""; ""HER2 ABNORMALITIES IN OTHER TYPES OF BREAST MALIGNANCIES ""; ""Evaluating HER2 in Breast Tissue ""; ""HER2 TARGETED THERAPY IN BREAST CANCER ""; ""The Role of Trastuzumab in HER2 Overexpressing Breast Cancer ""; ""The Role of Pertuzumab in HER2 Overexpressing Breast Cancer ""; ""The Role of Trastuzumab-DM1 in HER2 Overexpressing Breast Cancer "" |
""Inhibiting Several HER Receptors: The Role of Lapatinib in HER2 Overexpressing Breast Cancer """"Circulating Serum HER2 Levels ""; ""PROPOSED RESISTANCE TO ANTI-HER2 THERAPIES ""; ""Altered |
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Receptor-Antibody Interaction ""; ""Increased Signaling from other Receptors of the HER Family ""; ""Increased Signaling from other Receptors Activating the MAPK and PI3K Pathways ""; ""Constitutive Activation of Downstream Effectors ""; ""HER2 OVEREXPRESSION AND CHEMOTHERAPY ""; ""Anthracyclines ""; ""Taxanes ""; ""HER2 OVEREXPRESSION AND HORMONAL THERAPY "" |
""CNS DISEASE IN HER2 OVEREXPRESSED BREAST CANCER """"CNS Metastases in Adjuvant Trials of Trastuzumab ""; ""Prognosis of CNS Metastases in HER2 Overexpressing Breast Cancer""; ""CONCLUSION ""; ""REFERENCES""; ""MULTI-DRUG RESISTANCE AS A PROBLEM CHALLENGING BREAST CANCER CHEMOTHERAPY ""; ""ABSTRACT ""; ""INTRODUCTION""; ""1) Non-Cellular MDR Mechanisms ""; ""2) Cellular MDR Mechanisms: ""; ""1. Changes in the intracellular accumulation and distribution of the drug ""; ""1a. Alteration of drug influx ""; ""1b. Alteration of drug efflux ""; ""NORMAL TISSUE DISTRIBUTION"" |
""PHYSIOLOGICAL FUNCTIONS OF P-GP """"PHARMACOLOGICAL FUNCTIONS OF P-GP ""; ""P-GP SUBSTRATES ""; ""2. Increase in Drug Detoxification ""; ""3. Alterations of Drug Targets ""; ""4. Increase in DNA Repair Mechanism ""; ""5. Changes in Key Genes Controlling Cell Proliferation ""; ""5a. Changes in genes responsible for cell cycle control ""; ""5b. Abrogation of apoptosis ""; ""6. Micro-Environmental Stress-Mediated Resistance of Solid Tumors ""; ""7. Cancer Cell Dormancy and Resistant Cancer Stem Cells ""; ""MODULATION OF MDR PHENOTYPE "" |
""I. Circumvention of Drug Resistance Induced by P-Gp Pump Protein "" |
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2. |
Record Nr. |
UNINA9910459171503321 |
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Autore |
Baltruschat Doris. |
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Titolo |
Global media ecologies : networked production in film and television / / by Doris Baltruschat |
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Pubbl/distr/stampa |
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New York : , : Routledge, , 2010 |
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ISBN |
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1-136-96618-8 |
1-282-65972-3 |
9786612659720 |
0-203-85098-X |
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Descrizione fisica |
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1 online resource (253 p.) |
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Collana |
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Routledge advances in internationalizing media studies ; ; 6 |
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Disciplina |
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Soggetti |
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Television and globalization |
Television broadcasting - International cooperation |
Television broadcasting - Economic aspects |
Mass media policy |
Mass media and globalization |
Mass media and culture |
Electronic books. |
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Lingua di pubblicazione |
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Formato |
Materiale a stampa |
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Livello bibliografico |
Monografia |
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Note generali |
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Description based upon print version of record. |
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Nota di bibliografia |
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Includes bibliographical references and index. |
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Nota di contenuto |
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Book Cover; Title; Copyright; Contents; Tables, Figures and Maps; Preface and Acknowledgments; Introduction and Overview; 1 International Film and TV Coproduction under Review; 2 Activating Codes and Conventions in Co-produced Docudramas; 3 Media Ecologies in Format Franchising; 4 Formats and Reality TV: The Case of the Idol Franchise; 5 Auditioning for Idol; 6 'Content as Currency': New Alliances between Media and Cultural Agents; 7 Summary and Conclusion; Appendix: International Format Production and Distribution Companies; Glossary; Notes; Bibliography; Index |
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Sommario/riassunto |
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In this study, Baltruschat calls attention to dramatic changes in worldwide media production. Her work provides new insights into industry re-organization, digital media, and audience interactivity as pivotal relationships are redrawn along the entire value chain of |
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production, distribution, and consumption. Based on an international study, she details how cultural agents now negotiate a media landscape through collaborative ventures, co-productions and format franchising. These varied collaborations define the new global media economy and affect a shift across the entire field of cultural |
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